Ausgabe 4/2014
Inhalt (24 Artikel)
Should EGFR mutations be tested in advanced lung squamous cell carcinomas to guide frontline treatment?
Chao-Hua Chiu, Teh-Ying Chou, Chi-Lu Chiang, Chun-Ming Tsai
Pharmacogenetics of adjuvant breast cancer treatment with cyclophosphamide, epirubicin and 5-fluorouracil
David Jamieson, Jo Lee, Nicola Cresti, Rosanna Jackson, Melanie Griffin, Julieanne Sludden, Mark Verrill, Alan V. Boddy
Risk and outcomes of chemotherapy-induced diarrhea (CID) among patients with colorectal cancer receiving multi-cycle chemotherapy
Dorothy M. Keefe, Linda S. Elting, Hoang T. Nguyen, Steven M. Grunberg, Giuseppe Aprile, Antony Bonaventura, Sudarsha Selva-Nayagam, Andrea Barsevick, Bogda Koczwara, Stephen T. Sonis
Long progression-free survival with first-line paclitaxel plus platinum is associated with improved response and progression-free survival with second-line docetaxel in advanced non-small-cell lung cancer
Eleazar Omar Macedo-Pérez, Vicente Morales-Oyarvide, Víctor Osvaldo Mendoza-García, Yuzmiren Dorantes-Gallareta, Diana Flores-Estrada, Oscar Arrieta
Treatment of resistant metastatic melanoma using sequential epigenetic therapy (decitabine and panobinostat) combined with chemotherapy (temozolomide)
Chang Xia, Roberto Leon-Ferre, Douglas Laux, Jeremy Deutsch, Brian J. Smith, Melanie Frees, Mohammed Milhem
Phase I study of adjuvant gemcitabine or S-1 in patients with biliary tract cancers undergoing major hepatectomy: KHBO1003 study
Shogo Kobayashi, Hiroaki Nagano, Daisuke Sakai, Hidetoshi Eguchi, Etsuro Hatano, Masashi Kanai, Satoru Seo, Kojiro Taura, Yutaka Fujiwara, Tetsuo Ajiki, Shigekazu Takemura, Shoji Kubo, Hiroaki Yanagimoto, Hideyoshi Toyokawa, Akihito Tsuji, Hiroaki Terajima, Satoshi Morita, Tatsuya Ioka
Chemotherapy-associated steatohepatitis induced by irinotecan: a novel animal model
Marcelo Leite Vieira Costa, Roberto César Pereira Lima-Júnior, Karoline Sabóia Aragão, Raul Pinheiro Medeiros, Raphael Dias Marques-Neto, Lucas de Sá Grassi, Leandro Linhares Leite, Lorena Guimaraes Nunes, José Wilson Benevides de Mesquita Neto, Gerly Anne de Castro Brito, Marcellus Henrique Loiola Pontes de Souza, Paulo Roberto Carvalho de Almeida, Ronaldo Albuquerque Ribeiro
First-line gefitinib therapy for elderly patients with non-small cell lung cancer harboring EGFR mutation: Central Japan Lung Study Group 0901
Kosuke Takahashi, Hiroshi Saito, Yoshinori Hasegawa, Masahiko Ando, Masashi Yamamoto, Eiji Kojima, Yasuteru Sugino, Tomoki Kimura, Fumio Nomura, Tomohiko Ogasawara, Joe Shindoh, Norio Yoshida, Ryujiro Suzuki
Impact of cytochrome P450 3A4 inducer and inhibitor on the pharmacokinetics of trabectedin in patients with advanced malignancies: open-label, multicenter studies
Jean-Pascal Machiels, Arthur Staddon, Catherine Herremans, Chi Keung, Apexa Bernard, Charles Phelps, Nushmia Z. Khokhar, Roland Knoblauch, Trilok V. Parekh, Luc Dirix, Sunil Sharma
Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma
Robert J. Motzer, Thomas E. Hutson, Gary R. Hudes, Robert A. Figlin, Jean-Francois Martini, Patricia A. English, Xin Huang, Olga Valota, J. Andrew Williams
Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study
Zuleyha Akgun, Sezer Saglam, Serap Yucel, Zeynep Gural, Emre Balik, Gokhan Cipe, Seyma Yildiz, Sadettin Kilickap, Alper Okyar, Esra Kaytan-Saglam
Pretherapeutic uracil and dihydrouracil levels in saliva of colorectal cancer patients are associated with toxicity during adjuvant 5-fluorouracil-based chemotherapy
Göran Carlsson, Elisabeth Odin, Bengt Gustavsson, Yvonne Wettergren
A pharmacodynamic model of Bcr–Abl signalling in chronic myeloid leukaemia
Robert C. Jackson, Tomas Radivoyevitch
Predictive value of APE1, BRCA1, ERCC1 and TUBB3 expression in patients with advanced non-small cell lung cancer (NSCLC) receiving first-line platinum–paclitaxel chemotherapy
Zheng Li, Yi Qing, Wei Guan, Mengxia Li, Yu Peng, Shiheng Zhang, Yanli Xiong, Dong Wang
Anticancer activity of VDR-coregulator inhibitor PS121912
Preetpal S. Sidhu, Kelly Teske, Belaynesh Feleke, Nina Y. Yuan, Margaret L. Guthrie, Grant B. Fernstrum, Nishita D. Vyas, Lanlan Han, Joshua Preston, Jonathan W. Bogart, Nicholas R. Silvaggi, James M. Cook, Rakesh K. Singh, Daniel D. Bikle, Leggy A. Arnold
Phase II gemcitabine and capecitabine combination therapy in recurrent or metastatic breast cancer patients pretreated with anthracycline and taxane
Ji Soo Park, Hei-Cheul Jeung, Sun Young Rha, Joong Bae Ahn, Beodeul Kang, Hong Jae Chon, Min Hee Hong, Seungtaek Lim, Woo Ick Yang, Chung Mo Nam, Hyun Cheol Chung
Resistance to the antiproliferative effect induced by a short-chain ceramide is associated with an increase of glucosylceramide synthase, P-glycoprotein, and multidrug-resistance gene-1 in cervical cancer cells
Gisela Gutiérrez-Iglesias, Yamilec Hurtado, Icela Palma-Lara, Rebeca López-Marure
Population pharmacokinetic and covariate analysis of pertuzumab, a HER2-targeted monoclonal antibody, and evaluation of a fixed, non-weight-based dose in patients with a variety of solid tumors
Amit Garg, Angelica Quartino, Jing Li, Jin Jin, D. Russell Wada, Hanbin Li, Javier Cortés, Virginia McNally, Graham Ross, Jennifer Visich, Bert Lum
Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children’s Oncology Group
Patrick Thompson, Heather E. Wheeler, Shannon M. Delaney, Rachel Lorier, Ulrich Broeckel, Meenakshi Devidas, Gregory H. Reaman, Kathleen Scorsone, Lillian Sung, M. Eileen Dolan, Stacey L. Berg
A prospective study of biomarker-guided chemotherapy in patients with non-small cell lung cancer
Qiang Zhang, Xiaoli Zhu, Li Zhang, Siqing Sun, Jing Huang, Yong Lin
The combination of Cl-IB-MECA with paclitaxel: a new anti-metastatic therapeutic strategy for melanoma
Ana S. Soares, Vera M. Costa, Carmen Diniz, Paula Fresco
A pilot study of S-1-based concurrent chemoradiotherapy in patients with biliary tract cancer
Hee Man Kim, Kyong Joo Lee, Jihye Cha, Moon Jae Chung, Seungmin Bang, Jinsil Seong, Si Young Song, Seung Woo Park
The effect of formulation and food consumption on the bioavailability of dovitinib (TKI258) in patients with advanced solid tumors
Sunil Sharma, Carolyn D. Britten, Joanne Mortimer, Swarupa Kulkarni, Michelle Quinlan, Angela Liu, Jeffrey W. Scott, Daniel George
Acetyl-l-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network
Natalie Callander, Stephanie Markovina, Jens Eickhoff, Paul Hutson, Toby Campbell, Peiman Hematti, Ronald Go, Robert Hegeman, Walter Longo, Eliot Williams, Fotis Asimakopoulos, Shigeki Miyamoto