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Pediatric Nephrology

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01.03.2013 | Educational Review

Treatment of steroid-resistant nephrotic syndrome in children: new guidelines from KDIGO

verfasst von: Rebecca M. Lombel, Elisabeth M. Hodson, Debbie S. Gipson

Erschienen in: Pediatric Nephrology | Ausgabe 3/2013

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Abstract

Kidney Disease: Improving Global Outcomes (KDIGO) recently published the clinical practice guideline on glomerulonephritis (GN) to assist the practitioner caring for patients with GN. Chapter 4 of the guideline focuses on managing children aged 1–18 years with steroid-resistant nephrotic syndrome (SRNS), defined by an inability to achieve complete remission with corticosteroid therapy. Guideline development followed a thorough evidence review, and management recommendations and suggestions were based on the best available evidence. Limitations of the evidence, including the paucity of large-scale randomized controlled trials, are discussed. This article provides both the guideline recommendations and a brief review of relevant treatment trials related to each recommendation. This précis serves as a summary of the complete guidelines recently published.

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Titel: Treatment of steroid-resistant nephrotic syndrome in children: new guidelines from KDIGO
verfasst von: Rebecca M. Lombel
Elisabeth M. Hodson
Debbie S. Gipson
Publikationsdatum: 01.03.2013
Verlag: Springer-Verlag
Erschienen in: Pediatric Nephrology / Ausgabe 3/2013
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-012-2304-8

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