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Journal of Natural Medicines

Erschienen in:

01.04.2016 | Note

Composition of the endophytic filamentous fungi associated with Cinchona ledgeriana seeds and production of Cinchona alkaloids

verfasst von: Shoji Maehara, Andria Agusta, Chinami Kitamura, Kazuyoshi Ohashi, Hirotaka Shibuya

Erschienen in: Journal of Natural Medicines | Ausgabe 2/2016

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Abstract

Four kinds of endophytic filamentous fungi (code names: CLS-1, CLS-2, CLS-3, and CLS-4) associated with the seeds of Cinchona ledgeriana (Rubiaceae) from West Java, Indonesia, were isolated. All of the isolates were classified into Diaporthe spp. based on phylogenetic analysis of the nucleotide sequences of the internal transcribed spacers (ITS1 and ITS2) including the 5.8S ribosomal DNA region. All four of these endophytic fungi produce Cinchona alkaloids, mainly quinine and quinidine, in synthetic liquid medium.

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Titel: Composition of the endophytic filamentous fungi associated with Cinchona ledgeriana seeds and production of Cinchona alkaloids
verfasst von: Shoji Maehara
Andria Agusta
Chinami Kitamura
Kazuyoshi Ohashi
Hirotaka Shibuya
Publikationsdatum: 01.04.2016
Verlag: Springer Japan
Erschienen in: Journal of Natural Medicines / Ausgabe 2/2016
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-015-0954-0

Springer Medizin

Abstract

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