Erschienen in:
23.10.2018 | ASO Author Reflections
ASO Author Reflections: Systemic Inflammatory Markers in Pancreatic Neuroendocrine Tumors
verfasst von:
Apostolos Gaitanidis, MD, Dhaval Patel, MD, Electron Kebebew, MD, FACS
Erschienen in:
Annals of Surgical Oncology
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Sonderheft 3/2018
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Excerpt
Pancreatic neuroendocrine tumors (PNETs) are rare tumors, exhibiting highly variable biological behavior, ranging from indolent to aggressive. Predicting the biological behavior of PNETs is difficult. Prognostic factors currently utilized to predict tumor progression, recurrence, or survival include tumor grade, presence of lymph node metastasis, and perineural invasion. In the majority of cases, these factors are available only after histologic examination. Therefore, novel biomarkers are needed to improve prognostic assessment in patients with PNETs to optimize management and treatment. The prognostic value of several markers of systemic inflammatory response has been suggested by several studies for different types of cancer, including neuroendocrine tumors.
1 The aim of this study is to examine the potential prognostic role of markers of systemic inflammatory response in patients with PNETs. …