Erschienen in:
01.04.2010 | CASE REPORT
Acute Hepatitis Due to Epstein–Barr Virus in an Immunocompetent Patient
verfasst von:
Neha Pagidipati, Keith L. Obstein, Rachel Rucker-Schmidt, Robert D. Odze, Christopher C. Thompson
Erschienen in:
Digestive Diseases and Sciences
|
Ausgabe 4/2010
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Excerpt
Epstein–Barr virus (EBV) infects over 90% of humans and persists throughout life. Typically, EBV infection in infants and children is asymptomatic or is manifest by nonspecific symptoms [
1]. In adolescents and adults, EBV infection can result in infectious mononucleosis, which presents with the triad of fever, lymphadenopathy, and pharyngitis in over 50% of cases. Though often unrecognized, EBV infection can cause mild elevation in serum aminotransferase levels in 90% of patients, with clinically significant EBV-induced liver damage occurring only rarely in immunocompetent individuals [
2,
3]. We present a 21-year-old female diagnosed with acute clinically significant EBV-induced hepatitis that was confirmed by pathology and serologic studies. We also review the literature on the clinical presentation, diagnostic criteria, histopathological characteristics, and management of EBV hepatitis. …
