Ausgabe 5/2005
Inhalt (15 Artikel)
Enhanced antitumor activity of irofulven in combination with irinotecan in pediatric solid tumor xenograft models
Michael H. Woo, Jennifer K. Peterson, Catherine Billups, Hua Liang, Mary-Ann Bjornsti, Peter J. Houghton
Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2
Tatsuya Itoh, Shirou Itagaki, Yoshinobu Sumi, Takeshi Hirano, Isao Takemoto, Ken Iseki
Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis
Mohammad H. Pourgholami, Javed Akhter, Lisa Wang, Ying Lu, David L. Morris
Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC
Mark N. Kirstein, John C. Panetta, Amar Gajjar, Geeta Nair, Lisa C. Iacono, Burgess B. Freeman III, Clinton F. Stewart
In vivo antitumor activity by 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone in a solid human carcinoma xenograft model
Chun-Lin Ye, Jian-Wen Liu, Dong-Zhi Wei, Yan-Hua Lu, Feng Qian
A phase I, dose-finding study of irinotecan (CPT-11) short i.v. infusion combined with fixed dose of 5-fluorouracil (5-FU) protracted i.v. infusion in adult patients with advanced solid tumours
Javier Sastre, Luis Paz-Ares, Antonio Carcas, Rosario Alfonso, Cristina Grávalos, Jesus Frías, Pedro Guerra, Linda Pronk, Hernán Cortés-Funes, Eduardo Díaz-Rubio
EM012, a microtubule-interfering agent, inhibits the progression of multidrug-resistant human ovarian cancer both in cultured cells and in athymic nude mice
Jun Zhou, Min Liu, Roopa Luthra, Jeremy Jones, Ritu Aneja, Ramesh Chandra, Rajeshwar R. Tekmal, Harish C. Joshi
Phase I trial of weekly docetaxel with a 4-weekly cisplatin administration in patients with advanced gastric carcinoma
Aristides Polyzos, Konstantinos Syrigos, John Stergiou, Christos Panopoulos, Anna Potamianou, Lambros Vamvakas, Vassilios Georgoulias
Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen
Young Chai Lim, Zeruesenay Desta, David A. Flockhart, Todd C. Skaar
Effects of docetaxel on antigen presentation-related functions of human monocyte-derived dendritic cells
Hiroshi Nakashima, Akira Tasaki, Makoto Kubo, Hideo Kuroki, Kotaro Matsumoto, Masao Tanaka, Masafumi Nakamura, Takashi Morisaki, Mitsuo Katano
Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma
M. Joerger, A. D. R. Huitema, P. L. Meenhorst, J. H. M. Schellens, J. H. Beijnen
Phase I study of the novel taxane CT-2103 in patients with advanced solid tumors
Maria Luisa Veronese, Keith Flaherty, Amy Kramer, Barbara A. Konkle, Mark Morgan, James P. Stevenson, Peter J. O’Dwyer
Secretory transport of irinotecan metabolite SN-38 across isolated intestinal tissue
Shirou Itagaki, Yoshinobu Sumi, Soji Shimamoto, Tatsuya Itoh, Takeshi Hirano, Isao Takemoto, Ken Iseki
Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin
Milly E. de Jonge, Alwin D. R. Huitema, Selma M. van Dam, Jos H. Beijnen, Sjoerd Rodenhuis