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Breast Cancer Research and Treatment

Ausgabe 2/2013

Inhalt (22 Artikel)

Open Access Preclinical Study

Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes

Aleix Prat, Olga Karginova, Joel S. Parker, Cheng Fan, Xiaping He, Lisa Bixby, J. Chuck Harrell, Erick Roman, Barbara Adamo, Melissa Troester, Charles M. Perou

Preclinical study

Genomic profiling of histological special types of breast cancer

Hugo M. Horlings, Britta Weigelt, Eric M. Anderson, Maryou B. Lambros, Alan Mackay, Rachael Natrajan, Charlotte K. Y. Ng, Felipe C. Geyer, Marc J. van de Vijver, Jorge S. Reis-Filho

Open Access Preclinical study

Cure of metastatic growth of EMT6 tumor cells in mice following manipulation of CD200:CD200R signaling

Reginald M. Gorczynski, Zhiqi Chen, Ismat Khatri, Anna Podnos, Kai Yu

Preclinical Study

Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue

Myriam Vilasco, Laudine Communal, Justine Hugon-Rodin, Frédérique Penault-Llorca, Najat Mourra, Zherui Wu, Patricia Forgez, Anne Gompel

Preclinical Study

RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial–mesenchymal transition

Chonggao Yin, Hongli Li, Baogang Zhang, Yuqing Liu, Guohua Lu, Shijun Lu, Lei Sun, Yueliang Qi, Xiaolong Li, Weiyi Chen

Preclinical study

Expression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in breast cancers

Julia Y. S. Tsang, Ying Kin Kwok, Kit Wing Chan, Yun-Bi Ni, Wan Ning Vanessa Chow, Kwok Fai Lau, Mu-Min Shao, Siu Ki Chan, Puay-Hoon Tan, Gary M. Tse

Preclinical Study

The prognostic value of apoptotic and proliferative markers in breast cancer

Charla C. Engels, Francesca Ruberta, Esther M. de Kruijf, Gabi W. van Pelt, Vincent T. H. B. M. Smit, Gerrit Jan Liefers, Tomoko Matsushima, Masaki Shibayama, Hideki Ishihara, Cornelis J. H. van de Velde, Peter J. K. Kuppen

Preclinical study

Upregulated WAVE3 expression is essential for TGF-β-mediated EMT and metastasis of triple-negative breast cancer cells

Molly A. Taylor, Gangarao Davuluri, Jenny G. Parvani, Barbara J. Schiemann, Michael K. Wendt, Edward F. Plow, William P. Schiemann, Khalid Sossey-Alaoui

Preclinical study

Tumor immune subtypes distinguish tumor subclasses with clinical implications in breast cancer patients

Esther M. de Kruijf, Charla C. Engels, Willemien van de Water, Esther Bastiaannet, Vincent T. H. B. M. Smit, Cornelis J. H. van de Velde, Gerrit Jan Liefers, Peter J. K. Kuppen

Open Access Preclinical Study

Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns

Sabrina A. Bardowell, Joel Parker, Cheng Fan, Jamie Crandell, Charles M. Perou, Theresa Swift-Scanlan

Clinical Trial

Phase II randomized trial of weekly and every-3-week ixabepilone in metastatic breast cancer patients

John W. Smith II, Svetislava Vukelja, Amy Rabe, Nicole Wentworth-Hartung, Nicholas Koutrelakos, Spencer H. Shao, Thomas Whittaker, Yunfei Wang, Lina Asmar, Diane Opatt McDowell, Pralay Mukhopadhyay, Joyce O’Shaughnessy

Clinical Trial

A clinical trial of lovastatin for modification of biomarkers associated with breast cancer risk

Shaveta Vinayak, Erich J. Schwartz, Kristin Jensen, Jafi Lipson, Elizabeth Alli, Lisa McPherson, Adrian M. Fernandez, Vandana B. Sharma, Ashley Staton, Meredith A. Mills, Elizabeth A. Schackmann, Melinda L. Telli, Ani Kardashian, James M. Ford, Allison W. Kurian

Clinical trial

A phase I study of lapatinib with whole brain radiotherapy in patients with Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer brain metastases

Nancy U. Lin, Rachel A. Freedman, Naren Ramakrishna, Jerry Younger, Anna Maria Storniolo, Jennifer R. Bellon, Steven E. Come, Rebecca S. Gelman, Gordon J. Harris, Mark A. Henderson, Shannon M. MacDonald, Anand Mahadevan, Emily Eisenberg, Jennifer A. Ligibel, Erica L. Mayer, Beverly Moy, April F. Eichler, Eric P. Winer

Clinical trial

Preliminary results of centralized HER2 testing in ductal carcinoma in situ (DCIS): NSABP B-43

Kalliopi P. Siziopikou, Stewart J. Anderson, Melody A. Cobleigh, Thomas B. Julian, Douglas W. Arthur, Ping Zheng, Eleftherios P. Mamounas, Eduardo R. Pajon, Robert J. Behrens, Janice F. Eakle, Nick C. Leasure, James N. Atkins, Jonathan A. Polikoff, Thomas E. Seay, Worta J. McCaskill-Stevens, Rachel Rabinovitch, Joseph P. Costantino, Norman Wolmark

Epidemiology

Barriers to physical activity and healthy eating in young breast cancer survivors: modifiable risk factors and associations with body mass index

Emily E. Ventura, Patricia A. Ganz, Julienne E. Bower, Liana Abascal, Laura Petersen, Annette L. Stanton, Catherine M. Crespi

Epidemiology

Aromatase inhibitor therapy and hair loss among breast cancer survivors

Lisa Gallicchio, Carla Calhoun, Kathy J. Helzlsouer

Brief Report

Is there a role for routine screening MRI in women with LCIS?

Tari A. King, Shirin Muhsen, Sujata Patil, Starr Koslow, Sabine Oskar, Anna Park, Mary Morrogh, Rita A. Sakr, Monica Morrow

Brief Report

Impact of SERM adherence on treatment effect: International Breast Cancer Study Group Trials 13-93 and 14-93

Olivia Pagani, Shari Gelber, Marco Colleoni, Karen N. Price, Edda Simoncini

Open Access Letter to the Editor

Closing an on-going clinical trial: when is it betrayal of participants?

Cynthia Chauhan, Mary Lou Smith

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Update Onkologie

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