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Erschienen in: Comparative Clinical Pathology 5/2011

01.10.2011 | Original Article

Anti-diabetic effect of orally administered Otostegia persica extract on streptozotocin diabetic rats

verfasst von: Mohammad Reza Ebrahimpoor, Zabihollah Khaksar, Ali Noorafshan

Erschienen in: Comparative Clinical Pathology | Ausgabe 5/2011

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Abstract

Anti-diabetic effect of the alcoholic extract of Otostegia persica was investigated on 40 streptozotocin diabetic rats in four equal groups. Animals in the first group did not receive any extract and acted as a control for the other groups. Rats in group II, III, and IV received a daily oral dose of O. persica extract at 200, 350, and 500 mg/kg, respectively, for 3 weeks. Blood glucose level was estimated three times a day (8:00 and 11:00 am and 5:30 pm) in all groups. Statistical analysis of the results by t test showed that the extract produced a dose-dependent decrease in the blood glucose level especially in the fourth group (p < 0.0001) in comparison the control group. Thus, study indicates that O. persica has a strong anti-diabetic action and can decrease blood glucose levels.
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Metadaten
Titel
Anti-diabetic effect of orally administered Otostegia persica extract on streptozotocin diabetic rats
verfasst von
Mohammad Reza Ebrahimpoor
Zabihollah Khaksar
Ali Noorafshan
Publikationsdatum
01.10.2011
Verlag
Springer-Verlag
Erschienen in
Comparative Clinical Pathology / Ausgabe 5/2011
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-010-1030-5

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