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Pediatric Nephrology
Erschienen in: Pediatric Nephrology 6/2011

01.06.2011 | Review

Clinical and Molecular Insights into Tuberous Sclerosis Complex Renal Disease

verfasst von: Brian J. Siroky, Hong Yin, John J. Bissler

Erschienen in: Pediatric Nephrology | Ausgabe 6/2011

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Abstract

Patients with tuberous sclerosis complex are at great risk of developing renal lesions as part of their disease. These lesions include renal cysts and tumors. Significant advances in understanding the cell biology of these renal lesions has already led to clinical trials demonstrating that pharmacological interventions are likely possible. This review focuses on the pathology of these renal lesions, their underlying cell biology, and the possible therapeutic strategies that may prove to significantly improve care for these patients.
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Metadaten
Titel
Clinical and Molecular Insights into Tuberous Sclerosis Complex Renal Disease
verfasst von
Brian J. Siroky
Hong Yin
John J. Bissler
Publikationsdatum
01.06.2011
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Nephrology / Ausgabe 6/2011
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-010-1689-5

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Pediatric Nephrology 6/2011 Zur Ausgabe

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Results of medical treatment and metabolic risk factors in children with urolithiasis

Letter to the Editors

Pauci-immune crescentic glomerulonephritis complicating Sjögren's syndrome in a 12-year-old girl

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Growth of kidney-transplanted pediatric patients treated with sirolimus

Letter to the Editors

Children with chronic kidney disease: are they insured as adults?

Review

Uraemic vasculopathy in children with chronic kidney disease: prevention or damage limitation?

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Primary antiphospholipid syndrome presenting as renal vein thrombosis and membranous nephropathy

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