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International Ophthalmology

Erschienen in:

26.03.2018 | Original Paper

Corneal densitometry after accelerated corneal collagen cross-linking in progressive keratoconus

verfasst von: Myriam Böhm, Mehdi Shajari, Matthias Remy, Thomas Kohnen

Erschienen in: International Ophthalmology | Ausgabe 4/2019

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Abstract

Purpose

To analyze changes in corneal densitometry 3 months after accelerated corneal collagen cross-linking (CXL) measured with Scheimpflug tomography.

Methods

In this study we reviewed charts and anterior segment data of patients who had undergone accelerated pulsed epithelium-off CXL (30 mW/cm² for 4 min, 8 min total radiation time) for treatment of progressive keratoconus in the Department of Ophthalmology, Goethe University, Frankfurt, Germany. Visual, topographic, pachymetric and densitometric data were extracted before surgery and at the 3-month follow-up. Corneal densitometry measurements from different corneal layers and zones obtained using Scheimpflug tomography (Pentacam HR, Oculus).

Results

The study investigated 12 eyes of 12 patients. The anterior (120 μm) stromal layer within the 0.0 to 2.0 mm and 2.0 to 6.0 mm concentric zones showed a significant elevation of mean densitometry 3 months post-surgery (P = 0.045; P = 0.015) compared to baseline. A mean stromal demarcation line was apparent at a depth of 203.00 μm ± 13.53 (SD). After accelerated CXL, no change in mean corrected distance visual acuity (LogMAR) was observed but a thinning of the cornea measured by a significant reduction in central pachymetry (μm).

Conclusion

Accelerated CXL results in an increase in corneal densitometry, particularly in the anterior stromal layer within the two central concentric zones (0.0 to 2.0 mm and 2.0 to 6.0 mm) of the cornea at 3 months postoperatively. The changes in corneal densitometry of the anterior stromal layer did not correlate with postoperative visual acuity or central pachymetry.

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Titel: Corneal densitometry after accelerated corneal collagen cross-linking in progressive keratoconus
verfasst von: Myriam Böhm
Mehdi Shajari
Matthias Remy
Thomas Kohnen
Publikationsdatum: 26.03.2018
Verlag: Springer Netherlands
Erschienen in: International Ophthalmology / Ausgabe 4/2019
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-018-0876-4

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Corneal densitometry after accelerated corneal collagen cross-linking in progressive keratoconus

Abstract

Purpose

Methods

Results

Conclusion

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Abstract

Purpose

Methods

Results

Conclusion

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