Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 1/2012

01.01.2012 | Reproductive Medicine

Cervical gland area: a new sonographic marker in predicting preterm delivery

verfasst von: Nargess Afzali, Marzieh Mohajeri, Abdolreza Malek, Atefeh Alamatian

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 1/2012

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Preterm delivery is one of the important causes of morbidity and mortality in newborns. Nowadays, a new sonographic marker is suggested for prediction of preterm delivery which is termed “Cervical Gland Area” (CGA). Absence of normal mucosal glands of the cervix can be utilized as a predictor in preterm delivery. This study was performed to evaluate the role of absence of CGA for the prediction of preterm delivery <37 weeks.

Methods

Trans-vaginal ultrasonography was performed on 600 pregnant women at 16–19 weeks of gestational age. Cervical gland area and cervical length were evaluated. Women with cervical length <25 mm were conducted to cerclage and excluded from the study. Age, number of pregnancies and history of previous preterm deliveries were recorded in questionnaires. The date of delivery was recorded. Statistical analysis was performed by version 18 SPSS and P value <0.05 was significant.

Results

Spontaneous preterm delivery was seen in 6.7% of all women. There was no significant difference in age, cervical length, the number of pregnancies and history of previous preterm deliveries between term pregnancies and preterm cases. CGA was detected in 77.1% of term pregnancies comparing with 55% in preterm group; which was significantly different (P value = 0.002).

Conclusions

Non detection of CGA at second trimester ultrasonography is a predictor of preterm delivery.
Literatur
1.
Zurück zum Zitat Canry C, Gibbs RS (2008) Preterm labor and postterm delivery. In: Gibbs RS (ed) Danforths obstetrics and gynecology. Lippincott Williams and Wilkins, Philadelphia, pp 165–186 Canry C, Gibbs RS (2008) Preterm labor and postterm delivery. In: Gibbs RS (ed) Danforths obstetrics and gynecology. Lippincott Williams and Wilkins, Philadelphia, pp 165–186
2.
Zurück zum Zitat Hassan SA, Romero R, Berry SM, Dang K, Blackwell SC, Treawell MC, Wolfe HM (2000) Patients with an ultrsonographic cervical length <15 mm have nearly a 50% risk of early spontaneous preterm delivery. Am J Obstet Gynecol 182:1458–1467PubMedCrossRef Hassan SA, Romero R, Berry SM, Dang K, Blackwell SC, Treawell MC, Wolfe HM (2000) Patients with an ultrsonographic cervical length <15 mm have nearly a 50% risk of early spontaneous preterm delivery. Am J Obstet Gynecol 182:1458–1467PubMedCrossRef
3.
Zurück zum Zitat Iams JD, Goldenberg RL, Meis PJ, Mercer BM, Moawal A, Das A, Thom E, McNellis D, Copper RL, Johnson F, Roberts JM (1996) The length of the cervix and the risk of spontaneous premature delivery, National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network. N Eng J Med 334:567–572CrossRef Iams JD, Goldenberg RL, Meis PJ, Mercer BM, Moawal A, Das A, Thom E, McNellis D, Copper RL, Johnson F, Roberts JM (1996) The length of the cervix and the risk of spontaneous premature delivery, National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network. N Eng J Med 334:567–572CrossRef
4.
Zurück zum Zitat Varma TR, Patel RH, Pillai U (1986) Ultrasound assessment of the cervix in “at risk” patients. Acta Obstet Gynecol Scand 65:147–152PubMedCrossRef Varma TR, Patel RH, Pillai U (1986) Ultrasound assessment of the cervix in “at risk” patients. Acta Obstet Gynecol Scand 65:147–152PubMedCrossRef
5.
Zurück zum Zitat Podonik K, Bulic M, Smiljanic N, Bistricki J (1988) Ultrasonography in the detection of cervical incompetency. J Clin Ultrasound 13:383–391CrossRef Podonik K, Bulic M, Smiljanic N, Bistricki J (1988) Ultrasonography in the detection of cervical incompetency. J Clin Ultrasound 13:383–391CrossRef
6.
Zurück zum Zitat Owen J, Yost N, Berghella V (2001) Mid-trimester endovaginal sonography in women at high risk for spontaneous preterm birth. JAMA 286:1340–1350PubMedCrossRef Owen J, Yost N, Berghella V (2001) Mid-trimester endovaginal sonography in women at high risk for spontaneous preterm birth. JAMA 286:1340–1350PubMedCrossRef
7.
Zurück zum Zitat Sekiya T, Ishihara K, Yoshimatsu K (1998) Detection rate of the cervical gland area during pregnancy by transvaginal sonography in the assessment of cervical maturation. Ultrasound Obstet Gynecol 12:328–333PubMedCrossRef Sekiya T, Ishihara K, Yoshimatsu K (1998) Detection rate of the cervical gland area during pregnancy by transvaginal sonography in the assessment of cervical maturation. Ultrasound Obstet Gynecol 12:328–333PubMedCrossRef
8.
Zurück zum Zitat Fukami T, Ishihara K, Sekiya T, Araki T (2003) Is transvaginal ultrasonography at mid-trimester useful for predicting early spontaneous preterm birth? J Nippon Med Sch 70:135–140CrossRef Fukami T, Ishihara K, Sekiya T, Araki T (2003) Is transvaginal ultrasonography at mid-trimester useful for predicting early spontaneous preterm birth? J Nippon Med Sch 70:135–140CrossRef
9.
Zurück zum Zitat Guzman ER, Walters C, Ananth CV, O’Reilly-green C, Benito CW, Palermo A, Vintzileos AM (2001) A comparison of sonographic cervical parameters in predicting spontaneous preterm birth in high-risk singleton gestation. Ultrasound Obstet Gynecol 18:204–210PubMedCrossRef Guzman ER, Walters C, Ananth CV, O’Reilly-green C, Benito CW, Palermo A, Vintzileos AM (2001) A comparison of sonographic cervical parameters in predicting spontaneous preterm birth in high-risk singleton gestation. Ultrasound Obstet Gynecol 18:204–210PubMedCrossRef
10.
Zurück zum Zitat Moron AF, Mattor R, Diniz ALD, Andrade SGA, Bussamra LCS (2006) Cervical gland area as an ultrasonographic marker for preterm delivery. International Journal of Gynecology and Obstetrics 93:214–219PubMedCrossRef Moron AF, Mattor R, Diniz ALD, Andrade SGA, Bussamra LCS (2006) Cervical gland area as an ultrasonographic marker for preterm delivery. International Journal of Gynecology and Obstetrics 93:214–219PubMedCrossRef
11.
Zurück zum Zitat Grgic O, Matijevic R, Vasilj O (2005) Qualitative glandular cervical score as potential new sonomorphological parameter in screening for preterm delivery. Am J obstet and Gynecol 32:333–338CrossRef Grgic O, Matijevic R, Vasilj O (2005) Qualitative glandular cervical score as potential new sonomorphological parameter in screening for preterm delivery. Am J obstet and Gynecol 32:333–338CrossRef
12.
Zurück zum Zitat Asakura H, Fukami T, Kurashina R, Tateyama N, Doi D, Takeshita T (2009) Significance of cervical gland area in predicting preterm birth for patients with threatened preterm delivery: comparison with cervical length and fetal fibronectin. Gynecol Obstet Invest 68:1–8PubMedCrossRef Asakura H, Fukami T, Kurashina R, Tateyama N, Doi D, Takeshita T (2009) Significance of cervical gland area in predicting preterm birth for patients with threatened preterm delivery: comparison with cervical length and fetal fibronectin. Gynecol Obstet Invest 68:1–8PubMedCrossRef
13.
Zurück zum Zitat Topkins P (1949) Histologic appearance of endocervix during menstrual cycle. Am J Obstet Gynecol 58:654–663PubMed Topkins P (1949) Histologic appearance of endocervix during menstrual cycle. Am J Obstet Gynecol 58:654–663PubMed
14.
Zurück zum Zitat Fluhmann CF, Dickmann Z (1958) The basic pattern of the glandular structures of the cervix uteri. Obstet Gynecol 11:543–555PubMed Fluhmann CF, Dickmann Z (1958) The basic pattern of the glandular structures of the cervix uteri. Obstet Gynecol 11:543–555PubMed
15.
Zurück zum Zitat Yoshimatsu K, Sekiya T, Ishihara K, Fukami T, Otabe T, Araki T (2002) Detection of the cervical gland area in threatened preterm labor using transvaginal sonography in the assessment of cervical maturation and the outcome of pregnancy. Gynecol Obstet Invest 53:149–156PubMedCrossRef Yoshimatsu K, Sekiya T, Ishihara K, Fukami T, Otabe T, Araki T (2002) Detection of the cervical gland area in threatened preterm labor using transvaginal sonography in the assessment of cervical maturation and the outcome of pregnancy. Gynecol Obstet Invest 53:149–156PubMedCrossRef
Metadaten
Titel
Cervical gland area: a new sonographic marker in predicting preterm delivery
verfasst von
Nargess Afzali
Marzieh Mohajeri
Abdolreza Malek
Atefeh Alamatian
Publikationsdatum
01.01.2012
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 1/2012
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-011-1986-7

Weitere Artikel der Ausgabe 1/2012

Archives of Gynecology and Obstetrics 1/2012 Zur Ausgabe

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

26.04.2024 Hirsutismus Nachrichten

Laser- und Lichtbehandlungen können bei Frauen mit polyzystischem Ovarialsyndrom (PCOS) den übermäßigen Haarwuchs verringern und das Wohlbefinden verbessern – bei alleiniger Anwendung oder in Kombination mit Medikamenten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bislang gibt es kein Medikament zur Prävention von Wochenbettdepressionen. Das Injektionsanästhetikum Esketamin könnte womöglich diese Lücke füllen.

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

22.04.2024 DGIM 2024 Kongressbericht

Durch die Häufung nach der COVID-19-Pandemie sind Infektionen mit dem Respiratorischen Synzytial-Virus (RSV) in den Fokus gerückt. Fachgesellschaften empfehlen eine Impfung inzwischen nicht nur für Säuglinge und Kleinkinder.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.