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22.12.2017 | Original Article

Accuracy of the third molar maturity index in assessing the legal age of 18 years: a systematic review and meta-analysis

verfasst von: Bianca Marques Santiago, Leopoldina Almeida, Yuri Wanderley Cavalcanti, Marcela Baraúna Magno, Lucianne Cople Maia

Erschienen in: International Journal of Legal Medicine | Ausgabe 4/2018

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Abstract

The age estimation is a complex procedure required in the daily practice of legal medicine. The maturity of third molars stands out by the age of 18 because these teeth are still in development. This systematic review aimed to assess the accuracy of the third molar maturity index (I _3M), proposed by Cameriere et al. (2008), in discriminating whether an individual is under or over 18 years. Seven electronic databases were screened: PubMed, Scopus, ISI Web of Science, Cochrane Library, LILACS, SIGLE, and CAPES. Eligible studies included an assessment of I _3M accuracy at the 0.08 cut-off value. The quality assessment was performed by using QUADAS 2. Three meta-analyses (MA) were accomplished: overall, one for males and another for females. From 2397 articles identified, 16 met the eligibility criteria. Of these, two showed high risk of bias, one in the reference standard domain and the other in the flow and timing domain. The percentage of individuals correctly classified ranged from 72.4 to 96.0%. The overall MA showed pooled sensitivity of 0.86 (0.84 to 0.87; p = 0.0000) and pooled specificity of 0.93 (0.92 to 0.94; p = 0.0000). The AUC (area under the summary receiver operator characteristics curve) and DOR (diagnostic odds ratio) values were, respectively, 0.9652 and 104.68, indicating an overall high discrimination effect. Separately, better results of accuracy were found for males. High heterogeneity was achieved for both sensibility (94.6%) and specificity (88.8%). We conclude that the I _3M is a suitable and useful method for estimating adulthood regarding forensic purposes, regardless of gender.

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Titel: Accuracy of the third molar maturity index in assessing the legal age of 18 years: a systematic review and meta-analysis
verfasst von: Bianca Marques Santiago
Leopoldina Almeida
Yuri Wanderley Cavalcanti
Marcela Baraúna Magno
Lucianne Cople Maia
Publikationsdatum: 22.12.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: International Journal of Legal Medicine / Ausgabe 4/2018
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-017-1766-4

Springer Medizin

Accuracy of the third molar maturity index in assessing the legal age of 18 years: a systematic review and meta-analysis

Abstract

Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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