Ausgabe 8/2018
Inhalt (12 Artikel)
Industry Perspective on Standardizing Food-Effect Studies for New Drug Development
Patrick J. Marroum, Silpa Nuthalapati, Apurvasena Parikh, Mohamad Shebley, David Hoffman, Jiuhong Zha, Amit Khatri, Walid M. Awni
Daclatasvir: A Review of Preclinical and Clinical Pharmacokinetics
Yash Gandhi, Timothy Eley, Aberra Fura, Wenying Li, Richard J. Bertz, Tushar Garimella
Clinical Pharmacokinetics and Pharmacodynamics of Infliximab in the Treatment of Inflammatory Bowel Disease
Amy Hemperly, Niels Vande Casteele
Methods of Estimating Kidney Function for Drug Dosing in Special Populations
Laura A. Hart, Gail D. Anderson
Population Pharmacokinetics of Upadacitinib in Healthy Subjects and Subjects with Rheumatoid Arthritis: Analyses of Phase I and II Clinical Trials
Ben Klünder, Mohamed-Eslam F. Mohamed, Ahmed A. Othman
Population Pharmacokinetics and Dosing Considerations for the Use of Linezolid in Overweight and Obese Adult Patients
Piergiorgio Cojutti, Manjunath P. Pai, Federico Pea
Characterization of the Pharmacokinetics of Vilaprisan: Bioavailability, Excretion, Biotransformation, and Drug–Drug Interaction Potential
Marcus-Hillert Schultze-Mosgau, Joachim Höchel, Olaf Prien, Torsten Zimmermann, Ashley Brooks, Jim Bush, Antje Rottmann
Evaluation of Tobramycin Exposure Predictions in Three Bayesian Forecasting Programmes Compared with Current Clinical Practice in Children and Adults with Cystic Fibrosis
Marc Burgard, Indy Sandaradura, Sebastiaan J. van Hal, Sonya Stacey, Stefanie Hennig
Pharmacokinetic and Pharmacodynamic Modelling to Characterize the Tolerability of Alternative Up-Titration Regimens of Roflumilast in Patients with Chronic Obstructive Pulmonary Disease
Axel Facius, Eleonora Marostica, Philip Gardiner, Henrik Watz, Gezim Lahu
Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials
Sven C. van Dijkman, Nico C. B. de Jager, Willem M. Rauwé, Meindert Danhof, Oscar Della Pasqua
Correction to: Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials
Sven C. van Dijkman, Nico C. B. de Jager, Willem M. Rauwé, Meindert Danhof, Oscar Della Pasqua
Correction to: Clinical Pharmacokinetic Characteristics of Cebranopadol, a Novel First-in-Class Analgesic
Elke Kleideiter, Chiara Piana, Shaonan Wang, Robert Nemeth, Michael Gautrois