Erschienen in:
01.06.2014 | Pros and Cons in Endocrine Practice
Cabergoline treatment in acromegaly: cons
verfasst von:
Leandro Kasuki, Leonardo Vieira Neto, Mônica R. Gadelha
Erschienen in:
Endocrine
|
Ausgabe 2/2014
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Abstract
Many options are available for the treatment of acromegaly, including surgery, radiotherapy, and medical treatment. Cabergoline (CAB), a dopamine agonist with high affinity for dopamine receptor type 2, has been used both in monotherapy and in conjunction with somatostatin analogs (SSAs). Although it is administered orally and has a relatively lower-cost in comparison with SSAs, few studies have demonstrated its usefulness, there is a lack of randomized-controlled trials and other drugs (SSAs and pegvisomant) with more data in the literature are available; these issues are the main drawbacks of adopting CAB for the treatment of acromegaly.