Introduction
Definition and prevalence of acute advanced AS
Pathophysiology
Treatment
Medical therapy
Percutaneous BAV
First author, year | n | Male, % | Age (years) | STS score (%) | Mean gradient pre-BAV (mmHg) | Mean gradient post- BAV (mmHg) | Follow-up | Death, % | Stroke, % | Major vascular complications, % |
---|---|---|---|---|---|---|---|---|---|---|
Ben-Dor, 2010 [62] | 262 | 44.7 | 81.7 ± 9.8 | 13.3 ± 6.7 | 42.0 ± 13.9 | 31.9 ± 11.8 | 181 days | 50 | 1.9 | 6.9 |
Saia, 2013 [30] | 415 | 44.3 | 77.5 ± 10.9 | - | 48.7 ± 18.1 | 31.7 ± 12.8 | 2-year | 57.4 | 5.6 | 3.4 |
Eltchaninoff, 2014 [38] | 323 | 58.2 | 80.5 ± 9.9 | - | 44.4 ± 18.9 | 20.7 ± 11.0 | 5-year | 78a | 1.8 | 6.8 |
Szerlip, 2017 [37] | 100 | - | 80.6 ± 9.6 | 11.4 ± 7.1 | 26.1 | - | 1-year | 41 | 1.3 | 3.9 |
Alkhouli, 2017 [63] | 3168 | 51.1 | 82 ± 7.8 | - | - | - | In-hospital | 8.5 | 1.8 | 7.6 |
Bongiovanni, 2018 [14] | 118 | 55.9 | 81.3 ± 7.6 | - | - | - | 30-day | 33 | 0 | 3.4 |
Eugène, 2018 [36] | 40 | 55 | 79 ± 9 | 26 ± 15 | 47 ± 15 | 32 ± 10 | 2-year | 68 | - | 0 |
Debry, 2018 [20] | 44 | 75 | 77.3 ± 8.1 | 23.4 ± 11.6 | 39.0 ± 14.0 | 25.3 ± 11.0 | 1-year | 70 | 0 | 0 |
Bularga, 2020 [35] | 167 | 52.1 | 80.0 | - | 42.0 | 32.0 | 1-year | 43 | 1.2 | 0.6 |
TAVR
First author, year | n | Male, n (%) | Age (years) | STS score (%) | NYHA class IV, n (%) | Cardiogenic shock, n (%) | Femoral access, n (%) | Self-expandable valve, n (%) | Balloon-expandable valve, n (%) | TAVR in degenerated prosthesis, n (%) | MCS, n (%) |
---|---|---|---|---|---|---|---|---|---|---|---|
Landes, 2016 [16] | 27 | 12 (44.5) | 80.1 ± 9.7 | 9.7 | 17 (63) | 0 | 26 (96.3) | 22(81.5) | 5(18.5) | 0 | 0 |
Frerker, 2016 [15] | 27 | 12 (44.5) | 78 ± 9 | 27 (100) | 25 (92.5) | 16 (59.3) | 11 (40.7) | 0 | 0 | ||
Kolte, 2018 [12] | 3952 | 2050 (51.8) | 84 | 11.8 | 2087 (52.8) | 97 (2.5) | 2980 (75.4) | 931 (23.6) | 2984 (75.5) | 202 (5.1) | 47 (1.2) |
Abdelaziz, 2018 [8] | 76 | 38 (50) | 81.7 ± 6.8 | 76 (100) | 0 | 64 (84.2) | 32(42) | 0 | 0 | 0 | |
Bongiovanni, 2018 [14] | 23 | 19 (82.6) | 76.0 ± 11.4 | 22 (95.7) | 2 (8.7) | - | 8 (34.8) | 15 (65.2) | 0 | 0 | |
Elbadawi, 2020 [11] | 10,089 | 5017 (49.7) | 81.0 ± 9.05 | 8196 (81.2) | 348 (3.4) | ||||||
Patel, 2020 [41] | 170 | 88 (51.8) | 83.1 ± 7.6 | 164 (96.5) | 16 (9.4) | 143 (84.1) | 0 | 0 | |||
Huang, 2019 [64] | 31 | 23 (74.2) | 73.1 ± 13.9 | 26 (83.9) | 5 (16.1) | 25 (80.6) | 16 (51.6) | ||||
Fraccaro, 2020 [13] | 51 | 25 (49) | 75.8 ± 12.9 | 19.2 | 51 (100) | 45 (88.2) | 30(58.8) | 12 (23.5) | 13 (25.5) | 6 (11.7) | |
Jalava, 2020 [65] | 210 | 99 (47.1) | 80.7 ± 6.6 | 8.1 | 210 (100) | ||||||
Enta, 2020 [39] | 87 | 26 (29.8) | 84.9 ± 7.0 | 13.7 | 77 (88.5) | 72 (82.8) | 5(5.8) | 82 (94.2) | 14 (16.1) | ||
Maidman, 2020 [42] | 17 | 2 (11.7) | 74.7 ± 8.9 | 22.3 | 15 (88.2) | 9 (52.9) | 17 (100) | 1 (5.9) | 16 (94.1) | 2 (11.7) | |
Bianco, 2021 [40] | 247 | 131 (53) | 82 | 148 (59.9) | 3 (1.2) | 203 (82.2) | 144 (58.3) | 103 (41.7) | 29 (11.7) | ||
Lux, 2021 [66] | 53 | 30 (56.6) | 79 | 36 (67.9) | 7 (13.2) | ||||||
Kaewkes, 2021 [67] | 139 | 74 (53) | 82.2 ± 9.6 | 6.7 | 132 (95%) | 129 (93) | 23 (16) | 116 (84) |
First author, year | n | Device success, n (%) | Follow-up | Stroke, n (%) | Major bleeding, n (%) | Vascular complications, n (%) | Acute kidney injury, n (%) | Moderate/severe PVL, n (%) | Mortality at longest follow-up, n (%) |
---|---|---|---|---|---|---|---|---|---|
Landes, 2016 [16] | 27 | 23 (85.2) | 30-day | 1 (3.7) | 1 (3.7) | 5 (18.5) | 4 (14.8) | 2 (9.5) | 1 (3.7) |
Frerker, 2016 [15] | 27 | 24 (88.9) | 1-year | 1 (3.7) | 1 (3.7) | 9 (33.3) | 8 (29.6) | 1 (3.7) | 11 (40.7) |
Kolte, 2018 [12] | 3952 | 3659 (92.6) | 1-year | 91 (2.3) | 324 (8.3) | 39 (1.0) | 323 (8.2) | 159 (4.0) | 1185 (29) |
Abdelaziz, 2018 [8] | 76 | 2-year | 2 (2.6) | 7 (9.2) | 4 (5.3) | 14 (18.4) | |||
Bongiovanni, 2018 [14] | 23 | 30-day | 2 (8.7) | 1 (4.3) | 5 (21.7) | 3 (13) | 1 (4.3) | 5 (23.8) | |
Elbadawi, 2020 [11] | 10,089 | In-hospital | 274 (2.7) | 3628 (36) | 214 (2.1) | 2827 (28) | 565 (5.6) | ||
Patel, 2020 [41] | 170 | 30-day | 2 (1.2) | 9 (5.3) | 20 (11.8) | 9 (5.3) | |||
Huang, 2019 [64] | 31 | 2-year | 3 (10) | 2 (6.7) | 5 (16.7) | 5 (16.7) | 0 | 13 (41.9) | |
Fraccaro, 2020 [13] | 51 | 30-day | 1 (2) | 2 (3.9) | 2 (3.9) | 17 (33.4) | 8 (15.6) | 6 (11.8) | |
Jalava, 2019 [65] | 210 | 30-day | 8 (3.8) | 56 (26.8) | 26 (12.3) | 7 (3.3) | 10 (4.8) | ||
Enta, 2020 [39] | 87 | 76 (87.4) | 30-day | 3 (3.4) | 19 (21.8) | 13 (14.9) | 20 (22.9) | 2 (2.4) | 8 (9.2) |
Maidman, 2020 [42] | 17 | 30-day | 0 | 0 | 2 (11.7) | ||||
Bianco, 2021 [40] | 247 | 30-day | 9 (3.6) | 7 (2.8) | 13 (5.2) | 16 (6.5) | |||
Lux, 2021 [66] | 53 | 1-year | 1 (1.9) | 1 (1.9) | 15 (28.3) | ||||
Kaewkes, 2021 [67] | 139 | 30-day | 5 (4) | 9 (6) | 8 (5.7) | 5 (4) | 46 (39) | 11 (8) |