Skip to main content
Erschienen in: European Archives of Oto-Rhino-Laryngology 10/2016

04.04.2016 | Rhinology

Clinical and morphological aspects of adenocarcinomas of the intestinal type in the inner nose: a retrospective multicenter analysis

verfasst von: K. Donhuijsen, I. Kollecker, P. Petersen, N. Gaßler, J. Wolf, H.-G. Schroeder

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 10/2016

Einloggen, um Zugang zu erhalten

Abstract

Clinical and histological parameters from 117 patients with wood dust-related sinonasal adenocarcinomas of intestinal type (ITAC) were analyzed and correlated with a follow-up period of 5 years at least. The rate of survival for 5 years was 53.1 % and for 10 years 30.2 %. Only 33 patients were free of disease. 74.2 % of patients with recurrences died in relation to ITAC. As expected, tumors of T4-category had the worst prognosis. The mucus content of a tumor was the most important histological parameter. Endonasal methods of surgery had no more positive survival rates after 5 years. An effect of radiotherapy has to be in discussion. The high incidence of tumor recurrences requires control examinations consistently.
Literatur
1.
Zurück zum Zitat Franchi A, Santucci M, Wenig BM; Tumours oft he nasal cavity and paranasal sinuses; Adenocarcinoma, Intestinal-type adenocarcinomas; World Health Organization Classification of Tumours (2005) Pathology and Genetics of Head and Neck Tumours, Lyon, pp 20–22 Franchi A, Santucci M, Wenig BM; Tumours oft he nasal cavity and paranasal sinuses; Adenocarcinoma, Intestinal-type adenocarcinomas; World Health Organization Classification of Tumours (2005) Pathology and Genetics of Head and Neck Tumours, Lyon, pp 20–22
2.
Zurück zum Zitat Böör A, Jurkovic I, Dudríková K, Kavecanský V, Friedmann I (1996) Pathology in focus intestinal-type sinonasal adenocarcinoma: a sporadic case. J Laryngol Otol 110:805–810CrossRefPubMed Böör A, Jurkovic I, Dudríková K, Kavecanský V, Friedmann I (1996) Pathology in focus intestinal-type sinonasal adenocarcinoma: a sporadic case. J Laryngol Otol 110:805–810CrossRefPubMed
3.
Zurück zum Zitat Whiteside OJH, Corbridge RJ, Capper JWR (2010) Esme Hadfield (1921-92) and the Wycombe woodworkers. J Med Biogr 18:24–26CrossRefPubMed Whiteside OJH, Corbridge RJ, Capper JWR (2010) Esme Hadfield (1921-92) and the Wycombe woodworkers. J Med Biogr 18:24–26CrossRefPubMed
5.
Zurück zum Zitat Sobin LH, Gospodarowicz MK, Wittekind C (2009) TNM Classification of Malignant Tumours, 7th edn. Willy-Blackwell, Weinheim, pp 43–47 Sobin LH, Gospodarowicz MK, Wittekind C (2009) TNM Classification of Malignant Tumours, 7th edn. Willy-Blackwell, Weinheim, pp 43–47
6.
Zurück zum Zitat Kleinsasser O, Schroeder HG (1988) Adenocarcinomas of the inner nose after exposure to wood dust. Arch Otorhinolaryngol 245:1–15CrossRefPubMed Kleinsasser O, Schroeder HG (1988) Adenocarcinomas of the inner nose after exposure to wood dust. Arch Otorhinolaryngol 245:1–15CrossRefPubMed
7.
Zurück zum Zitat Donhuijsen K, Hattenberger S, Schroeder HG (2004) Sinunasale Carcinome nach Holzstaubbelastung. Der Pathologe 25(1):14–20CrossRefPubMed Donhuijsen K, Hattenberger S, Schroeder HG (2004) Sinunasale Carcinome nach Holzstaubbelastung. Der Pathologe 25(1):14–20CrossRefPubMed
8.
Zurück zum Zitat Mayr SI, Hafizovic K, Waldfahrer F, Iro H, Kütting B (2010) Characterization of initial clinical symptoms and risk factors for sinonasal adenocarcinomas: results of a case-control study. Int Arch Occup Environ Health 83(6):631–638CrossRefPubMed Mayr SI, Hafizovic K, Waldfahrer F, Iro H, Kütting B (2010) Characterization of initial clinical symptoms and risk factors for sinonasal adenocarcinomas: results of a case-control study. Int Arch Occup Environ Health 83(6):631–638CrossRefPubMed
9.
Zurück zum Zitat Orvcidas LJ, Lewis JE, Weaver AL, Bagniewski SM, Olsen KD (2005) Adenocarcinoma of the nose and paranasal sinuses: a retrospective study of diagnosis, histologic characteristics, and outcomes in 24 patients. Head Neck 27(5):370–375CrossRef Orvcidas LJ, Lewis JE, Weaver AL, Bagniewski SM, Olsen KD (2005) Adenocarcinoma of the nose and paranasal sinuses: a retrospective study of diagnosis, histologic characteristics, and outcomes in 24 patients. Head Neck 27(5):370–375CrossRef
10.
Zurück zum Zitat Franchi A, Gallo O, Santucci M (1999) Clinical relevance of the histological classification of sinonasal intestinal-type adenocarcinomas. Hum Pathol 30(10):1140–1145CrossRefPubMed Franchi A, Gallo O, Santucci M (1999) Clinical relevance of the histological classification of sinonasal intestinal-type adenocarcinomas. Hum Pathol 30(10):1140–1145CrossRefPubMed
11.
Zurück zum Zitat Tilson MP, Gallia GL, Bishop JA (2014) Among sinonasal tumors, CDX-2 immunoexpression is not restricted to intestinal-type adenocarcinomas. Head Neck Pathol 8:59–65CrossRefPubMed Tilson MP, Gallia GL, Bishop JA (2014) Among sinonasal tumors, CDX-2 immunoexpression is not restricted to intestinal-type adenocarcinomas. Head Neck Pathol 8:59–65CrossRefPubMed
12.
Zurück zum Zitat Kennedy MT, Jordan RCK, Berean KW (2004) Perez-Ordoñez; Expression pattern of CK7, CK20, CDX-2, and villin in intestinal-type sinonasal adenocarcinoma. J Clin Pathol 57:932–937CrossRefPubMedPubMedCentral Kennedy MT, Jordan RCK, Berean KW (2004) Perez-Ordoñez; Expression pattern of CK7, CK20, CDX-2, and villin in intestinal-type sinonasal adenocarcinoma. J Clin Pathol 57:932–937CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Lee JT, Garg R, Brunworth J, Keschner D, Thompson LDR (2013) Sinonasal respiratory epithelial adenomatoid hamartomas: Series of 51 cases and literature review. Am J Rhinol Allergy 27:322–328CrossRefPubMed Lee JT, Garg R, Brunworth J, Keschner D, Thompson LDR (2013) Sinonasal respiratory epithelial adenomatoid hamartomas: Series of 51 cases and literature review. Am J Rhinol Allergy 27:322–328CrossRefPubMed
14.
Zurück zum Zitat Llorente JL, Nuñez F, Rodrigo JP, Fernández León R, Alvarez C, Hermsen M, Suárez C (2008) Sinonasal adenocarcinomas: our experience. Acta Otorrinolaringol Esp 59:235–238CrossRefPubMed Llorente JL, Nuñez F, Rodrigo JP, Fernández León R, Alvarez C, Hermsen M, Suárez C (2008) Sinonasal adenocarcinomas: our experience. Acta Otorrinolaringol Esp 59:235–238CrossRefPubMed
15.
Zurück zum Zitat Tripodi D, Ferron C, Malard O, de Montreuil CB, Planche L, Sebille-Rivain V, Roedlich C, Quéméner S, Renaudin K, Longuenesse C, Verger C, Meflah K, Gratas C, Géraut C (2011) Relevance of both individual risk factors and occupational exposure in cancer survival studies: the example of intestinal type sinonasal adenocarcinoma. Laryngoscope 121(9):2011–2018PubMed Tripodi D, Ferron C, Malard O, de Montreuil CB, Planche L, Sebille-Rivain V, Roedlich C, Quéméner S, Renaudin K, Longuenesse C, Verger C, Meflah K, Gratas C, Géraut C (2011) Relevance of both individual risk factors and occupational exposure in cancer survival studies: the example of intestinal type sinonasal adenocarcinoma. Laryngoscope 121(9):2011–2018PubMed
16.
Zurück zum Zitat Bernardo T, Ferreira E, Silva CJ, Monteiro E (2013) Sinonasal adenocarcinoma—experience of an oncology center. Int J Otol Head Neck Surg 2:13–16 Bernardo T, Ferreira E, Silva CJ, Monteiro E (2013) Sinonasal adenocarcinoma—experience of an oncology center. Int J Otol Head Neck Surg 2:13–16
17.
Zurück zum Zitat El Ayoubi A, Poizat F, Garrel R, Costes V, Guerrier B, Essakalli L, Kzadri M, Crampette L (2009) Sinonasal adenocarcinomas reviewed. Prognostic value of WHO 2005 histological classification. Ann Otol Chir Cervicofac 126(4):175–181CrossRef El Ayoubi A, Poizat F, Garrel R, Costes V, Guerrier B, Essakalli L, Kzadri M, Crampette L (2009) Sinonasal adenocarcinomas reviewed. Prognostic value of WHO 2005 histological classification. Ann Otol Chir Cervicofac 126(4):175–181CrossRef
18.
Zurück zum Zitat Veloso-Teles R, Ribeiro I, Castro-Silva J, Monteiro E (2015) Adenocarcinomas oft he sinonasal tract: a case series from an Oncology Centre in Northern Portugal. Eur Arch Otorhinolaryngol 272(8):1913–1921CrossRefPubMed Veloso-Teles R, Ribeiro I, Castro-Silva J, Monteiro E (2015) Adenocarcinomas oft he sinonasal tract: a case series from an Oncology Centre in Northern Portugal. Eur Arch Otorhinolaryngol 272(8):1913–1921CrossRefPubMed
19.
Zurück zum Zitat Donhuijsen K, Kollecker I, Petersen P, Gaßler N, Schulze J, Schroeder HG (2016) Metastatic behavior of sinonasal adenocarcinoma oft he intestinal type (ITAC). Eur Arch Otorhinolaryngol 273:649–654CrossRefPubMed Donhuijsen K, Kollecker I, Petersen P, Gaßler N, Schulze J, Schroeder HG (2016) Metastatic behavior of sinonasal adenocarcinoma oft he intestinal type (ITAC). Eur Arch Otorhinolaryngol 273:649–654CrossRefPubMed
20.
Zurück zum Zitat Franquemont DW, Fechner RE, Mills SE (1991) Histologic classification of sinonasal intestinal-type adenocarcinoma. Am Surg Pathol 15:275–368 Franquemont DW, Fechner RE, Mills SE (1991) Histologic classification of sinonasal intestinal-type adenocarcinoma. Am Surg Pathol 15:275–368
21.
Zurück zum Zitat Franchi A, Palomba A, Fondi C, Miligi L, Paglierani M, Pepi M, Santucci M (2011) Immunohistochemical investigation of tumorigenic pathways in sinonasal intestinal-type adenocarcinoma. A tissue microarray analyses of 62 cases. Histopathology 59(1):98–105CrossRefPubMed Franchi A, Palomba A, Fondi C, Miligi L, Paglierani M, Pepi M, Santucci M (2011) Immunohistochemical investigation of tumorigenic pathways in sinonasal intestinal-type adenocarcinoma. A tissue microarray analyses of 62 cases. Histopathology 59(1):98–105CrossRefPubMed
22.
Zurück zum Zitat Nitsche U, Zimmermann A, Späth C, Müller T, Maak M, Schuster T, Slotta-Huspenina J, Käser SA, Michalski CW, Janssen KP, Friess H, Rosenberg R, Bader FG (2013) Mucinous and signet-ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis. Am Surg 258(5):775–782 Nitsche U, Zimmermann A, Späth C, Müller T, Maak M, Schuster T, Slotta-Huspenina J, Käser SA, Michalski CW, Janssen KP, Friess H, Rosenberg R, Bader FG (2013) Mucinous and signet-ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis. Am Surg 258(5):775–782
23.
Zurück zum Zitat Langner C, Harbaum L, Pollheimer MJ, Kornprat P, Lindtner RA, Schlemmer A, Vieth M, Rehak P (2012) Mucinous differentiation in colorectal cancer—indicator of poor prognosis? Histopathology 60:1060–1072CrossRefPubMed Langner C, Harbaum L, Pollheimer MJ, Kornprat P, Lindtner RA, Schlemmer A, Vieth M, Rehak P (2012) Mucinous differentiation in colorectal cancer—indicator of poor prognosis? Histopathology 60:1060–1072CrossRefPubMed
24.
Zurück zum Zitat Claus F, Boterberg T, Ost P et al (2002) Postoperative radiotherapy for adenocarcinoma of the ethmoid sinuses: treatment results for 47 patients. Int J Radiat Oncol Biol Phys 54:1089–1094CrossRefPubMed Claus F, Boterberg T, Ost P et al (2002) Postoperative radiotherapy for adenocarcinoma of the ethmoid sinuses: treatment results for 47 patients. Int J Radiat Oncol Biol Phys 54:1089–1094CrossRefPubMed
25.
Zurück zum Zitat Lund VJ, Chrisholm EJ, Takes RP et al (2012) Evidence for treatment strategies in sinonasal adenocarcinoma. Head Neck 34:1168–1178CrossRefPubMed Lund VJ, Chrisholm EJ, Takes RP et al (2012) Evidence for treatment strategies in sinonasal adenocarcinoma. Head Neck 34:1168–1178CrossRefPubMed
26.
Zurück zum Zitat Resto VA, Krane JF, Faquin WC, Lin DT (2006) Immunohistochemical distinction of intestinal-type sinonasal adenocarcinoma from metastatic adenocarcinoma of intestinal origin. Ann Otol Rhinol Laryngol 115(1):59–64CrossRefPubMed Resto VA, Krane JF, Faquin WC, Lin DT (2006) Immunohistochemical distinction of intestinal-type sinonasal adenocarcinoma from metastatic adenocarcinoma of intestinal origin. Ann Otol Rhinol Laryngol 115(1):59–64CrossRefPubMed
27.
Zurück zum Zitat Hanna E, DeMonte F, Ibrahim S et al (2009) Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg 135:1219–1224CrossRefPubMed Hanna E, DeMonte F, Ibrahim S et al (2009) Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg 135:1219–1224CrossRefPubMed
28.
Zurück zum Zitat Bhayani MK, Yilmaz T, Sweeney A, Calzada G, Roberts DB, Levine NB, DeMonte F, Hanna EY, Kupferman ME (2014) Sinonasal adenocarcinoma: a 16-year experience at a single institution. Head Neck 36:1490–1496PubMed Bhayani MK, Yilmaz T, Sweeney A, Calzada G, Roberts DB, Levine NB, DeMonte F, Hanna EY, Kupferman ME (2014) Sinonasal adenocarcinoma: a 16-year experience at a single institution. Head Neck 36:1490–1496PubMed
29.
Zurück zum Zitat Knegt PP, Ah-See KW, vd Velden LA, Kerrebijn J (2001) Adenocarcinoma oft he ethmoidal sinus complex: surgical debulking and topical fluorouracil may be the optimal treatment. Arch Otolaryngol Head Neck Surg 127(4):141–146CrossRefPubMed Knegt PP, Ah-See KW, vd Velden LA, Kerrebijn J (2001) Adenocarcinoma oft he ethmoidal sinus complex: surgical debulking and topical fluorouracil may be the optimal treatment. Arch Otolaryngol Head Neck Surg 127(4):141–146CrossRefPubMed
30.
Zurück zum Zitat Almeyda R, Capper J (2008) Is surgical debridement and topical 5 fluorouracil the optimum treatment for woodworkers’ adenocarcinoma oft he ethmoid sinuses? A case-controlled study of a 20-year experience. Clin Otolaryngol 33(5):435–441CrossRefPubMed Almeyda R, Capper J (2008) Is surgical debridement and topical 5 fluorouracil the optimum treatment for woodworkers’ adenocarcinoma oft he ethmoid sinuses? A case-controlled study of a 20-year experience. Clin Otolaryngol 33(5):435–441CrossRefPubMed
31.
Zurück zum Zitat Chiu AG, Vijay R, Ramakrishnan VR, Suh JO (2001) Sinonasal tumors. Jaypee Brothers, Verlag, pp 120 ff Chiu AG, Vijay R, Ramakrishnan VR, Suh JO (2001) Sinonasal tumors. Jaypee Brothers, Verlag, pp 120 ff
32.
Zurück zum Zitat Shah JP, Patel SG, Singh B (2012) Head and neck surgery and oncology. Elsevier Health Sciences, pp 113 Shah JP, Patel SG, Singh B (2012) Head and neck surgery and oncology. Elsevier Health Sciences, pp 113
33.
Zurück zum Zitat Lund VJ, Howard DJ, Wei WI (2014) Tumors oft he nose, sinuses, and nasopharynx. Thieme, Stuttgart, pp 137–150 Lund VJ, Howard DJ, Wei WI (2014) Tumors oft he nose, sinuses, and nasopharynx. Thieme, Stuttgart, pp 137–150
34.
Zurück zum Zitat Simpson CL, Garabrant DH, Fryzek J, Homa DM, Peters RK (1998) Wood-dust exposures and cancer oft he colon. Int J Occup Environ Health 4:179–183CrossRefPubMed Simpson CL, Garabrant DH, Fryzek J, Homa DM, Peters RK (1998) Wood-dust exposures and cancer oft he colon. Int J Occup Environ Health 4:179–183CrossRefPubMed
35.
Zurück zum Zitat Innos K, Rahu M, Rahu K et al (2000) Wood dust exposure and cancer incidence: a retrospective cohort study of furniture workers in Estonia. Am J Ind Med 37:501–511CrossRefPubMed Innos K, Rahu M, Rahu K et al (2000) Wood dust exposure and cancer incidence: a retrospective cohort study of furniture workers in Estonia. Am J Ind Med 37:501–511CrossRefPubMed
Metadaten
Titel
Clinical and morphological aspects of adenocarcinomas of the intestinal type in the inner nose: a retrospective multicenter analysis
verfasst von
K. Donhuijsen
I. Kollecker
P. Petersen
N. Gaßler
J. Wolf
H.-G. Schroeder
Publikationsdatum
04.04.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Oto-Rhino-Laryngology / Ausgabe 10/2016
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-016-3987-4

Weitere Artikel der Ausgabe 10/2016

European Archives of Oto-Rhino-Laryngology 10/2016 Zur Ausgabe

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

HNO-Op. auch mit über 90?

16.04.2024 HNO-Chirurgie Nachrichten

Mit Blick auf das Risiko für Komplikationen nach elektiven Eingriffen im HNO-Bereich scheint das Alter der Patienten kein ausschlaggebender Faktor zu sein. Entscheidend ist offenbar, wie fit die Betroffenen tatsächlich sind.

Intrakapsuläre Tonsillektomie gewinnt an Boden

16.04.2024 Tonsillektomie Nachrichten

Gegenüber der vollständigen Entfernung der Gaumenmandeln hat die intrakapsuläre Tonsillektomie einige Vorteile, wie HNO-Fachleute aus den USA hervorheben. Sie haben die aktuelle Literatur zu dem Verfahren gesichtet.

Bilateraler Hörsturz hat eine schlechte Prognose

15.04.2024 Hörsturz Nachrichten

Die Mehrzahl der Menschen mit Hörsturz ist einseitig betroffen, doch auch ein beidseitiger Hörsturz ist möglich. Wie häufig solche Fälle sind und wie sich ihr Verlauf darstellt, hat eine HNO-Expertenrunde aus den USA untersucht.

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.