Ausgabe 4/2014
Inhalt (30 Artikel)
Association of phosphatase and tensin homolog low and phosphatidylinositol 3-kinase catalytic subunit alpha gene mutations on outcome in human epidermal growth factor receptor 2-positive metastatic breast cancer patients treated with first-line lapatinib plus paclitaxel or paclitaxel alone
Binghe Xu, Zhongzhen Guan, Zhenzhou Shen, Zhongshen Tong, Zefei Jiang, Junlan Yang, Michelle DeSilvio, Mark Russo, Meggan Leigh, Catherine Ellis
Nestin positively regulates the Wnt/β-catenin pathway and the proliferation, survival and invasiveness of breast cancer stem cells
Zuowei Zhao, Ping Lu, Hao Zhang, Huanming Xu, Ningning Gao, Man Li, Caigang Liu
The influence of tamoxifen on normal mouse mammary gland homeostasis
Mona Shehata, Renée van Amerongen, Amber L Zeeman, Rajshekhar R Giraddi, John Stingl
Tumor homologous recombination deficiency assays: another step closer to clinical application?
Shane R Stecklein, Priyanka Sharma
A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype
Qing Cheng, Jeffrey T Chang, William R Gwin, Jun Zhu, Stefan Ambs, Joseph Geradts, H Kim Lyerly
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression
Jing-Yi Chen, Chien-Feng Li, Cheng-Chin Kuo, Kelvin K Tsai, Ming-Feng Hou, Wen-Chun Hung
Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer
Fahimeh Falahi, Michel van Kruchten, Nadine Martinet, Geke Hospers, Marianne G Rots
Mammographic features associated with interval breast cancers in screening programs
Norman F Boyd, Ella Huszti, Olga Melnichouk, Lisa J Martin, Greg Hislop, Anna Chiarelli, Martin J Yaffe, Salomon Minkin
Physical activity and telomere length in early stage breast cancer survivors
Sheila N Garland, Brad Johnson, Christina Palmer, Rebecca M Speck, Michelle Donelson, Sharon X Xie, Angela DeMichele, Jun J Mao
Dual HER2 blockade: preclinical and clinical data
Tejal A Patel, Bhuvanesh Dave, Angel A Rodriguez, Jenny C Chang, Edith A Perez, Gerardo Colon-Otero
A joint analysis of metabolomics and genetics of breast cancer
Xiaohu Tang, Chao-Chieh Lin, Ivan Spasojevic, Edwin S Iversen, Jen-Tsan Chi, Jeffrey R Marks
Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells
Sravanth K Hindupur, Sai A Balaji, Meera Saxena, Shubham Pandey, Gopalkrishnashetty Sreenivasmurthy Sravan, Namrata Heda, M Vijaya Kumar, Geetashree Mukherjee, Devaveena Dey, Annapoorni Rangarajan
PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors
Brian D Lehmann, Joshua A Bauer, Johanna M Schafer, Christopher S Pendleton, Luojia Tang, Kimberly C Johnson, Xi Chen, Justin M Balko, Henry Gómez, Carlos L Arteaga, Gordon B Mills, Melinda E Sanders, Jennifer A Pietenpol
The dynamic range of circulating tumor DNA in metastatic breast cancer
Maryam Heidary, Martina Auer, Peter Ulz, Ellen Heitzer, Edgar Petru, Christin Gasch, Sabine Riethdorf, Oliver Mauermann, Ingrid Lafer, Gunda Pristauz, Sigurd Lax, Klaus Pantel, Jochen B Geigl, Michael R Speicher
Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease
Aaron J Knox, Allison L Scaling, Mauricio P Pinto, Brian S Bliesner, James M Haughian, Hany A Abdel-Hafiz, Kathryn B Horwitz
Evaluation of functional genetic variants at 6q25.1 and risk of breast cancer in a Chinese population
Yanru Wang, Yisha He, Zhenzhen Qin, Yue Jiang, Guangfu Jin, Hongxia Ma, Juncheng Dai, Jiaping Chen, Zhibin Hu, Xiaoxiang Guan, Hongbing Shen
Risk factors for self-reported arm lymphedema among female breast cancer survivors: a prospective cohort study
Kayo Togawa, Huiyan Ma, Jane Sullivan-Halley, Marian L Neuhouser, Ikuyo Imayama, Kathy B Baumgartner, Ashley Wilder Smith, Catherine M Alfano, Anne McTiernan, Rachel Ballard-Barbash, Leslie Bernstein
Relationships between computer-extracted mammographic texture pattern features and BRCA1/2mutation status: a cross-sectional study
Gretchen L Gierach, Hui Li, Jennifer T Loud, Mark H Greene, Catherine K Chow, Li Lan, Sheila A Prindiville, Jennifer Eng-Wong, Peter W Soballe, Claudia Giambartolomei, Phuong L Mai, Claudia E Galbo, Kathryn Nichols, Kathleen A Calzone, Olufunmilayo I Olopade, Mitchell H Gail, Maryellen L Giger
uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies
Michael J Duffy, Patricia M McGowan, Nadia Harbeck, Christoph Thomssen, Manfred Schmitt
Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification, using an independent prospective breast cancer cohort and external patient populations
Dong-Yu Wang, Susan J Done, David R Mc Cready, Wey L Leong
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
Patrick C O’Leary, Marta Terrile, Malgorzata Bajor, Pawel Gaj, Bryan T Hennessy, Gordon B Mills, Agnieszka Zagozdzon, Darran P O’Connor, Donal J Brennan, Kate Connor, Jane Li, Ana Maria Gonzalez-Angulo, Han-Dong Sun, Jian-Xin Pu, Fredrik Pontén, Mathias Uhlén, Karin Jirström, Dominika A Nowis, John P Crown, Radoslaw Zagozdzon, William M Gallagher
MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers
Raisa Krutilina, Wenlin Sun, Aarti Sethuraman, Martin Brown, Tiffany N Seagroves, Lawrence M Pfeffer, Tatyana Ignatova, Meiyun Fan
Developing a new generation of breast cancer clinical gene expression tests
Zuzana Kos, Torsten O Nielsen
Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer
Bojana Jovanović, J Scott Beeler, Michael W Pickup, Anna Chytil, Agnieszka E Gorska, William J Ashby, Brian D Lehmann, Andries Zijlstra, Jennifer A Pietenpol, Harold L Moses
Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients
Ryuji Takahashi, Uhi Toh, Nobutaka Iwakuma, Miki Takenaka, Hiroko Otsuka, Mina Furukawa, Teruhiko Fujii, Naoko Seki, Akihiko Kawahara, Masayoshi Kage, Satoko Matsueda, Yoshito Akagi, Akira Yamada, Kyogo Itoh, Tetsuro Sasada
Evaluating the predictive value of biomarkers for efficacy outcomes in response to pertuzumab- and trastuzumab-based therapy: an exploratory analysis of the TRYPHAENA study
Andreas Schneeweiss, Stephen Chia, Roberto Hegg, Christoph Tausch, Rahul Deb, Jayantha Ratnayake, Virginia McNally, Graham Ross, Astrid Kiermaier, Javier Cortés
Molecular effects of lapatinib in patients with HER2 positive ductal carcinoma in situ
Laura G Estévez, Ana Suarez-Gauthier, Elena García, Cristina Miró, Isabel Calvo, María Fernández-Abad, Mercedes Herrero, Manuel Marcos, Cristina Márquez, Fernando Lopez Ríos, Sofía Perea, Manuel Hidalgo
Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo
Daniel Klevebring, Gustaf Rosin, Ran Ma, Johan Lindberg, Kamila Czene, Juha Kere, Irma Fredriksson, Jonas Bergh, Johan Hartman
Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation
Zhaojia Wu, Siqi Shen, Zhiling Zhang, Weiwei Zhang, Wei Xiao