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01.12.2007 | Original Article

Association between thyroid autoimmunity and fibromyalgic disease severity

verfasst von: Laura Bazzichi, Alessandra Rossi, Tiziana Giuliano, Francesca De Feo, Camillo Giacomelli, Arianna Consensi, Antonio Ciapparelli, Giorgio Consoli, Liliana Dell’Osso, Stefano Bombardieri

Erschienen in: Clinical Rheumatology | Ausgabe 12/2007

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Abstract

Our objectives were to investigate thyroid abnormalities and autoimmunity in 120 patients affected by fibromyalgia (FM) and to study their relationships with clinical data and symptoms. Thyroid assessment by means of antithyroglobulin antibodies, antithyroid peroxidase antibodies, free triiodo–thyronine, free thyroxine, and thyroid stimulating hormone analyses was carried out. The clinical parameters “Fibromyalgia Impact Questionnaire”, pain, tender points, fatigue, and other symptoms, and the presence of depression or anxiety disorders were evaluated. The basal thyroid hormone levels of FM patients were in the normal range, while 41% of the patients had at least one thyroid antibody. Patients with thyroid autoimmunity showed a higher percentage of dry eyes, burning, or pain with urination, allodynia, blurred vision, and sore throat. Correlations found between thyroid autoimmunity and age or with the presence of depression or anxiety disorders were not significant. However, in the cohort of post-menopausal patients, the frequency of thyroid autoimmunity was higher with respect to pre-menopausal patients. In conclusion, autoimmune thyroiditis is present in an elevated percentage of FM patients, and it has been associated with the presence of typical symptoms of the disease.

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Titel: Association between thyroid autoimmunity and fibromyalgic disease severity
verfasst von: Laura Bazzichi
Alessandra Rossi
Tiziana Giuliano
Francesca De Feo
Camillo Giacomelli
Arianna Consensi
Antonio Ciapparelli
Giorgio Consoli
Liliana Dell’Osso
Stefano Bombardieri
Publikationsdatum: 01.12.2007
Verlag: Springer London
Erschienen in: Clinical Rheumatology / Ausgabe 12/2007
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-007-0636-8

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