nach oben

Supportive Care in Cancer

Erschienen in:

09.08.2021 | Original Article

Cognitive skill training improves memory, function, and use of cognitive strategies in cancer survivors

verfasst von: Monique M. Cherrier, Celestia S. Higano, Heidi J. Gray

Erschienen in: Supportive Care in Cancer | Ausgabe 1/2022

Einloggen, um Zugang zu erhalten

Abstract

Background

Cancer survivors commonly report symptoms of impaired cognition. This project examined effectiveness of a behavioral skills training intervention to improve cognition and reduce cognitive dysfunction symptoms in cancer survivors.

Methods

Participants were randomly assigned to group-based workshops focused on learning new cognitive skills (skills treatment—TX) or an active control of education workshops (education control—EC) or a passive control of wait list (WL). Participants were evaluated pre- and post intervention with subjective mood and symptom questionnaires and objective neurocognitive tests.

Results

One hundred twenty-eight participants (mean age 59 years), average 4.6 years (+ / − 5.5 years) post cancer treatment with various cancer types (breast, bladder, prostate, colon, uterine), were enrolled. Analysis of all participants who attended workshop(s) revealed improvement in the TX workshop completers on all objective cognitive measures (attention, concentration, declarative, and working memory) save one test of selective attention, and improvement on a single measure (verbal memory) and decline (selective attention) in the EC group. TX workshop completers also improved on all symptom and mood measures, in contrast to EC group which improved on a single subscale of a symptom measure, but increased on an anxiety measure. TX group alone improved on a quantified measure of each participants’ unique, “top three,” self-described cognitive symptoms.

Conclusion

Improvement from behavioral skills training was evident from objective cognitive tests, subjective symptom measures, and quantified, individual patient-specific symptoms. Behavioral skill training is an effective treatment for cognitive dysfunction in cancer survivors, and should be considered as a treatment option by health care providers.

Nur mit Berechtigung zugänglich

Bradley CJ, Neumark D, Luo Z, Schenk M (2007) Employment and cancer: findings from a longitudinal study of breast and prostate cancer survivors. Cancer Invest 25:47–54. https://doi.org/10.1080/07357900601130664CrossRefPubMed

Ehrenstein JK, van Zon SKR, Duijts SFA, van Dijk BAC, Dorland HF, Schagen SB, Bultmann U (2020) Type of cancer treatment and cognitive symptoms in working cancer survivors: an 18-month follow-up study. J Cancer Surviv 14:158–167. https://doi.org/10.1007/s11764-019-00839-wCrossRefPubMedPubMedCentral

Von Ah D, Storey S, Crouch A (2018) Relationship between self-reported cognitive function and work-related outcomes in breast cancer survivors. J Cancer Surviv 12:246–255. https://doi.org/10.1007/s11764-017-0664-6CrossRef

Lange M, Joly F, Vardy J, Ahles T, Dubois M, Tron L, Winocur G, De Ruiter MB, Castel H (2019) Cancer-related cognitive impairment: an update on state of the art, detection, and management strategies in cancer survivors. Ann Oncol 30:1925–1940CrossRef

Von Ah D, Crouch A (2020) Cognitive rehabilitation for cognitive dysfunction after cancer and cancer treatment: implications for nursing practice. Semin Oncol Nurs 36, <Go to ISI>://WOS:000517834200004

Vance DE, Frank JS, Bail J, Triebel KL, Niccolai LM, Gerstenecker A, Meneses K (2017) Interventions for cognitive deficits in breast cancer survivors treated with chemotherapy. Cancer Nurs 40:E11–E27. https://doi.org/10.1097/NCC.0000000000000349CrossRefPubMed

Ercoli LM, Petersen L, Hunter AM et al (2015) Cognitive rehabilitation group intervention for breast cancer survivors: results of a randomized clinical trial. Psychooncology 24:1360–1367. https://doi.org/10.1002/pon.3769CrossRefPubMed

Ferguson RJ, McDonald BC, Rocque MA, Furstenberg CT, Horrigan S, Ahles TA, Saykin AJ (2012) Development of CBT for chemotherapy-related cognitive change: results of a waitlist control trial. Psychooncology 21:176–186. https://doi.org/10.1002/pon.1878CrossRefPubMed

King S, Green HJ (2015) Psychological intervention for improving cognitive function in cancer survivors: a literature review and randomized controlled trial. Front Oncol 5:72. https://doi.org/10.3389/fonc.2015.00072CrossRefPubMedPubMedCentral

10.

Schuurs A, Green HJ (2013) A feasibility study of group cognitive rehabilitation for cancer survivors: enhancing cognitive function and quality of life. Psychooncology 22:1043–1049. https://doi.org/10.1002/pon.3102CrossRefPubMed

11.

Poppelreuter M, Weis J, Bartsch HH (2009) Effects of specific neuropsychological training programs for breast cancer patients after adjuvant chemotherapy. J Psychosoc Oncol 27:274–296. https://doi.org/10.1080/07347330902776044CrossRefPubMed

12.

Von Ah D, Carpenter JS, Saykin A et al (2012) Advanced cognitive training for breast cancer survivors: a randomized controlled trial. Breast Cancer Res Treat 135:799–809. https://doi.org/10.1007/s10549-012-2210-6CrossRef

13.

Asher A, Dyk K, Jo MY, Bailey C, Myers JS (2019) Cancer-related cognitive impairment: retrospective analyses of a multidimensional, psychoeducation-based cognitive rehabilitation intervention. Clin J Oncol Nurs 23:301–308. https://doi.org/10.1188/19.CJON.301-308CrossRefPubMed

14.

Zeng Y, Cheng AS, Chan CC (2016) Meta-analysis of the effects of neuropsychological interventions on cognitive function in non-central nervous system cancer survivors. Integr Cancer Ther 15:424–434. https://doi.org/10.1177/1534735416638737CrossRefPubMedPubMedCentral

15.

Beglinger LJ, Gaydos B, Tangphao-Daniels O, Duff K, Kareken DA, Crawford J, Fastenau PS, Siemers ER (2005) Practice effects and the use of alternate forms in serial neuropsychological testing. Arch Clin Neuropsychol 20:517–529. https://doi.org/10.1016/j.acn.2004.12.003CrossRefPubMed

16.

Spielmans GI, Fluckiger C (2018) Moderators in psychotherapy meta-analysis. Psychother Res 28:333–346. https://doi.org/10.1080/10503307.2017.1422214CrossRefPubMed

17.

Rains JC, Penzien DB (2005) Behavioral research and the double-blind placebo-controlled methodology: challenges in applying the biomedical standard to behavioral headache research. Headache 45:479–486. https://doi.org/10.1111/j.1526-4610.2005.05099.xCrossRefPubMed

18.

Hursey KG, Rains JC, Penzien DB, Nash JM, Nicholson RA (2005) Behavioral headache research: methodologic considerations and research design alternatives. Headache 45:466–478. https://doi.org/10.1111/j.1526-4610.2005.05098.xCrossRefPubMed

19.

Wittkampf K, van Ravesteijn H, Baas K, van de Hoogen H, Schene A, Bindels P, Lucassen P, van de Lisdonk E, van Weert H (2009) The accuracy of Patient Health Questionnaire-9 in detecting depression and measuring depression severity in high-risk groups in primary care. Gen Hosp Psychiatry 31:451–459

20.

Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198CrossRef

21.

Ward MF, Wender PH, Reimherr FW (1993) The Wender Utah Rating Scale: an aid in the retrospective diagnosis of childhood attention deficit hyperactivity disorder. Am J Psychiatry 150: 885–890, http://www.ncbi.nlm.nih.gov/pubmed/8494063

22.

Cacioppo JT, Petty RE, Kao CF (1984) The efficient assessment of need for cognition. J Pers Assess 48:306–307. https://doi.org/10.1207/s15327752jpa4803_13CrossRefPubMed

23.

Dweck C (1999) Self-theories: their role in motivation, personality, and development. Psychology Press, Philadelphia

24.

Mcconnaughy EA, Prochaska JO, Velicer WF (1983) Stages of change in psychotherapy—measurement and sample profiles. Psychother-Theor Res 20:368–375. https://doi.org/10.1037/h0090198CrossRef

25.

Wechsler (2001) Wechsler Test of Adult Reading (Manual). The Psychological Corporation, San Antonio, TX

26.

Cherrier M (2020) Cares study overview, osf.io/y83bd

27.

Jacobs SR, Jacobsen PB, Booth-Jones M, Wagner LI, Anasetti C (2007) Evaluation of the functional assessment of cancer therapy cognitive scale with hematopoietic stem cell transplant patients. J Pain Symptom Manage 33: 13–23, http://www.ncbi.nlm.nih.gov/PubMed/17196903

28.

Wittkampf KA, Naeije L, Schene AH, Huyser J, van Weert HC (2007) Diagnostic accuracy of the mood module of the Patient Health Questionnaire: a systematic review. Gen Hosp Psychiatry 29: 388–395, http://www.ncbi.nlm.nih.gov/PubMed/17888804

29.

Stanley MA, Beck JG, Zebb BJ (1996) Psychometric properties of four anxiety measures in older adults. Behav Res Ther 34:827–838CrossRef

30.

Cella DF (1997) Manual of the Functional Assessment of Chronic Illness Therapy (FACIT Scales) - Version 4. Center on Outcomes Research and Education (CORE), Evanston, IL

31.

Cimprich B, Visovatti M, Ronis DL (2011) The Attentional Function Index—a self-report cognitive measure. Psychooncology 20:194–202. https://doi.org/10.1002/pon.1729CrossRefPubMed

32.

Troyer AK, Rich JB (2002) Psychometric properties of a new metamemory questionnaire for older adults. The journals of gerontology Series B, Psychological sciences and social sciences 57: P19–27, http://www.ncbi.nlm.nih.gov/pubmed/11773220

33.

Chelune GJH, Robert K. Lehman, Ralph A. W. (1986) Neuropsychological and personality correlates of patients’ complaints of disability. In: Editor (ed)^(eds) Book Neuropsychological and Personality Correlates of Patients’ Complaints of Disability. Advances in Clinical Neuropsychology, City, pp. 95–126,

34.

Wechsler D (1997) WAIS-III administration and scoring manual. The Psychological Corporation, San Antonio, TX

35.

Delis DC, Kaplan E, Kramer J (2001) Delis-Kaplan executive function system. Psychological Corporation, San Antonio, TX

36.

Schmidt M (1996) Rey auditory verbal learning test: a handbook. Western Psychological Services, Los Angeles, CA

37.

Sullivan K (2005) Alternate forms of prose passages for the assessment of auditory-verbal memory Arch Clin Neuropsychol 20: 745–753, http://www.ncbi.nlm.nih.gov/PubMed/16005816

38.

Wechsler D (1997) Wechsler Memory Scale III. The Psychological Corporation, San Antonio, TX

39.

Gajewski PD, Falkenstein M (2012) Training-induced improvement of response selection and error detection in aging assessed by task switching: effects of cognitive, physical, and relaxation training. Front Hum Neurosci 6:130. https://doi.org/10.3389/fnhum.2012.00130CrossRefPubMedPubMedCentral

40.

Greenaway MC, Duncan NL, Smith GE (2012) The memory support system for mild cognitive impairment: randomized trial of a cognitive rehabilitation intervention. Int J Geriatr Psychiatry. https://doi.org/10.1002/gps.3838CrossRefPubMedPubMedCentral

41.

Gross AL, Parisi JM, Spira AP, Kueider AM, Ko JY, Saczynski JS, Samus QM, Rebok GW (2012) Memory training interventions for older adults: a meta-analysis. Aging Ment Health 16:722–734. https://doi.org/10.1080/13607863.2012.667783CrossRefPubMedPubMedCentral

42.

Jones RN, Marsiske M, Ball K, Rebok G, Willis SL, Morris JN, Tennstedt SL (2012) The ACTIVE cognitive training interventions and trajectories of performance among older adults. J Aging Health. https://doi.org/10.1177/0898264312461938CrossRefPubMedPubMedCentral

43.

IBM (2019) SPSS Statistics, Version 26. . In: Editor (ed)^(eds) Book SPSS Statistics, Version 26. . IBM Corporation, City,

44.

Mihuta ME, Green HJ, Shum DHK (2018) Efficacy of a web-based cognitive rehabilitation intervention for adult cancer survivors: a pilot study. Eur J Cancer Care (Engl) 27:e12805. https://doi.org/10.1111/ecc.12805CrossRef

45.

Wefel JS, Saleeba AK, Buzdar AU, Meyers CA (2010) Acute and late onset cognitive dysfunction associated with chemotherapy in women with breast cancer. Cancer 116:3348–3356. https://doi.org/10.1002/cncr.25098CrossRefPubMed

46.

Ganz PA, Kwan L, Castellon SA et al (2013) Cognitive complaints after breast cancer treatments: examining the relationship with neuropsychological test performance. J Natl Cancer Inst 105:791–801. https://doi.org/10.1093/jnci/djt073CrossRefPubMedPubMedCentral

47.

Lee RSC, Hermens DF, Porter MA, Redoblado-Hodge MA (2012) A meta-analysis of cognitive deficits in first-episode. Major Depress Disord J Affect Disord 140:113–124. https://doi.org/10.1016/j.jad.2011.10.023CrossRef

48.

Panza F, D’Introno A, Colacicco AM et al (2009) Temporal relationship between depressive symptoms and cognitive impairment: the Italian longitudinal study on aging. J Alzheimers Dis 17:899–911. https://doi.org/10.3233/jad-2009-1111CrossRefPubMed

Titel: Cognitive skill training improves memory, function, and use of cognitive strategies in cancer survivors
verfasst von: Monique M. Cherrier
Celestia S. Higano
Heidi J. Gray
Publikationsdatum: 09.08.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 1/2022
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-021-06453-w

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Cognitive skill training improves memory, function, and use of cognitive strategies in cancer survivors

Abstract

Background

Methods

Results

Conclusion

Neu im Fachgebiet Onkologie

Erhöhtes Risiko fürs Herz unter Checkpointhemmer-Therapie

Costims – das nächste heiße Ding in der Krebstherapie?

Perioperative Checkpointhemmer-Therapie verbessert NSCLC-Prognose

Positiver FIT: Die Ursache liegt nicht immer im Dickdarm

Update Onkologie

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Background

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2022

Factors associated with sleep disturbances in women undergoing treatment for early-stage breast cancer

Correlates of fatigue severity in patients with chronic myeloid leukemia treated with targeted therapy

An educational bereavement program to decrease clinical staff’s barriers and improve self-efficacy of providing bereavement care

Mapping childcare support for patients at a sample of North American hospitals and cancer centers: an environmental scan

Acceptance- and mindfulness-based techniques for physical activity promotion in breast cancer survivors: a qualitative study

Letter to the editor referencing “Body composition changes in patients with head and neck cancer under active treatment: a scoping review”

Neu im Fachgebiet Onkologie

Erhöhtes Risiko fürs Herz unter Checkpointhemmer-Therapie

Costims – das nächste heiße Ding in der Krebstherapie?

Perioperative Checkpointhemmer-Therapie verbessert NSCLC-Prognose

Positiver FIT: Die Ursache liegt nicht immer im Dickdarm

Update Onkologie