Erschienen in:
01.06.2010 | Brief report
Acceptability of a Non-Woven Device for Vaginal Drug Delivery of Microbicides or Other Active Agents
verfasst von:
Carol L. Joanis, Catherine W. Hart
Erschienen in:
AIDS and Behavior
|
Ausgabe 3/2010
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Abstract
Vaginal microbicides could reduce incidence of HIV. However, the current method of delivering gel formulations (standard applicator) can result in acceptability concerns/issues. This study evaluated the concept of using a non-woven textile material (modified tampon) for vaginal drug delivery. The study was nested within a Phase I randomized safety trial of lime juice concentrations used intra-vaginally. Of 47 women completing the safety trial, 16 were interviewed about their experiences. Overall, women found the concept of non-woven materials for vaginal drug delivery acceptable for use in delivering yeast medications (13 of 16) and STI/HIV preventives (10 of 16).