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Erschienen in: DNP - Der Neurologe & Psychiater 7-8/2013

07.08.2013 | Fortbildung

Aktuelle Studienlage zur Sekundärprävention

Schlaganfall

verfasst von: PD Dr. med. Christian H. Nolte, Prof. Dr. med. Matthias Endres

Erschienen in: DNP – Die Neurologie & Psychiatrie | Ausgabe 7-8/2013

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Zusammenfassung

Der Schlaganfall ist weltweit die zweithäufigste Todesursache und die führende Ursache für erworbene Behinderungen. Nach einem Schlaganfall ist das Risiko für einen weiteren Schlaganfall hoch. Eine effektive Sekundärprävention kann einen weiteren Schlaganfall und andere vaskuläre Ereignisse wie Herzinfarkte oder vaskulären Tod verhindern.

Literatur
  1. Mohan KM, Wolfe CDA, Rudd AG, Heuschmann PU, Kolominsky-Rabas PL, Grieve AP. Risk and cumulative risk of stroke recurrence: a systematic review and meta-analysis. Stroke 2011; 42(5):1489–1494.PubMedView Article
  2. Davis SM, Donnan GA. Clinical practice. Secondary prevention after ischemic stroke or transient ischemic attack. N. Engl. J. Med. 2012; 366(20):1914–1922.PubMedView Article
  3. Leistner S, Benik S, Laumeier I, Ziegler A, Nieweler G, Nolte CH et al. Secondary prevention after minor stroke and TIA - usual care and development of a support program. PLoS ONE 2012; 7(12):e49985.View Article
  4. Nolte CH, Müller-Nordhorn J, Jungehülsing GJ, Rossnagel K, Reich A, Klein M et al. [Symptoms, risk factors, and etiology of transient ischemic attack and stroke]. Nervenarzt 2005; 76(10):1231–1232, 1234-6, 1238.PubMedView Article
  5. Goldstein LB, Adams R, Becker K, Furberg CD, Gorelick PB, Hademenos G et al. Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. Circulation 2001; 103(1):163–182.PubMedView Article
  6. Rothwell PM, Algra A, Amarenco P. Medical treatment in acute and long-term secondary prevention after transient ischaemic attack and ischaemic stroke. Lancet 2011; 377(9778):1681–1692.PubMedView Article
  7. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001; 358(9287):1033–1041.
  8. Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N. Engl. J. Med. 2000; 342(3):145–153.PubMedView Article
  9. Yusuf S, Diener H, Sacco RL, Cotton D, Ounpuu S, Lawton WA et al. Telmisartan to prevent recurrent stroke and cardiovascular events. N. Engl. J. Med. 2008; 359(12):1225–1237.PubMedView Article
  10. Collins R, Armitage J, Parish S, Sleight P, Peto R. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363(9411):757–767.PubMedView Article
  11. Amarenco P, Goldstein LB, Szarek M, Sillesen H, Rudolph AE, Callahan A et al. Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke 2007; 38(12):3198–3204.PubMedView Article
  12. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324(7329):71–86.
  13. Diener H, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M et al. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet; 364(sn9431):pp331-337.
  14. Bhatt DL, Fox KAA, Hacke W, Berger PB, Black HR, Boden WE et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N. Engl. J. Med. 2006; 354(16):1706–1717.PubMedView Article
  15. Benavente OR, Hart RG, McClure LA, Szychowski JM, Coffey CS, Pearce LA. Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. N. Engl. J. Med. 2012; 367(9):817–825.PubMedView Article
  16. Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A et al. Dabigatran versus warfarin in patients with atrial fibrillation. N. Engl. J. Med. 2009; 361(12):1139–1151.PubMedView Article
  17. Patel MR, Mahaffey KW, Garg J, Pan G, Singer DE, Hacke W et al.Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N. Engl. J. Med. 2011; 365(10):883–8891.PubMedView Article
  18. Connolly SJ, Eikelboom J, Joyner C, Diener H, Hart R, Golitsyn S et al. Apixaban in patients with atrial fibrillation. N. Engl. J. Med. 2011; 364(9):806–817.PubMedView Article
  19. Granger CB, Alexander JH, McMurray JJV, Lopes RD, Hylek EM, Hanna M et al. Apixaban versus warfarin in patients with atrial fibrillation. N. Engl. J. Med. 2011; 365(11):981–992.PubMedView Article
  20. Towfighi A, Markovic D, Ovbiagele B. Impact of a healthy lifestyle on all-cause and cardiovascular mortality after stroke in the USA. J. Neurol. Neurosurg. Psychiatr. 2012; 83(2):146–151.PubMedView Article
  21. Dehghan M, Mente A, Teo KK, Gao P, Sleight P, Dagenais G et al. Relationship between healthy diet and risk of cardiovascular disease among patients on drug therapies for secondary prevention: a prospective cohort study of 31 546 high-risk individuals from 40 countries. Circulation 2012; 126(23):2705–2712.PubMedView Article
  22. Nolte CH, Jungehulsing GJ, Rossnagel K, Roll S, Haeusler KG, Reich A et al. Vascular risk factor awareness before and pharmacological treatment before and after stroke and TIA. Eur. J. Neurol. 2009; 16(6):678–683.PubMedView Article
  23. Stroebele N, Müller-Riemenschneider F, Nolte CH, Müller-Nordhorn J, Bockelbrink A, Willich SN. Knowledge of risk factors, and warning signs of stroke: a systematic review from a gender perspective. Int J Stroke 2011; 6(1):60–66.PubMedView Article
  24. Meier B, Kalesan B, Mattle HP, Khattab AA, Hildick-Smith D, Dudek D et al. Percutaneous closure of patent foramen ovale in cryptogenic embolism. N. Engl. J. Med. 2013; 368(12):1083–1091.PubMedView Article
  25. Carroll JD, Saver JL, Thaler DE, Smalling RW, Berry S, MacDonald LA et al. Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N. Engl. J. Med. 2013; 368(12):1092–1100.PubMedView Article
  26. Furlan AJ, Reisman M, Massaro J, Mauri L, Adams H, Albers GW et al. Closure or medical therapy for cryptogenic stroke with patent foramen ovale. N. Engl. J. Med. 2012; 366(11):991–999.PubMedView Article
  27. Chimowitz MI, Lynn MJ, Derdeyn CP, Turan TN, Fiorella D, Lane BF et al. Stenting versus aggressive medical therapy for intracranial arterial stenosis. N. Engl. J. Med. 2011; 365(11):993–1003.PubMedView Article
Metadaten
Titel
Aktuelle Studienlage zur Sekundärprävention
Schlaganfall
verfasst von
PD Dr. med. Christian H. Nolte
Prof. Dr. med. Matthias Endres
Publikationsdatum
07.08.2013
Verlag
Urban & Vogel
Erschienen in
DNP – Die Neurologie & Psychiatrie / Ausgabe 7-8/2013
Print ISSN: 2731-8168
Elektronische ISSN: 2731-8176
DOI
https://doi.org/10.1007/s15202-013-0355-8

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