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Current Osteoporosis Reports
Erschienen in: Current Osteoporosis Reports 6/2019

16.11.2019 | Kidney and Bone (I Salusky and T Nickolas, Section Editors)

Bone Health in Glomerular Kidney Disease

verfasst von: Dorey A. Glenn, Michelle R. Denburg

Erschienen in: Current Osteoporosis Reports | Ausgabe 6/2019

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Abstract

Purpose of Review

To summarize the literature regarding alterations in bone health in patients with glomerular kidney disease and highlight areas in need of additional investigation.

Recent Findings

There is mounting evidence that children and adults with glomerular conditions, with or without compromised kidney function, comprise a distinct subgroup of patients with unique risk factors for altered bone health.

Summary

Patients with glomerular kidney disease are exposed to both disease-related and treatment-related factors that affect bone structure and function. In addition to chronic kidney disease–related risk factors for impaired bone health, high rates of exposure to osteotoxic medications, varying degrees of systemic inflammation, and altered vitamin D metabolism may contribute to compromised bone health in individuals with glomerular disease. Further study is needed to better understand these risk factors and the complex interaction between the immune system and bone cells in glomerular disease.
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Metadaten
Titel
Bone Health in Glomerular Kidney Disease
verfasst von
Dorey A. Glenn
Michelle R. Denburg
Publikationsdatum
16.11.2019
Verlag
Springer US
Erschienen in
Current Osteoporosis Reports / Ausgabe 6/2019
Print ISSN: 1544-1873
Elektronische ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-019-00531-z

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