Erschienen in:
17.12.2018 | Editorial
Coming Complications of Nonalcoholic Fatty Liver Disease: Time to GNASH Your Teeth
verfasst von:
Clara E. Dismuke-Greer, Wing-Kin Syn
Erschienen in:
Digestive Diseases and Sciences
|
Ausgabe 3/2019
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Excerpt
Nonalcoholic fatty liver disease (NAFLD), the leading cause of chronic liver disease in the USA and in other developed nations, is associated with metabolic risk factors including obesity, type 2 diabetes mellitus (T2DM), dyslipidemia, hypertension, and “non-classical” risk factors such as obstructive sleep apnea and gout [
1]. In the USA, the true prevalence of NAFLD is 25–40%, depending on the modalities used to diagnosis NAFLD, and is in parallel with the rising tide of obesity and T2DM [
2,
3]. As cardiovascular disease and extrahepatic cancers are the most common causes of death among those with NAFLD [
4,
5], NAFLD is now considered a multi-systemic metabolic disease. …