Erschienen in:
16.10.2018 | ASO Author Reflections
ASO Author Reflections: Axillary Surgery for Node-Positive Mastectomy Patients
verfasst von:
Sara Gaines, MD, Katharine Yao, MD
Erschienen in:
Annals of Surgical Oncology
|
Sonderheft 3/2018
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Excerpt
Prior to 2010, a tumor-positive sentinel node indicated the need for a complete axillary lymph node dissection (ALND) in lumpectomy patients. The American College of Surgeons Oncology Group’s Z0011 trial shifted this paradigm by demonstrating no difference in 5-year disease-free survival between patients with clinically node-negative disease who had one to two positive sentinel lymph nodes (SN) and who underwent sentinel node biopsy (SNB) alone or SNB followed by ALND.
1 Likewise, the IBCSG and AMAROS trials also demonstrated similar findings, but all three of these studies were lacking any large number of mastectomy patients.
2,
3 In 2013, the National Cancer Data Base added a variable known as ‘scope of regional lymph node surgery’, which specifies the type and sequence of nodal surgery. Using this variable, we examined the patterns of care for the management of the axilla in mastectomy patients with early-stage, pathology node-positive disease, and how the type of axillary surgery impacted the use of post-mastectomy chest wall radiation (PMRT). …
