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Graefe's Archive for Clinical and Experimental Ophthalmology

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14.10.2017 | Retinal Disorders

Choriocapillaris layer imaging with swept-source optical coherence tomography angiography in lamellar and full-thickness macular hole

verfasst von: Jaemoon Ahn, Gyeongmin Yoo, Jee Taek Kim, Seong-Woo Kim, Jaeryung Oh

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 1/2018

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Abstract

Purpose

To present characteristics of choriocapillaris layer imaging with swept-source optical coherence tomography angiography (SS-OCTA) in eyes with macular hole (MH).

Methods

Patients with MH were included. Vascular density of choriocapillaris (VDC) and central flow void areas were obtained using SS-OCTA. Data were compared with age- and gender-matched normal controls.

Results

Fifty-one patients with MH and 51 controls were included. Among the 51 patients with MH, 19 had lamellar MH (LMH) and 32 had full-thickness MH (FTMH). While VDC in LMH (79.26 ± 4.06%) was not significantly different from that seen in fellow eyes (79.88 ± 4.28%, P = 0.729) and normal controls (80.53 ± 4.21%, P = 1.000), VDC in surgically closed FTMH (74.60 ± 7.37%) was similar to that of fellow eyes (75.45 ± 7.39%, P = 0.400) but lower than that of controls (78.37 ± 7.13%, P = 0.011). On univariate analysis of 32 patients with unilateral sealed FTMH, VDC was not correlated with basal hole area (P = 0.797) or preoperative area of disrupted ellipsoid zone (P = 0.863). Central flow void was detected in 32 eyes. Mean central flow void area was 0.82 ± 0.84 mm², which correlated with preoperative area of disrupted ellipsoid zone (P = 0.001).

Conclusions

Choriocapillaris layer imaging using SS-OCTA showed that choriocapillaris in both eyes of patients with unilateral FTMH had different characteristics from eyes with LMH or normal controls. These results suggest that variation in choriocapillaris layer flow is involved in the pathogenesis of MH.

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Titel: Choriocapillaris layer imaging with swept-source optical coherence tomography angiography in lamellar and full-thickness macular hole
verfasst von: Jaemoon Ahn
Gyeongmin Yoo
Jee Taek Kim
Seong-Woo Kim
Jaeryung Oh
Publikationsdatum: 14.10.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 1/2018
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-017-3814-7

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Choriocapillaris layer imaging with swept-source optical coherence tomography angiography in lamellar and full-thickness macular hole

Abstract

Purpose

Methods

Results

Conclusions

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