Erschienen in:
01.08.2015 | New Therapies for Cardiovascular Disease (KW Mahaffey, Section Editor)
Antiplatelet Therapy During PCI for Patients with Stable Angina and Atrial Fibrillation
verfasst von:
Amjid Iqbal, Fatima Rodriguez, Henrik Schirmer
Erschienen in:
Current Cardiology Reports
|
Ausgabe 8/2015
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Abstract
The pharmacological treatment options for anticoagulation in patients with atrial fibrillation (Afib) have increased with the introduction of novel oral anticoagulants, compared with earlier times, when vitamin K antagonist was the drug of choice. As they age, many Afib patients require percutaneous coronary intervention (PCI), necessitating antiplatelet medication in addition to anticoagulation therapy. Choosing the appropriate combination and duration of anticoagulation and antiplatelet therapies may be challenging in stable coronary artery disease (CAD) and even more complicated during and after coronary intervention with the introduction of additional antithrombotic drugs. In this article, we review the scientific basis for the recent guidelines for anticoagulation and antithrombotic therapy in patients with Afib and stable CAD before, during, and after elective PCI.