Background
Methods
Patients
Study design
Assessments
Statistical analysis
Results
Patients
Aripiprazole lauroxil treatment outcomes
Exploratory efficacy outcomes
Caregiver- and patient-reported outcomes
Baseline | Week 9 | Week 25 | |
---|---|---|---|
All patients (observed cases) | |||
Total score, patients, n | 88 | 53b | 43c |
Mean (SD) | 40.8 (14.2) | 32.7 (13.1) | 31.8 (11.9) |
Change from baseline, mean (SD) | – | −8.4 (10.2) | −8.9 (12.4) |
Patients who completed 25 weeks of treatmentd | |||
Total score, patients, n | 42 | 40 | 42 |
Mean (SD) | 40.6 (15.1) | 33.1 (13.8) | 31.7 (12.0) |
Change from baseline, mean (SD) | – | −8.0 (9.8) | −8.9 (12.4) |
Week 5 | Week 13 | Week 25 | |
---|---|---|---|
All patients (observed cases) | |||
Total score, n | 73 | 65 | 57 |
Mean (SD) | 48.7 (11.2) | 48.7 (10.1) | 49.0 (11.5) |
Satisfaction with Medication, n | 67 | 63 | 52 |
Mean (SD) | 3.9 (1.0) | 3.8 (1.0) | 3.8 (0.9) |
Overall Life Satisfaction, n | 73 | 65 | 57 |
Mean (SD) | 3.9 (1.0) | 3.7 (0.9) | 3.8 (1.0) |
Patients who completed 25 weeks of treatmentb | |||
Total score, n | 57 | 57 | 57 |
Mean (SD) | 49.2 (10.3) | 49.1 (9.3) | 49.0 (11.5) |
Satisfaction with Medication, n | 52 | 55 | 52 |
Mean (SD) | 4.0 (0.8) | 3.9 (0.9) | 3.8 (0.9) |
Overall Life Satisfaction, n | 57 | 57 | 57 |
Mean (SD) | 3.8 (0.9) | 3.7 (0.9) | 3.8 (1.0) |
Paliperidone palmitate treatment outcomes
Exploratory efficacy outcomes
Caregiver- and patient-reported outcomes
Baseline | Week 9 | Week 25 | |
---|---|---|---|
All patients (observed cases) | |||
Total score, patients, n | 96 | 46 | 33 |
Mean (SD) | 38.9 (14.4) | 31.3 (13.0) | 31.5 (13.0) |
Change from baseline, mean (SD) | – | −8.8 (11.9) | −9.2 (14.6) |
Patients who completed 25 weeks of treatmentb | |||
Total score, patients, n | 33 | 31 | 33 |
Mean (SD) | 40.6 (13.5) | 30.6 (13.2) | 31.5 (13.0) |
Change from baseline, mean (SD) | – | −9.9 (13.2) | −9.2 (14.6) |
Week 5 | Week 13 | Week 25 | |
---|---|---|---|
All patients (observed cases) | |||
Total score, n | 67 | 59 | 45 |
Mean (SD) | 49.6 (10.1) | 48.0 (12.8) | 49.6 (12.3) |
Satisfaction with Medication, n | 55 | 52 | 44 |
Mean (SD) | 3.6 (0.9) | 3.7 (1.1) | 3.6 (1.2) |
Overall Life Satisfaction, n | 67 | 59 | 45 |
Mean (SD) | 3.9 (1.0) | 3.5 (1.2) | 3.6 (1.2) |
Patients who completed 25 weeks of treatmentb | |||
Total score, n | 45 | 45 | 45 |
Mean (SD)a | 49.2 (10.3) | 47.8 (13.5) | 49.6 (12.3) |
Satisfaction with Medication, n | 36 | 41 | 44 |
Mean (SD) | 3.6 (0.9) | 3.7 (1.2) | 3.6 (1.1) |
Overall Life Satisfaction, n | 45 | 45 | 45 |
Mean (SD) | 3.8 (1.0) | 3.5 (1.3) | 3.6 (1.2) |