Skip to main content
Erschienen in: Cardiovascular Intervention and Therapeutics 4/2022

25.01.2022 | Original Article

Comparison of medical resource use and total admission cost in patients with acute myocardial infarction between on-hours visit versus off-hours visit

verfasst von: Tsukasa Murakami, Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Takunori Tsukui, Yusuke Watanabe, Kei Yamamoto, Masaru Seguchi, Hiroshi Wada, Hideo Fujita

Erschienen in: Cardiovascular Intervention and Therapeutics | Ausgabe 4/2022

Einloggen, um Zugang zu erhalten

Abstract

The medical expenses for patients with acute myocardial infarction (AMI) has become enormous burden for global healthcare system. In AMI patients, total admission cost for patients with off-hours visit may be higher than those with on-hours visit, because of additional cost for emergent care during off-hours. This study aimed to compare total medical cost in AMI patients between on-hours visit versus off-hours visit. We retrospectively included 368 AMI patients who underwent PCI to the culprit lesion, and divided them into the on-hours group (n = 173) and the off-hours group (n = 195). We compared clinical characteristics, total admission cost, and clinical outcomes between the two groups. The prevalence of Killip class 3/4 was significantly greater in the off-hours group than in the on-hours group. Length of ICU and hospital stay were significantly longer in the off-hours group than in the on-hours group. Total admission cost was significantly higher in the off-hours group [¥1,570,400 (¥1,271,550–¥2,117,090)] than in the on-hours group [¥1,356,270 (¥1,100,990–¥1,957,225)] (P < 0.001). However, multivariate analysis revealed off-hours visit itself was not associated with high total admission cost after adjusting confounding factors. In conclusion, total admission cost was higher in AMI patients with off-hours visit than in those with on-hours visit. However, multivariate logistic regression analysis revealed that the off-hours visit itself was not associated with the highest total admission cost. Off-hours visit itself did not result in higher cost, but severer conditions in AMI patients with off-hours visit resulted in higher cost.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Jan S, Lee SW, Sawhney JPS, Ong TK, Chin CT, Kim HS, et al. Predictors of high-cost hospitalization in the treatment of acute coronary syndrome in Asia: findings from EPICOR Asia. BMC Cardiovasc Disord. 2018;18(1):139.CrossRef Jan S, Lee SW, Sawhney JPS, Ong TK, Chin CT, Kim HS, et al. Predictors of high-cost hospitalization in the treatment of acute coronary syndrome in Asia: findings from EPICOR Asia. BMC Cardiovasc Disord. 2018;18(1):139.CrossRef
2.
Zurück zum Zitat Soekhlal RR, Burgers LT, Redekop WK, Tan SS. Treatment costs of acute myocardial infarction in the Netherlands. Neth Heart J. 2013;21(5):230–5.CrossRef Soekhlal RR, Burgers LT, Redekop WK, Tan SS. Treatment costs of acute myocardial infarction in the Netherlands. Neth Heart J. 2013;21(5):230–5.CrossRef
3.
Zurück zum Zitat Bramkamp M, Radovanovic D, Erne P, Szucs TD. Determinants of costs and the length of stay in acute coronary syndromes: a real life analysis of more than 10,000 patients. Cardiovasc Drugs Ther. 2007;21(5):389–98.CrossRef Bramkamp M, Radovanovic D, Erne P, Szucs TD. Determinants of costs and the length of stay in acute coronary syndromes: a real life analysis of more than 10,000 patients. Cardiovasc Drugs Ther. 2007;21(5):389–98.CrossRef
4.
Zurück zum Zitat O’Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127(4):e362-425.PubMed O’Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127(4):e362-425.PubMed
5.
Zurück zum Zitat Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, et al. 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(25):e344-426.PubMed Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, et al. 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(25):e344-426.PubMed
6.
Zurück zum Zitat Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018;39(2):119–77.CrossRef Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018;39(2):119–77.CrossRef
7.
Zurück zum Zitat Collet JP, Thiele H, Barbato E, Barthelemy O, Bauersachs J, Bhatt DL, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2021;42(14):1289–367.CrossRef Collet JP, Thiele H, Barbato E, Barthelemy O, Bauersachs J, Bhatt DL, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2021;42(14):1289–367.CrossRef
8.
Zurück zum Zitat Lieu TA, Lundstrom RJ, Ray GT, Fireman BH, Gurley RJ, Parmley WW. Initial cost of primary angioplasty for acute myocardial infarction. J Am Coll Cardiol. 1996;28(4):882–9.CrossRef Lieu TA, Lundstrom RJ, Ray GT, Fireman BH, Gurley RJ, Parmley WW. Initial cost of primary angioplasty for acute myocardial infarction. J Am Coll Cardiol. 1996;28(4):882–9.CrossRef
9.
Zurück zum Zitat Khot UN, Johnson ML, Ramsey C, Khot MB, Todd R, Shaikh SR, et al. Emergency department physician activation of the catheterization laboratory and immediate transfer to an immediately available catheterization laboratory reduce door-to-balloon time in ST-elevation myocardial infarction. Circulation. 2007;116(1):67–76.CrossRef Khot UN, Johnson ML, Ramsey C, Khot MB, Todd R, Shaikh SR, et al. Emergency department physician activation of the catheterization laboratory and immediate transfer to an immediately available catheterization laboratory reduce door-to-balloon time in ST-elevation myocardial infarction. Circulation. 2007;116(1):67–76.CrossRef
10.
Zurück zum Zitat Kostis WJ, Demissie K, Marcella SW, Shao YH, Wilson AC, Moreyra AE. Weekend versus weekday admission and mortality from myocardial infarction. N Engl J Med. 2007;356(11):1099–109.CrossRef Kostis WJ, Demissie K, Marcella SW, Shao YH, Wilson AC, Moreyra AE. Weekend versus weekday admission and mortality from myocardial infarction. N Engl J Med. 2007;356(11):1099–109.CrossRef
11.
Zurück zum Zitat Ikegami N, Yoo B-K, Hashimoto H, Matsumoto M, Ogata H, Babazono A, et al. Japanese universal health coverage: evolution, achievements, and challenges. The Lancet. 2011;378(9796):1106–15.CrossRef Ikegami N, Yoo B-K, Hashimoto H, Matsumoto M, Ogata H, Babazono A, et al. Japanese universal health coverage: evolution, achievements, and challenges. The Lancet. 2011;378(9796):1106–15.CrossRef
13.
Zurück zum Zitat Kanaoka K, Okayama S, Nakai M, Sumita Y, Nishimura K, Kawakami R, et al. Hospitalization costs for patients with acute congestive heart failure in Japan. Circ J. 2019;83(5):1025–31.CrossRef Kanaoka K, Okayama S, Nakai M, Sumita Y, Nishimura K, Kawakami R, et al. Hospitalization costs for patients with acute congestive heart failure in Japan. Circ J. 2019;83(5):1025–31.CrossRef
14.
Zurück zum Zitat Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). J Am Coll Cardiol. 2018;72(18):2231–64.CrossRef Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). J Am Coll Cardiol. 2018;72(18):2231–64.CrossRef
15.
Zurück zum Zitat Sakakura K, Ako J, Wada H, Kubo N, Momomura S. ACC/AHA classification of coronary lesions reflects medical resource use in current percutaneous coronary interventions. Catheter Cardiovasc Interv. 2012;80(3):370–6.CrossRef Sakakura K, Ako J, Wada H, Kubo N, Momomura S. ACC/AHA classification of coronary lesions reflects medical resource use in current percutaneous coronary interventions. Catheter Cardiovasc Interv. 2012;80(3):370–6.CrossRef
16.
Zurück zum Zitat Garg S, Sarno G, Serruys PW, Rodriguez AE, Bolognese L, Anselmi M, et al. Prediction of 1-year clinical outcomes using the SYNTAX score in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study) trials. JACC Cardiovasc Interv. 2011;4(1):66–75.CrossRef Garg S, Sarno G, Serruys PW, Rodriguez AE, Bolognese L, Anselmi M, et al. Prediction of 1-year clinical outcomes using the SYNTAX score in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study) trials. JACC Cardiovasc Interv. 2011;4(1):66–75.CrossRef
17.
Zurück zum Zitat Uemura S, Okamoto H, Nakai M, Nishimura K, Miyamoto Y, Yasuda S, et al. Primary percutaneous coronary intervention in elderly patients with acute myocardial infarction—an analysis from a Japanese Nationwide Claim-Based Database. Circ J. 2019;83(6):1229–38.CrossRef Uemura S, Okamoto H, Nakai M, Nishimura K, Miyamoto Y, Yasuda S, et al. Primary percutaneous coronary intervention in elderly patients with acute myocardial infarction—an analysis from a Japanese Nationwide Claim-Based Database. Circ J. 2019;83(6):1229–38.CrossRef
18.
Zurück zum Zitat Burgess SN, Juergens CP, Nguyen TL, Leung M, Robledo KP, Thomas L, et al. Comparison of late cardiac death and myocardial infarction rates in women vs men with ST-elevation myocardial infarction. Am J Cardiol. 2020;128:120–6.CrossRef Burgess SN, Juergens CP, Nguyen TL, Leung M, Robledo KP, Thomas L, et al. Comparison of late cardiac death and myocardial infarction rates in women vs men with ST-elevation myocardial infarction. Am J Cardiol. 2020;128:120–6.CrossRef
19.
Zurück zum Zitat Song YB, Hahn JY, Kim JH, Lee SY, Choi SH, Choi JH, et al. Comparison of angiographic and other findings and mortality in non-ST-segment elevation versus ST-segment elevation myocardial infarction in patients undergoing early invasive intervention. Am J Cardiol. 2010;106(10):1397–403.CrossRef Song YB, Hahn JY, Kim JH, Lee SY, Choi SH, Choi JH, et al. Comparison of angiographic and other findings and mortality in non-ST-segment elevation versus ST-segment elevation myocardial infarction in patients undergoing early invasive intervention. Am J Cardiol. 2010;106(10):1397–403.CrossRef
20.
Zurück zum Zitat Itzahki Ben Zadok O, Ben-Gal T, Abelow A, Shechter A, Zusman O, Iakobishvili Z, et al. Temporal trends in the characteristics. Management and outcomes of patients with acute coronary syndrome according to their Killip class. Am J Cardiol. 2019;124(12):1862–8.CrossRef Itzahki Ben Zadok O, Ben-Gal T, Abelow A, Shechter A, Zusman O, Iakobishvili Z, et al. Temporal trends in the characteristics. Management and outcomes of patients with acute coronary syndrome according to their Killip class. Am J Cardiol. 2019;124(12):1862–8.CrossRef
21.
Zurück zum Zitat Mazurek M, Kowalczyk J, Lenarczyk R, Swiatkowski A, Kowalski O, Sedkowska A, et al. The impact of unsuccessful percutaneous coronary intervention on short- and long-term prognosis in STEMI and NSTEMI. Catheter Cardiovasc Interv. 2011;78(4):514–22.CrossRef Mazurek M, Kowalczyk J, Lenarczyk R, Swiatkowski A, Kowalski O, Sedkowska A, et al. The impact of unsuccessful percutaneous coronary intervention on short- and long-term prognosis in STEMI and NSTEMI. Catheter Cardiovasc Interv. 2011;78(4):514–22.CrossRef
22.
Zurück zum Zitat Sasaki N, Kunisawa S, Ikai H, Imanaka Y. Differences between determinants of in-hospital mortality and hospitalisation costs for patients with acute heart failure: a nationwide observational study from Japan. BMJ Open. 2017;7(3): e013753.CrossRef Sasaki N, Kunisawa S, Ikai H, Imanaka Y. Differences between determinants of in-hospital mortality and hospitalisation costs for patients with acute heart failure: a nationwide observational study from Japan. BMJ Open. 2017;7(3): e013753.CrossRef
23.
Zurück zum Zitat Matsui K, Kojima S, Sakamoto T, Ishihara M, Kimura K, Miyazaki S, et al. Weekend onset of acute myocardial infarction does not have a negative impact on outcome in Japan. Circ J. 2007;71(12):1841–4.CrossRef Matsui K, Kojima S, Sakamoto T, Ishihara M, Kimura K, Miyazaki S, et al. Weekend onset of acute myocardial infarction does not have a negative impact on outcome in Japan. Circ J. 2007;71(12):1841–4.CrossRef
24.
Zurück zum Zitat Ogita M, Suwa S, Ebina H, Nakao K, Ozaki Y, Kimura K, et al. Off-hours presentation does not affect in-hospital mortality of Japanese patients with acute myocardial infarction: J-MINUET substudy. J Cardiol. 2017;70(6):553–8.CrossRef Ogita M, Suwa S, Ebina H, Nakao K, Ozaki Y, Kimura K, et al. Off-hours presentation does not affect in-hospital mortality of Japanese patients with acute myocardial infarction: J-MINUET substudy. J Cardiol. 2017;70(6):553–8.CrossRef
25.
Zurück zum Zitat Suwa S, Ogita M, Ebina H, Nakao K, Ozaki Y, Kimura K, et al. Admission during off-hours does not affect long-term clinical outcomes of Japanese patients with acute myocardial infarction. Int Heart J. 2020;61(2):215–22.CrossRef Suwa S, Ogita M, Ebina H, Nakao K, Ozaki Y, Kimura K, et al. Admission during off-hours does not affect long-term clinical outcomes of Japanese patients with acute myocardial infarction. Int Heart J. 2020;61(2):215–22.CrossRef
26.
Zurück zum Zitat Zeymer U, Hochadel M, Karcher AK, Thiele H, Darius H, Behrens S, et al. Procedural success rates and mortality in elderly patients with percutaneous coronary intervention for cardiogenic shock. JACC Cardiovasc Interv. 2019;12(18):1853–9.CrossRef Zeymer U, Hochadel M, Karcher AK, Thiele H, Darius H, Behrens S, et al. Procedural success rates and mortality in elderly patients with percutaneous coronary intervention for cardiogenic shock. JACC Cardiovasc Interv. 2019;12(18):1853–9.CrossRef
27.
Zurück zum Zitat Shiraishi J, Kohno Y, Nakamura T, Yanagiuchi T, Hashimoto S, Ito D, et al. Predictors of in-hospital outcomes after primary percutaneous coronary intervention for acute myocardial infarction in patients with a high Killip class. Intern Med. 2014;53(9):933–9.CrossRef Shiraishi J, Kohno Y, Nakamura T, Yanagiuchi T, Hashimoto S, Ito D, et al. Predictors of in-hospital outcomes after primary percutaneous coronary intervention for acute myocardial infarction in patients with a high Killip class. Intern Med. 2014;53(9):933–9.CrossRef
Metadaten
Titel
Comparison of medical resource use and total admission cost in patients with acute myocardial infarction between on-hours visit versus off-hours visit
verfasst von
Tsukasa Murakami
Kenichi Sakakura
Hiroyuki Jinnouchi
Yousuke Taniguchi
Takunori Tsukui
Yusuke Watanabe
Kei Yamamoto
Masaru Seguchi
Hiroshi Wada
Hideo Fujita
Publikationsdatum
25.01.2022
Verlag
Springer Nature Singapore
Erschienen in
Cardiovascular Intervention and Therapeutics / Ausgabe 4/2022
Print ISSN: 1868-4300
Elektronische ISSN: 1868-4297
DOI
https://doi.org/10.1007/s12928-022-00838-2

Weitere Artikel der Ausgabe 4/2022

Cardiovascular Intervention and Therapeutics 4/2022 Zur Ausgabe

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

17.05.2024 Plötzlicher Herztod Nachrichten

Ein signifikanter Anteil der Fälle von plötzlichem Herztod ist genetisch bedingt. Um ihre Verwandten vor diesem Schicksal zu bewahren, sollten jüngere Personen, die plötzlich unerwartet versterben, ausnahmslos einer Autopsie unterzogen werden.

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Schlechtere Vorhofflimmern-Prognose bei kleinem linken Ventrikel

17.05.2024 Vorhofflimmern Nachrichten

Nicht nur ein vergrößerter, sondern auch ein kleiner linker Ventrikel ist bei Vorhofflimmern mit einer erhöhten Komplikationsrate assoziiert. Der Zusammenhang besteht nach Daten aus China unabhängig von anderen Risikofaktoren.

Semaglutid bei Herzinsuffizienz: Wie erklärt sich die Wirksamkeit?

17.05.2024 Herzinsuffizienz Nachrichten

Bei adipösen Patienten mit Herzinsuffizienz des HFpEF-Phänotyps ist Semaglutid von symptomatischem Nutzen. Resultiert dieser Benefit allein aus der Gewichtsreduktion oder auch aus spezifischen Effekten auf die Herzinsuffizienz-Pathogenese? Eine neue Analyse gibt Aufschluss.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.