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Breast Cancer Research and Treatment

Ausgabe 1/2024

Inhalt (20 Artikel)

Review

Association between prediabetes and breast cancer: a comprehensive meta-analysis

Praneeth Reddy Keesari, Akhil Jain, Narendranath Reddy Ganampet, Guna Sowmya Durga Subhasri, Samuel Edusa, Zainab Muslehuddin, Nyein Wint Yee Theik, Spandana Palisetti, Divya Salibindla, Pritika Singh Manaktala, Rupak Desai

Open Access Preclinical study

Association of clinicopathologic and molecular factors with the occurrence of positive margins in breast cancer

Anupama Praveen Kumar, Diego Vicente, Jianfang Liu, Praveen-Kumar Raj-Kumar, Brenda Deyarmin, Xiaoying Lin, Craig D. Shriver, Hai Hu

Preclinical study

Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients

Mieke C. Zwager, Iris Holt-Kedde, Hetty Timmer-Bosscha, Geertruida H. de Bock, Paul M. N. Werker, Carolien P. Schröder, Bert van der Vegt, Marlous Arjaans

Open Access Clinical trial

Analysis of data from the PALOMA-3 trial confirms the efficacy of palbociclib and offers alternatives for novel assessment of clinical trials

Celine Yeh, Mengxi Zhou, Neil Bapodra, Dawn Hershman, Edward Espinal, Marina Moran, Maria Rivero, Antonio Tito Fojo, Susan E. Bates

Clinical trial

Randomized adaptive selection trial of cryotherapy, compression therapy, and placebo to prevent taxane-induced peripheral neuropathy in patients with breast cancer

Melissa K. Accordino, Shing Lee, Cheng Shiun Leu, Bruce Levin, Meghna S. Trivedi, Katherine D. Crew, Kevin Kalinsky, Rohit Raghunathan, Khadija Faheem, Erik Harden, Alessandra Taboada, Beatriz Desanti de Oliveira, Elisabeth Larson, Lauren Franks, Erin Honan, Cynthia Law, Dawn L. Hershman

Open Access Epidemiology

The effects of contemporary treatment of DCIS on the risk of developing an ipsilateral invasive Breast cancer (iIBC) in the Dutch population

Sena Alaeikhanehshir, Renée S.J.M. Schmitz, Alexandra W. van den Belt-Dusebout, Frederieke H. van Duijnhoven, Ellen Verschuur, Maartje van Seijen, Michael Schaapveld, Esther H. Lips, Jelle Wesseling

Epidemiology

Association between body mass index and outcomes after autologous breast reconstruction: a nationwide inpatient database study in Japan

Ryo Karakawa, Takaaki Konishi, Hidehiko Yoshimatsu, Yohei Hashimoto, Hiroki Matsui, Kiyohide Fushimi, Tomoyuki Yano, Hideo Yasunaga

Open Access Epidemiology

Incidence and risk factors of hypothyroidism after treatment for early breast cancer: a population-based cohort study

Evangelos Digkas, Daniel Robert Smith, Anna-Karin Wennstig, Alexios Matikas, Eva Tegnelius, Antonios Valachis

Epidemiology

Impact of HER2-low status for patients with early-stage breast cancer and non-pCR after neoadjuvant chemotherapy: a National Cancer Database Analysis

Huiyue Li, Jennifer K. Plichta, Kan Li, Yizi Jin, Samantha M. Thomas, Fei Ma, Li Tang, Qingyi Wei, You-Wen He, Qichen Chen, Yuanyuan Guo, Yueping Liu, Jian Zhang, Sheng Luo

Epidemiology

Patterns of chemotherapy receipt among patients with hormone receptor-positive, HER2-negative breast cancer

Linnea T. Olsson, Alina M. Hamilton, Sarah C. Van Alsten, Jennifer L. Lund, Til Stürmer, Hazel B. Nichols, Katherine E. Reeder-Hayes, Melissa A. Troester

Epidemiology

Superparamagnetic iron oxide (SPIO) for axillary mapping in patients with ductal carcinoma in situ undergoing mastectomy: single-institution experience

Jamin Kweku Addae, Raeshell Sharawn Sweeting, Ingrid Marie Meszoely, Rachel Louise McCaffrey, Rondi Marie Kauffmann, Mark Carlton Kelley, Ana Magdalena Grau, Kelly Hewitt

Original Laboratory Investigation

A randomized phase II study of metronomic cyclophosphamide and methotrexate (CM) with or without bevacizumab in patients with advanced breast cancer

Erica L. Mayer, Nabihah Tayob, Siyang Ren, Jennifer J. Savoie, David R. Spigel, Howard A. Burris III, Paula D. Ryan, Lyndsay N. Harris, Eric P. Winer, Harold J. Burstein

Open Access Original Laboratory Investigation

Restoring microRNA-34a overcomes acquired drug resistance and disease progression in human breast cancer cell lines via suppressing the ABCC1 gene

Shaymaa M. M. Yahya, Heba K. Nabih, Ghada H. Elsayed, Shimaa Ibrahim Abdelmenym Mohamed, Asmaa M. Elfiky, Sohair M. Salem

Original Laboratory Investigation

Breast cancers in monoallelic MUTYH germline mutation carriers have clinicopathological features overlapping with those in BRCA1 germline mutation carriers

Aysenur Keske, Paul Weisman, Monica Ospina-Romero, Prachi Raut, Kelcy Smith-Simmer, Anna L. Zakas, Christopher Flynn, Jin Xu

Original Laboratory Investigation

FTO is a major genetic link between breast cancer, obesity, and diabetes

Morteza Gholami

Open Access Original Laboratory Investigation

Clinicopathologic and genetic analysis of invasive breast carcinomas in women with germline CHEK2 variants

Christopher J. Schwartz, Nikka Khorsandi, Amie Blanco, Rita A. Mukhtar, Yunn-Yi Chen, Gregor Krings

Brief Communication

Prevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study

Deanna Blansky, Norin Ansari, Lucy Gao, Ethan S. Sokol, Smruthy Sivakumar, Richard S.P. Huang, Maureen Pelletier, Mia Levy, Dean Pavlick, Natalie Danziger, Jeffrey S Ross, Maryam Lustberg, Mariya Rozenblit

Letter to the Editor

Northern origin of the BRCA2 c.5286 T > G founder allele

Grigory A. Yanus, Anna P. Sokolenko, Evgeny N. Imyanitov

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Update Onkologie

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