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Breast Cancer Research and Treatment

Ausgabe 2/2021

Inhalt (30 Artikel)

Review

Breast cancer patients with a negative axillary ultrasound may have clinically significant nodal metastasis

Stephen Keelan, Anna Heeney, Eithne Downey, Aisling Hegarty, Trudi Roche, Colm Power, Neasa Ni Mhuircheartaigh, Deirdre Duke, Jennifer Kerr, Niamh Hambly, Arnold Hill

Review

New horizons in imaging and surgical assessment of breast cancer lymph node metastasis

Firouzeh Arjmandi, Ann Mootz, Deborah Farr, Sangeetha Reddy, Basak Dogan

Review

Benefit of adjuvant chemotherapy in patients with special histology subtypes of triple-negative breast cancer: a systematic review

D. Trapani, F. Giugliano, J. Uliano, V. A. A. Zia, A. Marra, G. Viale, E. Ferraro, A. Esposito, C. Criscitiello, P. D’amico, G. Curigliano

Preclinical study

SETD2 alterations and histone H3K36 trimethylation in phyllodes tumor of breast

Julia Y. Tsang, Sui-Ting Lai, Yun-Bi Ni, Yan Shao, Ivan K. Poon, Johnny S. Kwan, Chit Chow, Ka-Ho Shea, Gary M. Tse

Preclinical study

NSDHL promotes triple-negative breast cancer metastasis through the TGFβ signaling pathway and cholesterol biosynthesis

Mengting Chen, Yang Zhao, Xueli Yang, Yuanyuan Zhao, Qiqi Liu, Yang Liu, Yifeng Hou, Hefen Sun, Wei Jin

Open Access Preclinical study

Efficacy of fluvastatin and aspirin for prevention of hormonally insensitive breast cancer

Anjana Bhardwaj, Matthew D. Embury, Raniv D. Rojo, Constance Albarracin, Isabelle Bedrosian

Preclinical study

FASN inhibition as a potential treatment for endocrine-resistant breast cancer

Aleksandra Gruslova, Bryan McClellan, Henriette U. Balinda, Suryavathi Viswanadhapalli, Victoria Alers, Gangadhara R. Sareddy, Tim Huang, Michael Garcia, Linda deGraffenried, Ratna K. Vadlamudi, Andrew J. Brenner

Preclinical study

Circulating tumor cells, circulating tumor DNA, and disease characteristics in young women with metastatic breast cancer

Ami N. Shah, Kristen J. Carroll, Lorenzo Gerratana, Chenyu Lin, Andrew A. Davis, Qiang Zhang, Saya Jacob, Brian Finkelman, Youbin Zhang, Wenen Qiang, Paolo D’Amico, Carolina Reduzzi, William J. Gradishar, Amir Behdad, Massimo Cristofanilli

Open Access Clinical trial

The impact of high-intensity interval exercise training on NK-cell function and circulating myokines for breast cancer prevention among women at high risk for breast cancer

Adriana M. Coletta, Nadia H. Agha, Forrest L. Baker, Grace M. Niemiro, Preteesh L. Mylabathula, Abenaa M. Brewster, Therese B. Bevers, Enrique Fuentes-Mattei, Karen Basen-Engquist, Susan C. Gilchrist, Richard J. Simpson

Clinical trial

A propensity score-matched comparison of recurrence outcomes after immediate implant vs autologous flap reconstruction in patients receiving neoadjuvant chemotherapy for breast cancer

Zhen-Yu Wu, Hyun Ho Han, Hee Jeong Kim, Jong Won Lee, Il Yong Chung, Jisun Kim, Sae Byul Lee, Byung-Ho Son, Jin Sup Eom, Jae Ho Jung, Sung- Bae Kim, Gyungyub Gong, Hak Hee Kim, Sei -Hyun Ahn, BeomSeok Ko

Open Access Clinical trial

The impact of age on patient-reported outcomes after oncoplastic versus conventional breast cancer surgery

M. Ritter, B. M. Ling, I. Oberhauser, G. Montagna, L. Zehnpfennig, J. Lévy, S. D. Soysal, L. López Castrezana, M. Müller, F. D. Schwab, C. Kurzeder, M. Haug, W. P. Weber, E. A. Kappos

Clinical trial

Prognostic value of p53 expression in hormone receptor-positive and human epidermal growth factor receptor 2-negative breast cancer patients receiving neoadjuvant chemotherapy

Loai Saleh Albinsaad, Jisun Kim, Il Yong Chung, Beom Seok Ko, Hee Jeong Kim, Jong Won Lee, Byung Ho Son, Sei-Hyun Ahn, Sae Byul Lee

Open Access Clinical trial

Subcutaneous trastuzumab with pertuzumab and docetaxel in HER2-positive metastatic breast cancer: Final analysis of MetaPHER, a phase IIIb single-arm safety study

Sherko Kuemmel, Carlo A. Tondini, Jacinta Abraham, Zbigniew Nowecki, Bartosz Itrych, Erika Hitre, Bogusława Karaszewska, Alejandro Juárez-Ramiro, Flavia Morales-Vásquez, Jose Manuel Pérez-García, Servando Cardona-Huerta, Estefania Monturus, Marco Sequi, Eleonora Restuccia, Mark Benyunes, Miguel Martín

Clinical trial

Adjuvant bisphosphonate use in patients with early stage breast cancer: a physician survey

Sharon McGee, Mashari Alzahrani, Lisa Vandermeer, Katherine Cole, Gail Larocque, Arif Awan, Brian Hutton, Gregory Pond, Deanna Saunders, Mark Clemons

Clinical trial

Examining the effect of obesity-associated gene variants on breast cancer survivors in a randomized weight loss intervention

ThaiHien Nguyen, Melinda L. Irwin, Andrew T. Dewan, Brenda Cartmel, Maura Harrigan, Leah M. Ferrucci, Tara Sanft, Fangyong Li, Lingeng Lu, Yasmmyn D. Salinas

Open Access Clinical trial

Repeat breast-conserving treatment of ipsilateral breast cancer recurrence: a nationwide survey amongst breast surgeons and radiation oncologists in the Netherlands

Coco J. E. F. Walstra, Robert-Jan Schipper, Yvonne E. van Riet, Peter-Paul G. van der Toorn, Marjolein L. Smidt, Maurice J. C. vd Sangen, Adri C. Voogd, Grard A. P. Nieuwenhuijzen

Epidemiology

Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers

Neda Stjepanovic, Jan Lubinski, Pal Moller, Susan Randall Armel, William D. Foulkes, Nadine Tung, Susan L. Neuhausen, Joanne Kotsopoulos, Ping Sun, Sophie Sun, Andrea Eisen, Steven A. Narod, Leigha Senter, Charis Eng Fergus Couch, Robert Fruscio, Jeffrey N. Weitzel, Olufunmilayo Olopade, Christian F. Singer, Tuya Pal, Tomasz Huzarski, Cezary Cybulski, Kevin Sweet, Dana Zakalik, Marie Wood, Wendy McKinnon, Christine Elser, Georgia Wiesner, Eitan Friedman, Wendy Meschino, Carrie Snyder, Kelly Metcalfe, Aletta Poll, Ellen Warner, Raymond Kim, Rochelle Demsky, Peter Ainsworth, Linda Steele, Howard Saal, Kim Serfas, Seema Panchal, Carey A. Cullinane, Robert E. Reilly, Joanne L. Blum, Ava Kwong, Daniel Rayson, Teresa Ramón y Cajal, Jeffrey Dungan, Rinat Yerushalmi, Ophira Ginsburg, Intan Schraeder, Stephanie Cohen, Edmond LemireLemire, Stefania Zovato, Antonella Rastelli, Jacek Gronwald, Jeanna McCuaig, Beth Karlan, Louise Bordeleau

Epidemiology

Early postoperative outcomes in implant, pedicled, and free flap reconstruction for breast cancer: an analysis of 23,834 patients from the ACS-NSQIP datasets

Murad J. Karadsheh, Richard Tyrell, Mengying Deng, Brian L. Egleston, James C. Krupp, M. Shuja Shafqat, Sameer A. Patel

Open Access Epidemiology

Diagnostic value of radiomics and machine learning with dynamic contrast-enhanced magnetic resonance imaging for patients with atypical ductal hyperplasia in predicting malignant upgrade

Roberto Lo Gullo, Kerri Vincenti, Carolina Rossi Saccarelli, Peter Gibbs, Michael J. Fox, Isaac Daimiel, Danny F. Martinez, Maxine S. Jochelson, Elizabeth A. Morris, Jeffrey S. Reiner, Katja Pinker

Epidemiology

Comparison of the performance of four staging systems in determining the prognosis of breast cancer among women undergoing neoadjuvant chemotherapy

Isabella Cristina Santos Soares, Marcelo Adeodato Bello, Anke Bergmann, Luiz Claudio Santos Thuler

Epidemiology

Exploring provider- and practice-level drivers of cost-consciousness in breast cancer reconstruction—secondary analysis of a survey of the American Society of Plastic Surgeons

Clifford C. Sheckter, Oluseyi Aliu, Chad Bailey, Jun Liu, Jesse C. Selber, Charles E. Butler, Anaeze C. Offodile II

Open Access Epidemiology

The increasing importance of histologic grading in tailoring adjuvant systemic therapy in 30,843 breast cancer patients

C. van Dooijeweert, I. O. Baas, I. A. G. Deckers, S. Siesling, P. J. van Diest, E. van der Wall

Wo hapert es noch bei der Umsetzung der POMGAT-Leitlinie?

03.05.2024 DCK 2024 Kongressbericht

Seit November 2023 gibt es evidenzbasierte Empfehlungen zum perioperativen Management bei gastrointestinalen Tumoren (POMGAT) auf S3-Niveau. Vieles wird schon entsprechend der Empfehlungen durchgeführt. Wo es im Alltag noch hapert, zeigt eine Umfrage in einem Klinikverbund.

Bestrahlung nach Prostatektomie: mehr Schaden als Nutzen?

02.05.2024 Prostatakarzinom Nachrichten

Eine adjuvante Radiotherapie nach radikaler Prostata-Op. bringt den Betroffenen wahrscheinlich keinen Vorteil. Im Gegenteil: Durch die Bestrahlung steigt offenbar das Risiko für Harn- und Stuhlinkontinenz.

ASS schützt nicht vor Brustkrebsrezidiven

02.05.2024 Mammakarzinom Nachrichten

Nützt nichts und ist vielleicht sogar schädlich: In einer Phase-3-Studie konnten täglich 300 mg ASS keine Brustkrebsrezidive bei Frauen vermeiden, die ein hohes Risiko für eine Tumorrückkehr aufwiesen. Tendenziell traten unter ASS sogar häufiger Rezidive auf als unter Placebo.

CUP-Syndrom: Künstliche Intelligenz kann Primärtumor finden

30.04.2024 Künstliche Intelligenz Nachrichten

Krebserkrankungen unbekannten Ursprungs (CUP) sind eine diagnostische Herausforderung. KI-Systeme können Pathologen dabei unterstützen, zytologische Bilder zu interpretieren, um den Primärtumor zu lokalisieren.

Update Onkologie

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