Erschienen in:
01.11.2014
Conversion in endometrial cancer patients scheduled for laparoscopic staging: a large multicenter analysis
Conversions and endometrial cancer
verfasst von:
Stefano Palomba, Fabio Ghezzi, Angela Falbo, Vincenzo Dario Mandato, Gianluca Annunziata, Emilio Lucia, Antonella Cromi, Letizia Zannoni, Renato Seracchioli, Giorgio Giorda, Giovanni Battista La Sala, Fulvio Zullo, Massimo Franchi
Erschienen in:
Surgical Endoscopy
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Ausgabe 11/2014
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Abstract
Background
Data on patients with endometrial cancer converted to laparotomy are totally lacking. The aim of the present study was to evaluate surgical and oncological outcomes in patients with endometrial cancer scheduled for laparoscopic staging but converted to laparotomy.
Methods
Data of consecutive patients who had undergone surgery for staging endometrial cancer in seven Italian centers were reviewed. Patients’ characteristics and surgical and oncological data were noted and analyzed according to surgery, i.e. laparotomy, laparoscopy, and laparoscopy converted to laparotomy.
Results
Seventy-one out of 512 (13.9 %) patients scheduled to laparoscopy were converted to laparotomy for reasons related to anesthesiology [38/71 (53.5 %)] or surgery [33/71 (46.5 %)]. The conversion rate varied among stages [41/460 (8.9 %), 13/27 (48.1 %), 17/25 (68.0 %) in patients with stage I, II, and endometrial cancers, respectively]. Significant (P < 0.05) differences among groups were detected in patients’ age, body mass index and previous pelvic surgery, and in the distribution of stages and histotype of endometrial cancers. The Kaplan–Meier procedure showed that the cumulative probability of first recurrence (P = 0.089, 0.590 and 0.084 for stage I, II and III, respectively) and of death (P = 0.108, 0.567 and 0.372 for stage I, II and III, respectively) categorized by stages did not attain statistical significance by log-rank testing after correction for confounding factors.
Conclusions
The surgical and oncological outcomes of converted patients are no different from those of patients staged successfully with laparoscopy or with laparotomy. The conversion to laparotomy should be not considered per se a complication.