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Breast Cancer Research and Treatment

Ausgabe 3/2023

Inhalt (20 Artikel)

Open Access Preclinical study

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Open Access Preclinical study

Is de-escalation of treatment by omission of radiotherapy associated with fear of cancer recurrence in women with early breast cancer? An exploratory study

Lesley Stafford, Michelle Sinclair, Phyllis Butow, Janemary Hughes, Allan Park, Leslie Gilham, Allison Rose, G. Bruce Mann

Open Access Clinical trial

Plasma cell-free tumor DNA, PIK3CA and TP53 mutations predicted inferior endocrine-based treatment outcome in endocrine receptor-positive metastatic breast cancer

Tom Wei-Wu Chen, Wen Hsiao, Ming-Shen Dai, Ching-Hung Lin, Dwan-Ying Chang, I-Chun Chen, Ming-Yang Wang, Shu-Han Chang, Shu-Min Huang, Ann-Lii Cheng, Ko-Wen Wu, Kien Thiam Tan, Yen-Shen Lu

Clinical trial

Frequent upregulation of HER2 protein in hormone-receptor-positive HER2-negative breast cancer after short-term neoadjuvant endocrine therapy

Lubna N. Chaudhary, Julie M. Jorns, Yunguang Sun, Yee Chung Cheng, Sailaja Kamaraju, John Burfeind, Mary Beth Gonyo, Amanda L. Kong, Caitlin Patten, Tina Yen, Chandler S. Cortina, Ebony Carson, Nedra Johnson, Carmen Bergom, Shirng-Wern Tsaih, Anjishnu Banerjee, Yu Wang, Inna Chervoneva, Elizabeth Weil, Christopher R. Chitambar, Hallgeir Rui

Clinical trial

Analysis of prognosis in different subtypes of invasive lobular carcinoma using the Japanese National Cancer Database-Breast Cancer Registry

Yayoi Adachi, Sota Asaga, Hiraku Kumamaru, Naoko Kinugawa, Yasuaki Sagara, Naoki Niikura, Hiromitsu Jinno, Shigehira Saji, Masakazu Toi

Clinical trial

Phase II trial of biweekly administration with eribulin after three cycles of induction therapy in hormone receptor-positive, HER2-negative metastatic breast cancer (JACCRO BC-03)

Kokoro Kobayashi, Norikazu Masuda, Toshiro Mizuno, Kayo Miura, Yutaka Tokuda, Tetsuhiro Yoshinami, Hidetoshi Kawaguchi, Shoichiro Ohtani, Toshiaki Saeki, Masakazu Toi, Masahiro Takeuchi, Yoshinori Ito

Clinical trial

Prediction of nipple involvement in breast cancer after neoadjuvant chemotherapy: Should we rely on breast MRI to preserve the nipple?

M. Umit Ugurlu, Onur Bugdayci, Ahmet Akmercan, Handan Kaya, Tugba Akin Telli, Haldun Akoglu, Bahadir M. Gulluoglu

Epidemiology

The dynamics of HER2-low expression during breast cancer progression

Sarah Anderson, Brooke Baxter Bartow, Gene P. Siegal, Xiao Huang, Shi Wei

Epidemiology

Longitudinal adherence to breast cancer surveillance following cancer genetic testing in an integrated health care system

Sarah Knerr, Boya Guo, Karen J. Wernli, Kathleen F. Mittendorf, Heather Spencer Feigelson, Marian J. Gilmore, Gail P. Jarvik, Tia L. Kauffman, Erin Keast, Elizabeth G. Liles, Frances L. Lynch, Kristin R. Muessig, Sonia Okuyama, David L. Veenstra, Jamilyn M. Zepp, Benjamin S. Wilfond, Beth Devine, Katrina A. B. Goddard

Open Access Epidemiology

The impact of geriatric characteristics and comorbidities on distant metastases and other cause mortality in older women with non-metastatic breast cancer treated with primary endocrine therapy

M. E.C. Waaijer, A. A. Lemij, A. Z. de Boer, E. Bastiaannet, F. van den Bos, M. G.M. Derks, J. R. Kroep, G. J. Liefers, J. E.A. Portielje, N. A. de Glas

Open Access Epidemiology

Sexual health in long-term breast cancer survivors: a comparison with female population controls from the HUNT study

Solveig K. Smedsland, Kathrine F. Vandraas, Ragnhild S. Falk, Julie Horn, Randi J. Reidunsdatter, Cecilie E. Kiserud, Alv A. Dahl, Mette Brekke, Kristin V. Reinertsen

Original Laboratory Investigation

Treatments for breast cancer in men: late effects and impact on quality of life

Jorge Avila, Beth Herrick, Deanna J. Attai, José Pablo Leone

Original Laboratory Investigation

SGLT1 as an adverse prognostic factor in invasive ductal carcinoma of the breast

Satoko Tsunokake, Erina Iwabuchi, Yasuhiro Miki, Ayako Kanai, Yoshiaki Onodera, Hironobu Sasano, Takanori Ishida, Takashi Suzuki

Original Laboratory Investigation

FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer

Chen Chen, Leiguang Ye, Jinfeng Yi, Tang Liu, Zhigao Li

Open Access Original Laboratory Investigation

Oestrogen receptor low positive breast cancer: associations with prognosis

Anette H. Skjervold, Marit Valla, Anna M. Bofin

Original Laboratory Investigation

Clinical characteristics and treatment outcomes of invasive ductal and lobular carcinoma: analyses of 54,832 taiwan cancer registry index cases

Bo-Fang Chen, Yi-Fang Tsai, Pei-Ju Lien, Yen-Shu Lin, Chin-Jung Feng, Yen-Jen Chen, Han-Fang Cheng, Ling-Ming Tseng, Chi-Cheng Huang

Original Laboratory Investigation

Dimethyl fumarate inhibits ZNF217 and can be beneficial in a subset of estrogen receptor positive breast cancers

Tanu Sharma, Yuanjin Zhang, Alexandra Zigrossi, Benjamin F. Cravatt, Irida Kastrati

Original Laboratory Investigation

Plasma apolipoprotein M predicts overall survival in metastatic breast cancer patients

Axel Muendlein, Christine Heinzle, Eva Maria Brandtner, Andreas Leiherer, Kathrin Geiger, Stella Gaenger, Heinz Drexel, Tobias Dechow, Thomas Decker

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

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