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29.06.2022 | Hepatobiliary

Computed diffusion-weighted magnetic resonance imaging with high b-values in the diagnosis of gallbladder lesions

verfasst von: Motokazu Sato, Yusuke Kurita, Eiji Sakai, Seitaro Watanabe, Haruto Sanada, Tomoki Shimizu, Kenji Kanoshima, Yusuke Takai, Koki Meguro, Yuichi Sugimoto, Yusuke Biwata, Kunihiro Hosono, Noritoshi Kobayashi, Kensuke Kubota, Atsushi Nakajima

Erschienen in: Abdominal Radiology | Ausgabe 9/2022

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Abstract

Purpose

The diagnosis of gallbladder lesions remains challenging. The efficacy of computed diffusion-weighted imaging (DWI) with high b-values and apparent diffusion coefficient (ADC) for the diagnosis of gallbladder cancer remains unknown. We aimed to investigate the usefulness of computed DWI with high b-values and the combination of computed DWI and ADC in differentiating malignant and benign gallbladder lesions.

Methods

Sixty patients (comprising 30 malignant and 30 benign lesions) who underwent magnetic resonance imaging for gallbladder lesions were included in this retrospective study. Qualitative evaluations were performed using conventional DWI with b1000, computed DWI with b1500, b1000 DWI/ADC, and computed b1500 DWI/ADC, and their diagnostic performances were compared.

Results

The sensitivity, specificity, and accuracy of computed b1500 DWI/ADC were 90% (27/30), 80% (24/30), and 85% (51/60), respectively. The accuracy of computed b1500 DWI/ADC was higher than that of conventional b1000 DWI (52%, 31/60, p < 0.001), computed b1500 DWI (72%, 43/60, p = 0.008), and b1000 DWI/ADC (78%, 47/60, p = 0.125). The specificity of computed b1500 DWI/ADC was also higher than that of conventional b1000 DWI (7%, 2/30, p < 0.001), computed b1500 DWI (47%, 14/30, p = 0.002), and b1000 DWI/ADC (67%, 20/30, p = 0.125). No significant difference was observed in the sensitivity between the groups.

Conclusion

This study shows that computed DWI with high b-values combined with ADC can improve diagnostic performance when differentiating malignant and benign gallbladder lesions.

Graphical abstract

Computed diffusion-weighted magnetic resonance imaging with high b-values in the diagnosis of gallbladder lesions.

*Computed DWI with b1500 combined with ADC can improve diagnostic performance when differentiating gallbladder lesions compared with conventional methods (b1000 DWI).

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Titel: Computed diffusion-weighted magnetic resonance imaging with high b-values in the diagnosis of gallbladder lesions
verfasst von: Motokazu Sato
Yusuke Kurita
Eiji Sakai
Seitaro Watanabe
Haruto Sanada
Tomoki Shimizu
Kenji Kanoshima
Yusuke Takai
Koki Meguro
Yuichi Sugimoto
Yusuke Biwata
Kunihiro Hosono
Noritoshi Kobayashi
Kensuke Kubota
Atsushi Nakajima
Publikationsdatum: 29.06.2022
Verlag: Springer US
Erschienen in: Abdominal Radiology / Ausgabe 9/2022
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-022-03586-2

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Computed diffusion-weighted magnetic resonance imaging with high b-values in the diagnosis of gallbladder lesions