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Pediatric Nephrology

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01.09.2007 | Brief Report

Atypical p-ANCA is not a poor prognostic marker in Postinfectious Glomerulonephritis

verfasst von: Aoife Waters, Valerie Langlois, Paul Thorner, Denis Geary

Erschienen in: Pediatric Nephrology | Ausgabe 9/2007

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Abstract

Postinfectious glomerulonephritis (PIGN) most commonly follows streptococcal infection. Antineutrophil cytoplasmic antibodies (ANCA) are characteristically negative in PIGN. We report on five cases who had positive atypical pANCA at presentation. The outcome was typical of other cases of PIGN with complete resolution of the glomerulonephritis in all five patients. Atypical pANCA occurs in a number of inflammatory conditions and antigenic targets may include proteins other than myeloperoxidase or proteinase 3. The presence of atypical p-ANCA does not indicate a poor prognosis.

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Titel: Atypical p-ANCA is not a poor prognostic marker in Postinfectious Glomerulonephritis
verfasst von: Aoife Waters
Valerie Langlois
Paul Thorner
Denis Geary
Publikationsdatum: 01.09.2007
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 9/2007
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-007-0495-1

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Atypical p-ANCA is not a poor prognostic marker in Postinfectious Glomerulonephritis

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