Ausgabe 6/2019
Inhalt (10 Artikel)
Disrupted neuronal trafficking in amyotrophic lateral sclerosis
Katja Burk, R. Jeroen Pasterkamp
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD
Cyril Pottier, Yingxue Ren, Ralph B. Perkerson III, Matt Baker, Gregory D. Jenkins, Marka van Blitterswijk, Mariely DeJesus-Hernandez, Jeroen G. J. van Rooij, Melissa E. Murray, Elizabeth Christopher, Shannon K. McDonnell, Zachary Fogarty, Anthony Batzler, Shulan Tian, Cristina T. Vicente, Billie Matchett, Anna M. Karydas, Ging-Yuek Robin Hsiung, Harro Seelaar, Merel O. Mol, Elizabeth C. Finger, Caroline Graff, Linn Öijerstedt, Manuela Neumann, Peter Heutink, Matthis Synofzik, Carlo Wilke, Johannes Prudlo, Patrizia Rizzu, Javier Simon-Sanchez, Dieter Edbauer, Sigrun Roeber, Janine Diehl-Schmid, Bret M. Evers, Andrew King, M. Marsel Mesulam, Sandra Weintraub, Changiz Geula, Kevin F. Bieniek, Leonard Petrucelli, Geoffrey L. Ahern, Eric M. Reiman, Bryan K. Woodruff, Richard J. Caselli, Edward D. Huey, Martin R. Farlow, Jordan Grafman, Simon Mead, Lea T. Grinberg, Salvatore Spina, Murray Grossman, David J. Irwin, Edward B. Lee, EunRan Suh, Julie Snowden, David Mann, Nilufer Ertekin-Taner, Ryan J. Uitti, Zbigniew K. Wszolek, Keith A. Josephs, Joseph E. Parisi, David S. Knopman, Ronald C. Petersen, John R. Hodges, Olivier Piguet, Ethan G. Geier, Jennifer S. Yokoyama, Robert A. Rissman, Ekaterina Rogaeva, Julia Keith, Lorne Zinman, Maria Carmela Tartaglia, Nigel J. Cairns, Carlos Cruchaga, Bernardino Ghetti, Julia Kofler, Oscar L. Lopez, Thomas G. Beach, Thomas Arzberger, Jochen Herms, Lawrence S. Honig, Jean Paul Vonsattel, Glenda M. Halliday, John B. Kwok, Charles L. White III, Marla Gearing, Jonathan Glass, Sara Rollinson, Stuart Pickering-Brown, Jonathan D. Rohrer, John Q. Trojanowski, Vivianna Van Deerlin, Eileen H. Bigio, Claire Troakes, Safa Al-Sarraj, Yan Asmann, Bruce L. Miller, Neill R. Graff-Radford, Bradley F. Boeve, William W. Seeley, Ian R. A. Mackenzie, John C. van Swieten, Dennis W. Dickson, Joanna M. Biernacka, Rosa Rademakers
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability
Rita Cacace, Bavo Heeman, Sara Van Mossevelde, Arne De Roeck, Julie Hoogmartens, Peter De Rijk, Helena Gossye, Kristof De Vos, Wouter De Coster, Mojca Strazisar, Greet De Baets, Joost Schymkowitz, Frederic Rousseau, Nathalie Geerts, Tim De Pooter, Karin Peeters, Anne Sieben, Jean-Jacques Martin, Sebastiaan Engelborghs, Eric Salmon, Patrick Santens, Rik Vandenberghe, Patrick Cras, Peter P. De Deyn, John C. van Swieten, Cornelia M. van Duijn, Julie van der Zee, Kristel Sleegers, Christine Van Broeckhoven, Johan Goeman, Roeland Crols, Dirk Nuytten, Jan L. De Bleecker, Tim Van Langenhove, Adrian Ivanoiu, Olivier Deryck, Bruno Bergmans, Jan Versijpt, Alex Michotte, Jean Delbeck, Christiana Willems, Nina De Klippel
Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains
Peng Yin, Xiangyu Guo, Weili Yang, Sen Yan, Su Yang, Ting Zhao, Qiang Sun, Yunbo Liu, Shihua Li, Xiao-Jiang Li
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity
Di Hu, Xiaoyan Sun, Xudong Liao, Xinwen Zhang, Sara Zarabi, Aaron Schimmer, Yuning Hong, Christopher Ford, Yu Luo, Xin Qi
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons
Gregor Bieri, Michel Brahic, Luc Bousset, Julien Couthouis, Nicholas J. Kramer, Rosanna Ma, Lisa Nakayama, Marie Monbureau, Erwin Defensor, Birgitt Schüle, Mehrdad Shamloo, Ronald Melki, Aaron D. Gitler
Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms
Maria Masnata, Giacomo Sciacca, Alexander Maxan, Luc Bousset, Hélèna L. Denis, Florian Lauruol, Linda David, Martine Saint-Pierre, Jeffrey H. Kordower, Ronald Melki, Melanie Alpaugh, Francesca Cicchetti
Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles
Andrey Korshunov, Felix Sahm, Konstantin Okonechnikov, Marina Ryzhova, Damian Stichel, Daniel Schrimpf, Belen Casalini, Philipp Sievers, Jochen Meyer, Olga Zheludkova, Andrey Golanov, Peter Lichter, David T. W. Jones, Stefan M. Pfister, Marcel Kool, Andreas von Deimling
Severe bornavirus-encephalitis presenting as Guillain–Barré-syndrome
Roland Coras, Klaus Korn, Stefanie Kuerten, Hagen B. Huttner, Armin Ensser
Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo
André B. Silveira, Lawryn H. Kasper, Yiping Fan, Hongjian Jin, Gang Wu, Timothy I. Shaw, Xiaoyan Zhu, Jon D. Larson, John Easton, Ying Shao, Donald A. Yergeau, Celeste Rosencrance, Kristy Boggs, Michael C. Rusch, Liang Ding, Junyuan Zhang, David Finkelstein, Rachel M. Noyes, Brent L. Russell, Beisi Xu, Alberto Broniscer, Cynthia Wetmore, Stanley B. Pounds, David W. Ellison, Jinghui Zhang, Suzanne J. Baker