Skip to main content
main-content

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Molecular Autism 1/2014

An examination of autism spectrum traits in adolescents with anorexia nervosa and their parents

Zeitschrift:
Molecular Autism > Ausgabe 1/2014
Autoren:
Charlotte Rhind, Elena Bonfioli, Rebecca Hibbs, Elizabeth Goddard, Pamela Macdonald, Simon Gowers, Ulrike Schmidt, Kate Tchanturia, Nadia Micali, Janet Treasure
Wichtige Hinweise
Nadia Micali and Janet Treasure contributed equally to this work.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

CR was a project coordinator for the Experienced Carers Helping Others (ECHO) study and carried out data collection, statistical analysis and drafted the manuscript. EB prepared data for analysis. RH was a project coordinator for ECHO, involved in the setup of the ECHO study, carried out data collection and critical appraisal of the manuscript content. EG, PM, SG, and US were involved in the design and setup of the study and contributed to the interpretation of data and critical appraisal of the manuscript content. SG was also Principal Investigator at one of the study recruitment sites. KT contributed to the interpretation of data and critical appraisal of the manuscript content. NM conducted the Development and Well-being Assessment clinician ratings, supervised statistical analysis, contributed to interpretation of data and was involved in revising the manuscript critically for important intellectual content. JT conceived of the study, participated in its design and coordination, contributed to the interpretation of results, and was involved in drafting of the manuscript and revising it critically for important intellectual content. All authors read and approved the final manuscript.

Abstract

Background

There may be a link between anorexia nervosa and autism spectrum disorders. The aims of this study were to examine whether adolescents with anorexia nervosa have autism spectrum and/or obsessive-compulsive traits, how many would meet diagnostic criteria for autism spectrum disorder, and whether these traits are shared by parents.

Methods

A total of 150 adolescents receiving outpatient treatment for anorexia nervosa or subthreshold anorexia nervosa and their parents completed the autism spectrum disorder and eating disorder sections of the Development and Well-being Assessment. Patients also completed the Children Yale-Brown Obsessive-Compulsive Scale and other measures of psychiatric morbidity, and parents completed the short Autism Quotient and Obsessive-Compulsive Inventory Revised.

Results

Adolescents with anorexia nervosa had a below average social aptitude (19% below cut-off) and high levels of peer relationship problems (39% above cut-off) and obsessive-compulsive symptoms (56% above cut-off). Six cases (4%, all females) were assigned a possible (n = 5) or definite (n = 1) diagnosis of autism spectrum disorder. Parental levels of autism spectrum and obsessive-compulsive traits were within the normal range.

Conclusions

This study suggests that adolescents with anorexia nervosa have elevated levels of autism spectrum traits, obsessive-compulsive symptoms, and a small proportion fulfil diagnostic criteria for a probable autism spectrum disorder. These traits did not appear to be familial. This comorbidity has been associated with a poorer prognosis. Therefore, adaptation of treatment for this subgroup may be warranted.

Trial registration

Controlled-trials.com: ISRCTN83003225. Registered on 29 September 2011.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2014

Molecular Autism 1/2014 Zur Ausgabe


 

Neu in den Fachgebieten Neurologie und Psychiatrie

Meistgelesene Bücher in der Neurologie & Psychiatrie

  • 2016 | Buch

    Neurologie

    Das Lehrbuch vermittelt Ihnen das gesamte Neurologie-Prüfungswissen für Ihr Medizinstudium und bereitet auch junge Assistenzärzte durch detailliertes Fachwissen optimal auf die Praxis vor. Die komplett überarbeitete Auflage enthält sechs neue, interdisziplinäre Kapitel.

    Herausgeber:
    Werner Hacke
  • 2016 | Buch

    Komplikationen in der Neurologie

    Das Buch schildert Ereignisse im Rahmen der Neuromedizin, die während der Diagnostik und Therapie neurologischer Erkrankungen und Symptome auftreten können. Die Fallbeispiele sensibilisieren Sie für mögliche Risikofaktoren, um das Auftreten solcher Komplikationen zu vermeiden.

    Herausgeber:
    Frank Block
  • 2017 | Buch

    Facharztwissen Psychiatrie, Psychosomatik und Psychotherapie

    Leitsymptome, Untersuchungsmethoden, Krankheitsbilder, Notfälle & Co. – mit der Neuauflage des "Facharztwissens" sind Sie auf die Facharztprüfung in Psychiatrie und Psychotherapie optimal vorbereitet. In dieser 2. Auflage sind die Kapitel zu psychosomatischen Störungen deutlich ausgebaut.

    Herausgeber:
    Prof. Dr. Dr. Frank Schneider
  • 2019 | Buch

    Kompendium der Psychotherapie

    Für Ärzte und Psychologen

    Dieses Werk wendet sich an Ärzte und Psychologen, die an psychiatrischen und psychosomatischen Kliniken oder an Psychotherapeutischen Ausbildungsinstituten arbeiten und in den vorhandenen Lehrbüchern der Psychotherapie den Brückenschlag zur …

    Herausgeber:
    Tilo Kircher
Bildnachweise