Skip to main content
Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 1/2019

30.11.2018 | Original Article

Autologous Fat Augmentation in Post Type III Cordectomy Patients

verfasst von: Sachin Gandhi, Shashank Gupta, Nilanjan Bhowmick, Aniketh Pandurangi, Vrushali Desai

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Ausgabe 1/2019

Einloggen, um Zugang zu erhalten

Abstract

Neocord formation after Type III cordectomy is insufficient for complete glottic closure due to scarring and soft tissue deficit. This study evaluates the role of autologous fat injection (AFI) in phonosurgical management of patients who have previously undergone Type III cordectomy for early glottic cancer. Data was collected from hospital records of patients who underwent AFI after previously undergoing Type III cordectomy. A minimum duration of 6 months post-cordectomy was maintained before fat injection. Trans-oral injection was performed at a single site. Pre-operative voice evaluation was done using VHI, GRBAS scale and MDVP software. Post-operative evaluation was done at 6 weeks. 21 out of 62 post-Type III cordectomy patients chose to undergo fat augmentation and were included in the study. A comparison of pre-operative and 6 months post-operative AFI voice analysis showed a significant improvement in VHI, all parameters of GRBAS scale, and improvement in Jitter, Shimmer, SPI and NHR. There was a decrease in fundamental frequency but this was not statistically significant. AFI is an effective procedure for surgical voice rehabilitation of patients who have undergone Type III cordectomy for early laryngeal cancer.
Literatur
1.
Zurück zum Zitat Johansen LV, Grau C, Overgaard J (2003) Laryngeal carcinoma. Multivariate analysis of prognostic factors in 1252 consecutive patients treated with primary radiotherapy. Acta Oncol 42:771–778CrossRefPubMed Johansen LV, Grau C, Overgaard J (2003) Laryngeal carcinoma. Multivariate analysis of prognostic factors in 1252 consecutive patients treated with primary radiotherapy. Acta Oncol 42:771–778CrossRefPubMed
2.
Zurück zum Zitat Jørgensen K, Godballe C, Hansen O, Bastholt L (2002) Cancer of the larynx. Treatment results after primary radiotherapy with salvage surgery in a series of 1005 patients. Acta Oncol 41:69–76CrossRefPubMed Jørgensen K, Godballe C, Hansen O, Bastholt L (2002) Cancer of the larynx. Treatment results after primary radiotherapy with salvage surgery in a series of 1005 patients. Acta Oncol 41:69–76CrossRefPubMed
3.
Zurück zum Zitat Laccourreye O, Muscatello L, Laccourreye L, Naudo P, Brasnu D, Weinstein G (1997) Supracricoid partial laryngectomy with cricohyoidoepiglottopexy for “early” glottic carcinoma classified as T1-T2N0 invading the anterior commissure. Am J Otolaryngol 18:385–390CrossRefPubMed Laccourreye O, Muscatello L, Laccourreye L, Naudo P, Brasnu D, Weinstein G (1997) Supracricoid partial laryngectomy with cricohyoidoepiglottopexy for “early” glottic carcinoma classified as T1-T2N0 invading the anterior commissure. Am J Otolaryngol 18:385–390CrossRefPubMed
4.
Zurück zum Zitat Laccourreye O, Laccourreye L, Garcia D, Gutierrez-Fonseca R, Brasnu D, Weinstein G (2000) Vertical partial laryngectomy versus supracricoid partial laryngectomy for selected carcinomas of the true vocal cord classified as T2N0. Ann Otol Rhinol Laryngol 109:965–971CrossRefPubMed Laccourreye O, Laccourreye L, Garcia D, Gutierrez-Fonseca R, Brasnu D, Weinstein G (2000) Vertical partial laryngectomy versus supracricoid partial laryngectomy for selected carcinomas of the true vocal cord classified as T2N0. Ann Otol Rhinol Laryngol 109:965–971CrossRefPubMed
5.
Zurück zum Zitat Peretti G, Nicolai P, Redaelli De Zinis LO, Berlucchi M, Bazzana T, Bertoni F, Antonelli AR (2000) Endoscopic CO2 laser excision for Tis, T1, and T2 glottic carcinomas: cure rates and prognostic factors. Otolaryngol Head Neck Surg 123:124–131CrossRefPubMed Peretti G, Nicolai P, Redaelli De Zinis LO, Berlucchi M, Bazzana T, Bertoni F, Antonelli AR (2000) Endoscopic CO2 laser excision for Tis, T1, and T2 glottic carcinomas: cure rates and prognostic factors. Otolaryngol Head Neck Surg 123:124–131CrossRefPubMed
6.
Zurück zum Zitat Spector JG, Sessions DG, Chao KS, Haughey BH, Hanson JM, Simpson JR, Perez CA (1999) Stage I (T1N0M0) squamous cell carcinoma of the laryngeal glottis: therapeutic results and voice preservation. Head Neck 21:707–717CrossRefPubMed Spector JG, Sessions DG, Chao KS, Haughey BH, Hanson JM, Simpson JR, Perez CA (1999) Stage I (T1N0M0) squamous cell carcinoma of the laryngeal glottis: therapeutic results and voice preservation. Head Neck 21:707–717CrossRefPubMed
7.
Zurück zum Zitat Steiner W, Ambrosch P (2001) Endoscopic laser surgery of the upper aerodigestive tract. With special emphasis on cancer surgery. Thieme, Stuttgart Steiner W, Ambrosch P (2001) Endoscopic laser surgery of the upper aerodigestive tract. With special emphasis on cancer surgery. Thieme, Stuttgart
8.
Zurück zum Zitat Zeitels SM (1996) Phonomicrosurgical treatment of early glottic cancer and carcinoma in situ. Am J Surg 172:704–709CrossRefPubMed Zeitels SM (1996) Phonomicrosurgical treatment of early glottic cancer and carcinoma in situ. Am J Surg 172:704–709CrossRefPubMed
9.
Zurück zum Zitat Remacle M, Eckel HE, Antonelli AR, Brasnu D, Chevalier D, Friedrich G, Olofsson J, Rudert HH, Thumfart W, de Vincentiis M, Wustrow TP (2000) Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society. Eur Arch Otorhinolaryngol 257:227–231CrossRefPubMed Remacle M, Eckel HE, Antonelli AR, Brasnu D, Chevalier D, Friedrich G, Olofsson J, Rudert HH, Thumfart W, de Vincentiis M, Wustrow TP (2000) Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society. Eur Arch Otorhinolaryngol 257:227–231CrossRefPubMed
10.
Zurück zum Zitat Hirano M (1981) Clinical examination of voice. In: Arnold GE, Winckel F, Wyke BD (eds) Disorders of human communication. Springer, New York, pp 81–84 Hirano M (1981) Clinical examination of voice. In: Arnold GE, Winckel F, Wyke BD (eds) Disorders of human communication. Springer, New York, pp 81–84
11.
Zurück zum Zitat Jacobson BH, Johnson A, Grywalski C, Silbergleit A, Jacobson G, Benninger MS, Newman CW (1997) The voice handicap index (VHI): development and validation. Am J Speech Lang Pathol 6:66–70CrossRef Jacobson BH, Johnson A, Grywalski C, Silbergleit A, Jacobson G, Benninger MS, Newman CW (1997) The voice handicap index (VHI): development and validation. Am J Speech Lang Pathol 6:66–70CrossRef
12.
Zurück zum Zitat Bruennings W (1911) Uber eine neue behandlungsmethode der rekurrensslahmung. Ver Deutsch Laryng 18:93–151 Bruennings W (1911) Uber eine neue behandlungsmethode der rekurrensslahmung. Ver Deutsch Laryng 18:93–151
13.
Zurück zum Zitat Shaw GY, Szewczyk MA, Searle J, Woodroof J (1997) Autologous fat injection into the vocal folds: technical considerations and long-term follow-up. Laryngoscope 107(2):177–186CrossRefPubMed Shaw GY, Szewczyk MA, Searle J, Woodroof J (1997) Autologous fat injection into the vocal folds: technical considerations and long-term follow-up. Laryngoscope 107(2):177–186CrossRefPubMed
14.
Zurück zum Zitat Mallur PS, Rosen CA (2010) Vocal fold injection: review of indications, techniques, and materials for augmentation. Clin Exp Otorhinolaryngol 3(4):177–182CrossRefPubMedPubMedCentral Mallur PS, Rosen CA (2010) Vocal fold injection: review of indications, techniques, and materials for augmentation. Clin Exp Otorhinolaryngol 3(4):177–182CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Mikaelian DO, Lowry LD, Sataloff RT (1991) Lipoinjection for unilateral vocal cord paralysis. Laryngoscope 101(5):465–468CrossRefPubMed Mikaelian DO, Lowry LD, Sataloff RT (1991) Lipoinjection for unilateral vocal cord paralysis. Laryngoscope 101(5):465–468CrossRefPubMed
16.
Zurück zum Zitat Sanderson JD, Simpson CB (2009) Laryngeal complications after lipoinjection for vocal fold augmentation. Laryngoscope 119:1652–1657CrossRefPubMed Sanderson JD, Simpson CB (2009) Laryngeal complications after lipoinjection for vocal fold augmentation. Laryngoscope 119:1652–1657CrossRefPubMed
17.
Zurück zum Zitat Hsiung MW, Woo P, Minasian A et al (2000) Fat augmentation for glottic insufficiency. Laryngoscope 110:1026–1033CrossRefPubMed Hsiung MW, Woo P, Minasian A et al (2000) Fat augmentation for glottic insufficiency. Laryngoscope 110:1026–1033CrossRefPubMed
18.
Zurück zum Zitat Jacobson BH, Johnson A, Grywalski C, Silbergleit A, Jacobson G, Benninger MS et al (1997) The Voice Handicap Index (VHI): development and validation. Am J Speech Lang Pathol 6(3):66–70CrossRef Jacobson BH, Johnson A, Grywalski C, Silbergleit A, Jacobson G, Benninger MS et al (1997) The Voice Handicap Index (VHI): development and validation. Am J Speech Lang Pathol 6(3):66–70CrossRef
19.
Zurück zum Zitat Sittel C, Friedrich G, Zorowka P, Eckel HE (2002) Surgical voice rehabilitation after laser surgery for glottic carcinoma. Ann Otol Rhinol Laryngol 111:493–499CrossRefPubMed Sittel C, Friedrich G, Zorowka P, Eckel HE (2002) Surgical voice rehabilitation after laser surgery for glottic carcinoma. Ann Otol Rhinol Laryngol 111:493–499CrossRefPubMed
20.
Zurück zum Zitat Koufmann JA (1986) The endoscopic management of early squamous carcinoma of the vocal cord with the carbon dioxide surgical laser: clinical experience and a proposed subclassification. Otolaryngol Head Neck Surg 95:531–537CrossRef Koufmann JA (1986) The endoscopic management of early squamous carcinoma of the vocal cord with the carbon dioxide surgical laser: clinical experience and a proposed subclassification. Otolaryngol Head Neck Surg 95:531–537CrossRef
21.
Zurück zum Zitat Hirano S, Bless DM, Rousseau B, Welham N, Montequin D, Chan RW, Ford CN (2004) Prevention of vocal fold scarring by topical injection of hepatocyte growth factor in a rabbit model. Laryngoscope 114:548–556CrossRefPubMed Hirano S, Bless DM, Rousseau B, Welham N, Montequin D, Chan RW, Ford CN (2004) Prevention of vocal fold scarring by topical injection of hepatocyte growth factor in a rabbit model. Laryngoscope 114:548–556CrossRefPubMed
22.
Zurück zum Zitat Remacle M, Lawson G, Hedayat A, Trussart C, Jamart J (2001) Medialization framework surgery for voice improvement after endoscopic cordectomy. Eur Arch Otorhinolaryngol 258:267–271CrossRef Remacle M, Lawson G, Hedayat A, Trussart C, Jamart J (2001) Medialization framework surgery for voice improvement after endoscopic cordectomy. Eur Arch Otorhinolaryngol 258:267–271CrossRef
23.
Zurück zum Zitat Peretti G, Piazza C, Bolzoni A, Mensi MC, Rossini M, Parrinello G, Shapshay SM, AR Antonelli (2004) Analysis of recurrences in 322 Tis, T1, or T2 glottic carcinomas treated by carbon dioxide laser. Ann Otol Rhinol Laryngol 113:853–858CrossRefPubMed Peretti G, Piazza C, Bolzoni A, Mensi MC, Rossini M, Parrinello G, Shapshay SM, AR Antonelli (2004) Analysis of recurrences in 322 Tis, T1, or T2 glottic carcinomas treated by carbon dioxide laser. Ann Otol Rhinol Laryngol 113:853–858CrossRefPubMed
24.
Zurück zum Zitat Villaret AB, Piazza C, Zinis LOR, Cattaneo A, Cocco D, Peretti G (2007) Phonosurgery after endoscopic cordectomies. I. Primary intracordal autologous fat injection after transmuscular resection: preliminary results. Eur Arch Otorhinolaryngol 264:1179–1184CrossRef Villaret AB, Piazza C, Zinis LOR, Cattaneo A, Cocco D, Peretti G (2007) Phonosurgery after endoscopic cordectomies. I. Primary intracordal autologous fat injection after transmuscular resection: preliminary results. Eur Arch Otorhinolaryngol 264:1179–1184CrossRef
25.
Zurück zum Zitat Guven M, Suoglu Y, Kiyak E, Demir D (2006) Autologous fat augmentation for voice and swallow improvement after cordectomy. ORL 68:164–169CrossRefPubMed Guven M, Suoglu Y, Kiyak E, Demir D (2006) Autologous fat augmentation for voice and swallow improvement after cordectomy. ORL 68:164–169CrossRefPubMed
Metadaten
Titel
Autologous Fat Augmentation in Post Type III Cordectomy Patients
verfasst von
Sachin Gandhi
Shashank Gupta
Nilanjan Bhowmick
Aniketh Pandurangi
Vrushali Desai
Publikationsdatum
30.11.2018
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe 1/2019
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-018-1543-9

Weitere Artikel der Ausgabe 1/2019

Indian Journal of Otolaryngology and Head & Neck Surgery 1/2019 Zur Ausgabe

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

HNO-Op. auch mit über 90?

16.04.2024 HNO-Chirurgie Nachrichten

Mit Blick auf das Risiko für Komplikationen nach elektiven Eingriffen im HNO-Bereich scheint das Alter der Patienten kein ausschlaggebender Faktor zu sein. Entscheidend ist offenbar, wie fit die Betroffenen tatsächlich sind.

Intrakapsuläre Tonsillektomie gewinnt an Boden

16.04.2024 Tonsillektomie Nachrichten

Gegenüber der vollständigen Entfernung der Gaumenmandeln hat die intrakapsuläre Tonsillektomie einige Vorteile, wie HNO-Fachleute aus den USA hervorheben. Sie haben die aktuelle Literatur zu dem Verfahren gesichtet.

Bilateraler Hörsturz hat eine schlechte Prognose

15.04.2024 Hörsturz Nachrichten

Die Mehrzahl der Menschen mit Hörsturz ist einseitig betroffen, doch auch ein beidseitiger Hörsturz ist möglich. Wie häufig solche Fälle sind und wie sich ihr Verlauf darstellt, hat eine HNO-Expertenrunde aus den USA untersucht.

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.