Background
Methods
Study design and site
Study population and sampling
Study procedure
Measures
Data analysis
Ethical considerations
Results
Socio-demographic characteristics
Characteristics | Total sample N = 622 N (%) | CIA N = 399 N (%) | BIA N = 223 N (%) | p-value |
---|---|---|---|---|
Mean age in years (SD)
#
| 17.7(1.60) | 17.4(1.80) | 18.2(1.01) |
< 0.01
|
Gender*
| ||||
Male | 338 (54.3) | 218 (54.6) | 120 (53.8) | 0.843 |
Female | 284 (45.7) | 181 (45.4) | 103 (46.2) | |
Religion*
| ||||
Christianity | 496(80.0) | 318(79.9) | 178(80.2) | 0.907 |
Other | 31(5.0) | 19(4.8) | 12(5.4) | |
No religion | 93(15.0) | 61(15.3) | 32(14.4) | |
Highest level of education*
| ||||
Junior high school and below | 372(60.8) | 239 (60.7) | 133(61.0) | 0.932 |
Senior High school and above | 240(39.2) | 155(39.3) | 85(39.0) | |
Perceived social support from family*
| ||||
Poor | 344(55.7) | 224(56.6) | 120(54.1) | 0.547 |
Good | 274(44.3) | 172(43.2) | 102(45.9) | |
Types of caregivers*
| ||||
Single parent and others | 402(64.6) | 253(63.4) | 149(66.8) | 0.394 |
Both parents | 220(35.4) | 146(36.6) | 74(33.2) |
The pattern of adherence in the ALWHIV
Characteristics | Total sample N = 622 N (%) | CIA N = 399 N (%) | BIA N = 223 N (%) | p-value |
---|---|---|---|---|
Support/counselling from care providers*
| ||||
Poor | 162(26.2) | 105(26.4) | 57(25.8) | 0.859 |
Good | 456(73.8) | 292(73.6) | 164(74.2) | |
Clinic attendance*
| ||||
Poor | 60(9.7) | 33(8.3) | 27(12.2) | 0.116 |
Good | 558(90.3) | 364(91.7) | 194(87.8) | |
Acceptance of status*
| ||||
Difficulty in accepting status | 194(33.8) | 85(23.9) | 109(50.0) |
< 0.01
|
Has accepted status | 380(66.2) | 271(76.1) | 109(50.0) | |
Knows HIV status
@
| ||||
yes | 545(88.0) | 324(81.4) | 221(100) |
< 0.01
|
No | 74(12.0) | 74(18.6) | - | |
Family member with HIV*
| ||||
Yes | 406(66.8) | 288(74.4) | 118(53.4) |
< 0.01
|
No | 110(18.1) | 44(11.4) | 66(29.9) | |
Don’t know | 92(15.1) | 55(14.2) | 37(16.7) | |
Felt worse when taking meds*
| ||||
Yes | 29(4.7) | 17(4.3) | 12(5.4) | 0.521 |
No | 591(95.3) | 381(95.7) | 210(94.6) | |
Depression*
| ||||
Present | 147(23.6) | 82(20.6) | 65(29.1) |
0.016
|
Absent | 475(76.4) | 317(79.4) | 158(70.9) | |
Alcohol Use Disorder*
| ||||
Present | 110(17.7) | 61(15.3) | 49(22.0) |
0.036
|
Absent | 512(82.3) | 338(84.7) | 174(78.0) | |
Adherence score (SD)
#
| 87.9(17.3) | 89.6(17.1) | 85.0(17.2) |
0.002
|
Viral load (SD)
#
| 2104.3 (13306.4) | 1302.7 (29664.4) | 3552.5 (21387.0) |
0.048
|
Cognitive screening score (SD)
#
| 10.17(1.67) | 9.81(1.82) | 10.80(1.09) |
< 0.01
|
The association of depression, cognitive impairment, and alcohol use disorder with non-adherence
Characteristics | N/n | COR | 95% CI. |
P
| AOR | 95% CI. | ||
---|---|---|---|---|---|---|---|---|
lower | Upper | Lower | Upper | |||||
Level of education*
|
394
| |||||||
Junior high school and below | 239 | 0.74 | 0.49 | 1.13 | 0.286 | 0.77 | 0.47 | 1.25 |
Paternal orphaned*
|
389
| |||||||
Yes | 76 | 0.48 | 0.27 | 0.84 | 0.701 | 1.38 | 0.27 | 7.12 |
Maternal orphaned
|
399
| |||||||
Yes | 124 | 0.78 | 0.50 | 1.22 | 0.680 | 0.85 | 0.40 | 1.81 |
Double orphan
|
399
| |||||||
Yes | 76 | 1.83 | 1.06 | 3.18 | 0.113 | 4.52 | 0.69 | 29.3 |
Types of caregivers
|
399
| |||||||
Single parent or others | 253 | 1.28 | 0.84 | 1.95 | 0.055 | 1.70 | 0.99 | 2.91 |
Felt healthy when taking med
|
399
| |||||||
Yes | 96 | 4.182 | 2.58 | 6.79 |
< 0.01
| 3.68 | 2.11 | 6.41 |
Felt worse when taking meds*
|
398
| |||||||
Yes | 17 | 4.09 | 1.41 | 11.9 | 0.224 | 2.09 | 0.64 | 6.81 |
Cognitive screening score
|
399
| |||||||
Lower score | 145 | 3.14 | 2.05 | 4.80 |
< 0.01
| 2.86 | 1.77 | 4.64 |
Depression
|
399
| |||||||
Present | 82 | 3.42 | 2.06 | 5.66 |
0.001
| 2.69 | 1.48 | 4.90 |
Characteristics | N/n | COR | 95% CI. |
P
| AOR | 95% CI. | ||
---|---|---|---|---|---|---|---|---|
Lower | Upper | Lower | Upper | |||||
Gender
|
223
| |||||||
Male | 120 | 0.57 | 0.33 | 0.97 | 0.093 | 0.59 | 0.32 | 1.09 |
Maternal orphaned
|
223
| |||||||
Yes | 48 | 1.50 | 0.78 | 2.90 | 0.244 | 1.54 | 0.75 | 3.16 |
Felt healthy when taking med*
|
222
| |||||||
Yes | 71 | 1.98 | 1.104 | 3.57 |
0.024
| 2.10 | 1.10 | 4.00 |
Alcohol Use Disorder
|
223
| |||||||
Present | 49 | 2.22 | 1.13 | 4.36 |
0.014
| 2.58 | 1.21 | 5.49 |
Depression
|
223
| |||||||
Present | 65 | 3.21 | 1.70 | 6.05 |
0.009
| 2.55 | 1.27 | 5.16 |
HIV status*
|
218
| |||||||
Difficulty in accepting status | 109 | 2.67 | 1.54 | 4.62 |
0.002
| 2.54 | 1.41 | 4.56 |