Alpha-methyltryptamine and 5-(2-methylaminopropyl)-benzofuran (5-MAPB) fatal co-intoxication: case report and review of literature
- 23.04.2024
- Case Report
Erschienen in:
- Verfasst von
- Marie Epain
- Nathalie Cartiser
- Fabien Bevalot
- Charline Bottinelli
- Camille Chatenay
- Laurent Fanton
- Erschienen in
- International Journal of Legal Medicine | Ausgabe 5/2024
Abstract
The scientific literature contains little reliable data regarding new psychoactive substances and designer drugs, making it difficult to assess toxic blood levels and potentially lethal threshold. Here, we report a fatal co-intoxication involving two uncommon drugs ‒ alpha-methyltryptamine (AMT) and 5-(2-methylaminopropyl)-benzofuran (5-MAPB) ‒ combined with exposure to benzodiazepines, ephedrine, and norephedrine. AMT and 5-MAPB were quantified using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC/MS-MS), revealing concentrations of AMT 4690 ng/mL and 5-MAPB 101 ng/mL in postmortem peripheral blood. We additionally reviewed the literature to help interpret the likely roles of these molecules in the occurrence of death.
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- Titel
- Alpha-methyltryptamine and 5-(2-methylaminopropyl)-benzofuran (5-MAPB) fatal co-intoxication: case report and review of literature
- Verfasst von
-
Marie Epain
Nathalie Cartiser
Fabien Bevalot
Charline Bottinelli
Camille Chatenay
Laurent Fanton
- Publikationsdatum
- 23.04.2024
- Verlag
- Springer Berlin Heidelberg
- Erschienen in
-
International Journal of Legal Medicine / Ausgabe 5/2024
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596 - DOI
- https://doi.org/10.1007/s00414-024-03236-w
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