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Erschienen in: Acta Diabetologica 12/2019

06.09.2019 | Original Article

Alcohol consumption or cigarette smoking and cardiovascular disease risk in youth with type 1 diabetes

verfasst von: Giuliana Valerio, Enza Mozzillo, Eugenio Zito, Elena De Nitto, Giulio Maltoni, Marco Marigliano, Stefano Zucchini, Claudio Maffeis, Adriana Franzese

Erschienen in: Acta Diabetologica | Ausgabe 12/2019

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Abstract

Aim

To assess the association between alcohol consumption and/or cigarette smoking with other unhealthy behaviors and clinical cardiovascular risk factors in youth with type 1 diabetes.

Methods

Two hundred and twenty-eight youth with type 1 diabetes (age 13–19 years) were consecutively enrolled in three Regional Pediatric Diabetes Centers in Italy. Demographic, anthropometric, lifestyle (adherence to the Mediterranean diet pattern and sports participation) and laboratory parameters were compared among youth reporting isolated or combined alcohol consumption and/or cigarette smoking.

Results

Ten percent of the youth reported alcohol consumption, 10% cigarette smoking and 6% both alcohol and cigarette use; 74% did not report alcohol or cigarette use. Compared to non-drinker non-smoker youth, smokers showed significantly higher percentages of each of the behavioral and clinical cardiovascular risk factors. Drinkers showed a significantly higher proportion of abdominal adiposity, dyslipidemia and poor adherence to the Mediterranean diet. Alcohol consumption was independently associated with both dyslipidemia and high glycosylated hemoglobin.

Conclusions

Our findings emphasize the need to increase the awareness of youth with T1D about the negative impact of alcohol drinking on cardiovascular risk, since the effects of alcohol might be underestimated with respect to the well-known detrimental effects of smoking. Clustering of unhealthy lifestyle should be discouraged in type 1 diabetes youth in order to promote cardiovascular protection.
Literatur
1.
Zurück zum Zitat Huxley RR, Peters SA, Mishra GD, Woodward M (2015) Risk of all-cause mortality and vascular events in women versus men with type 1 diabetes: a systematic review and meta-analysis. Lancet Diabetes Endocrinol 3(3):198–206CrossRefPubMed Huxley RR, Peters SA, Mishra GD, Woodward M (2015) Risk of all-cause mortality and vascular events in women versus men with type 1 diabetes: a systematic review and meta-analysis. Lancet Diabetes Endocrinol 3(3):198–206CrossRefPubMed
2.
Zurück zum Zitat Rawshani A, Sattar N, Franzén S et al (2018) Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study. Lancet 392(10146):477–486CrossRefPubMedPubMedCentral Rawshani A, Sattar N, Franzén S et al (2018) Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study. Lancet 392(10146):477–486CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Cho YH, Craig ME, Donaghue KC (2014) Puberty as an accelerator for diabetes complications. Pediatr Diabetes 15(1):18–26CrossRefPubMed Cho YH, Craig ME, Donaghue KC (2014) Puberty as an accelerator for diabetes complications. Pediatr Diabetes 15(1):18–26CrossRefPubMed
5.
Zurück zum Zitat Sawyer SM, Drew S, Yeo MS, Britto MT (2007) Adolescents with a chronic condition: challenges living, challenges treating. Lancet 369(9571):1481–1489CrossRefPubMed Sawyer SM, Drew S, Yeo MS, Britto MT (2007) Adolescents with a chronic condition: challenges living, challenges treating. Lancet 369(9571):1481–1489CrossRefPubMed
6.
Zurück zum Zitat Katz M, Giani E, Laffel L (2015) Challenges and opportunities in the management of cardiovascular risk factors in youth with type 1 diabetes: lifestyle and beyond. Curr Diabetes Rep 15(12):119CrossRef Katz M, Giani E, Laffel L (2015) Challenges and opportunities in the management of cardiovascular risk factors in youth with type 1 diabetes: lifestyle and beyond. Curr Diabetes Rep 15(12):119CrossRef
7.
Zurück zum Zitat Gonder-Frederick L (2014) Lifestyle modifications in the management of type 1 diabetes: still relevant after all these years? Diabetes Technol Ther 16(11):695–698CrossRefPubMedPubMedCentral Gonder-Frederick L (2014) Lifestyle modifications in the management of type 1 diabetes: still relevant after all these years? Diabetes Technol Ther 16(11):695–698CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Rovner AJ, Nansel TR (2009) Are children with type 1 diabetes consuming a healthful diet?: a review of the current evidence and strategies for dietary change. Diabetes Educ 35(1):97–107CrossRefPubMed Rovner AJ, Nansel TR (2009) Are children with type 1 diabetes consuming a healthful diet?: a review of the current evidence and strategies for dietary change. Diabetes Educ 35(1):97–107CrossRefPubMed
9.
Zurück zum Zitat Patino-Alonso MC, Recio-Rodríguez JI, Magdalena-Belio JF et al (2015) Clustering of lifestyle characteristics and their association with cardio-metabolic health: the Lifestyles and Endothelial Dysfunction (EVIDENT) study. Br J Nutr 114(6):943–951CrossRefPubMed Patino-Alonso MC, Recio-Rodríguez JI, Magdalena-Belio JF et al (2015) Clustering of lifestyle characteristics and their association with cardio-metabolic health: the Lifestyles and Endothelial Dysfunction (EVIDENT) study. Br J Nutr 114(6):943–951CrossRefPubMed
10.
Zurück zum Zitat Elmesmari R, Martin A, Reilly JJ, Paton JY (2018) Comparison of accelerometer measured levels of physical activity and sedentary time between obese and non-obese children and adolescents: a systematic review. BMC Pediatr 18(1):106CrossRefPubMedPubMedCentral Elmesmari R, Martin A, Reilly JJ, Paton JY (2018) Comparison of accelerometer measured levels of physical activity and sedentary time between obese and non-obese children and adolescents: a systematic review. BMC Pediatr 18(1):106CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Mozzillo E, Zito E, Maffeis C et al (2017) Unhealthy lifestyle habits and diabetes-specific health-related quality of life in youths with type 1 diabetes. Acta Diabetol 54(12):1073–1080CrossRefPubMed Mozzillo E, Zito E, Maffeis C et al (2017) Unhealthy lifestyle habits and diabetes-specific health-related quality of life in youths with type 1 diabetes. Acta Diabetol 54(12):1073–1080CrossRefPubMed
12.
Zurück zum Zitat Maffeis C, Grezzani A, Pietrobelli A, Provera S, Tatò L (2001) Does waist circumference predict fat gain in children? Int J Obes 25(7):978–983CrossRef Maffeis C, Grezzani A, Pietrobelli A, Provera S, Tatò L (2001) Does waist circumference predict fat gain in children? Int J Obes 25(7):978–983CrossRef
13.
Zurück zum Zitat Cacciari E, Milani S, Balsamo A et al (2006) Italian cross-sectional growth charts for height, weight and BMI (2 to 20 year). J Endocrinol Invest 29:581–593CrossRefPubMed Cacciari E, Milani S, Balsamo A et al (2006) Italian cross-sectional growth charts for height, weight and BMI (2 to 20 year). J Endocrinol Invest 29:581–593CrossRefPubMed
14.
Zurück zum Zitat Valerio G, Balsamo A, Baroni MG et al (2017) Childhood obesity classification systems and cardiometabolic risk factors: a comparison of the Italian, World Health Organization and International Obesity Task Force references. Ital J Pediatr 43(1):19CrossRefPubMedPubMedCentral Valerio G, Balsamo A, Baroni MG et al (2017) Childhood obesity classification systems and cardiometabolic risk factors: a comparison of the Italian, World Health Organization and International Obesity Task Force references. Ital J Pediatr 43(1):19CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Maffeis C, Banzato C, Talamini G, Obesity Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (2008) Waist-to-height ratio, a useful index to identify high metabolic risk in overweight children. J Pediatr 152(2):207–213CrossRefPubMed Maffeis C, Banzato C, Talamini G, Obesity Study Group of the Italian Society of Pediatric Endocrinology and Diabetology (2008) Waist-to-height ratio, a useful index to identify high metabolic risk in overweight children. J Pediatr 152(2):207–213CrossRefPubMed
16.
Zurück zum Zitat Serra-Majem L, Ribas L, Ngo J et al (2004) Food, youth and the Mediterranean diet in Spain. Development of KIDMED, Mediterranean diet quality index in children and adolescents. Public Health Nutr 7:931–935CrossRefPubMed Serra-Majem L, Ribas L, Ngo J et al (2004) Food, youth and the Mediterranean diet in Spain. Development of KIDMED, Mediterranean diet quality index in children and adolescents. Public Health Nutr 7:931–935CrossRefPubMed
17.
Zurück zum Zitat Di Bonito P, Moio N, Scilla C et al (2012) Usefulness of the high triglyceride-to-HDL cholesterol ratio to identify cardiometabolic risk factors and preclinical signs of organ damage in outpatient children. Diabetes Care 35:158e62CrossRef Di Bonito P, Moio N, Scilla C et al (2012) Usefulness of the high triglyceride-to-HDL cholesterol ratio to identify cardiometabolic risk factors and preclinical signs of organ damage in outpatient children. Diabetes Care 35:158e62CrossRef
18.
Zurück zum Zitat Weitzman ER, Ziemnik RE, Huang Q, Levy S (2015) Alcohol and marijuana use and treatment nonadherence among medically vulnerable youth. Pediatrics 136(3):450–457CrossRefPubMedPubMedCentral Weitzman ER, Ziemnik RE, Huang Q, Levy S (2015) Alcohol and marijuana use and treatment nonadherence among medically vulnerable youth. Pediatrics 136(3):450–457CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Barnard KD, Dyson P, Sinclair JM et al (2014) Alcohol health literacy in young adults with type 1 diabetes and its impact on diabetes management. Diabet Med 31(12):1625–1630CrossRefPubMed Barnard KD, Dyson P, Sinclair JM et al (2014) Alcohol health literacy in young adults with type 1 diabetes and its impact on diabetes management. Diabet Med 31(12):1625–1630CrossRefPubMed
20.
Zurück zum Zitat Martínez-Aguayo A, Araneda JC, Fernandez D, Gleisner A, Perez V, Codner E (2007) Tobacco, alcohol, and illicit drug use in adolescents with diabetes mellitus. Pediatr Diabetes 8(5):265–271CrossRefPubMed Martínez-Aguayo A, Araneda JC, Fernandez D, Gleisner A, Perez V, Codner E (2007) Tobacco, alcohol, and illicit drug use in adolescents with diabetes mellitus. Pediatr Diabetes 8(5):265–271CrossRefPubMed
21.
Zurück zum Zitat Hermann JM, Meusers M, Bachran R et al (2017) Self-reported regular alcohol consumption in adolescents and emerging adults with type 1 diabetes: a neglected risk factor for diabetic ketoacidosis? Multicenter analysis of 29 630 patients from the DPV registry. Pediatr Diabetes 18(8):817–823CrossRefPubMed Hermann JM, Meusers M, Bachran R et al (2017) Self-reported regular alcohol consumption in adolescents and emerging adults with type 1 diabetes: a neglected risk factor for diabetic ketoacidosis? Multicenter analysis of 29 630 patients from the DPV registry. Pediatr Diabetes 18(8):817–823CrossRefPubMed
22.
Zurück zum Zitat Klop B, do Rego AT, Cabezas MC (2013) Alcohol and plasma triglycerides. Curr Opin Lipidol 24(4):321–326CrossRefPubMed Klop B, do Rego AT, Cabezas MC (2013) Alcohol and plasma triglycerides. Curr Opin Lipidol 24(4):321–326CrossRefPubMed
23.
24.
Zurück zum Zitat Ahmed AT, Karter AJ, Liu J (2006) Alcohol consumption is inversely associated with adherence to diabetes self-care behaviours. Diabet Med 23(7):795–802CrossRefPubMedPubMedCentral Ahmed AT, Karter AJ, Liu J (2006) Alcohol consumption is inversely associated with adherence to diabetes self-care behaviours. Diabet Med 23(7):795–802CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Brinton EA (2012) Effects of ethanol intake on lipoproteins. Curr Atheroscler Rep 14(2):108–114CrossRefPubMed Brinton EA (2012) Effects of ethanol intake on lipoproteins. Curr Atheroscler Rep 14(2):108–114CrossRefPubMed
26.
Zurück zum Zitat American Diabetes Association 5 (2019) Lifestyle management: standards of medical care in diabetes-2019. Diabetes Care 42(Suppl 1):S46–S60CrossRef American Diabetes Association 5 (2019) Lifestyle management: standards of medical care in diabetes-2019. Diabetes Care 42(Suppl 1):S46–S60CrossRef
27.
Zurück zum Zitat Cameron FJ, Garvey K, Hood KK, Acerini CL, Codner E (2018) ISPAD clinical practice consensus guidelines 2018: diabetes in adolescence. Pediatr Diabetes 19(Suppl 27):250–261CrossRefPubMed Cameron FJ, Garvey K, Hood KK, Acerini CL, Codner E (2018) ISPAD clinical practice consensus guidelines 2018: diabetes in adolescence. Pediatr Diabetes 19(Suppl 27):250–261CrossRefPubMed
28.
Zurück zum Zitat Śliwińska-Mossoń M, Milnerowicz H (2017) The impact of smoking on the development of diabetes and its complications. Diab Vasc Dis Res 14(4):265–276CrossRefPubMed Śliwińska-Mossoń M, Milnerowicz H (2017) The impact of smoking on the development of diabetes and its complications. Diab Vasc Dis Res 14(4):265–276CrossRefPubMed
29.
Zurück zum Zitat Cavallo F, Lemma P, Dalmasso P, Vieno A, Lazzeri G, Galeone D (2016) Italian data report from the international study HBSC 2014 (ISBN 9788875901028) Cavallo F, Lemma P, Dalmasso P, Vieno A, Lazzeri G, Galeone D (2016) Italian data report from the international study HBSC 2014 (ISBN 9788875901028)
30.
Zurück zum Zitat Reynolds K, Liese AD, Anderson AM et al (2011) Prevalence of tobacco use and association between CVD risk factors and cigarette smoking in youth with type 1 or type 2 diabetes mellitus. J Pediatr 158(4):594–601.e1CrossRefPubMed Reynolds K, Liese AD, Anderson AM et al (2011) Prevalence of tobacco use and association between CVD risk factors and cigarette smoking in youth with type 1 or type 2 diabetes mellitus. J Pediatr 158(4):594–601.e1CrossRefPubMed
31.
Zurück zum Zitat Kar D, Gillies C, Zaccardi F et al (2016) Relationship of CVD parameters in non-smokers, current smokers, and quitters in diabetes: a systematic review and meta-analysis. Cardiovasc Diabetol 15(1):158CrossRefPubMedPubMedCentral Kar D, Gillies C, Zaccardi F et al (2016) Relationship of CVD parameters in non-smokers, current smokers, and quitters in diabetes: a systematic review and meta-analysis. Cardiovasc Diabetol 15(1):158CrossRefPubMedPubMedCentral
32.
Zurück zum Zitat Lisha NE, Sussman S (2010) Relationship of high school and college sports participation with alcohol, tobacco, and illicit drug use: a review. Addict Behav 35(5):399–407CrossRefPubMedPubMedCentral Lisha NE, Sussman S (2010) Relationship of high school and college sports participation with alcohol, tobacco, and illicit drug use: a review. Addict Behav 35(5):399–407CrossRefPubMedPubMedCentral
33.
Zurück zum Zitat Kwan M, Bobko S, Faulkner G, Donnelly P, Cairney J (2014) Sport participation and alcohol and illicit drug use in adolescents and young adults: a systematic review of longitudinal studies. Addict Behav 39(3):497–506CrossRefPubMed Kwan M, Bobko S, Faulkner G, Donnelly P, Cairney J (2014) Sport participation and alcohol and illicit drug use in adolescents and young adults: a systematic review of longitudinal studies. Addict Behav 39(3):497–506CrossRefPubMed
34.
Zurück zum Zitat Tielemans SM, Soedamah-Muthu SS, De Neve M et al (2013) Association of physical activity with all-cause mortality and incident and prevalent cardiovascular disease among patients with type 1 diabetes: the EURODIAB Prospective Complications Study. Diabetologia 56(1):82–91CrossRefPubMed Tielemans SM, Soedamah-Muthu SS, De Neve M et al (2013) Association of physical activity with all-cause mortality and incident and prevalent cardiovascular disease among patients with type 1 diabetes: the EURODIAB Prospective Complications Study. Diabetologia 56(1):82–91CrossRefPubMed
Metadaten
Titel
Alcohol consumption or cigarette smoking and cardiovascular disease risk in youth with type 1 diabetes
verfasst von
Giuliana Valerio
Enza Mozzillo
Eugenio Zito
Elena De Nitto
Giulio Maltoni
Marco Marigliano
Stefano Zucchini
Claudio Maffeis
Adriana Franzese
Publikationsdatum
06.09.2019
Verlag
Springer Milan
Erschienen in
Acta Diabetologica / Ausgabe 12/2019
Print ISSN: 0940-5429
Elektronische ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-019-01415-5

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