Correction:
J Exp Clin Cancer Res
42, 76 (2023)
https://doi.org/10.1186/s13046-023-02649-6
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Following publication of the original article [1], an error was identified in Fig. 2, specifically:
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Fig. 2b - CL/F (mL/hr) needs to be corrected in CL/F (L/hr)
Furthermore, two Supplementary Materials should also be uploaded. The added Supplementary Materials are:
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Additional file 7: Supplementary Materials and Methods.
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Additional file 8: NEO-201 protocol.
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This modification does not affect the integrity of the results.
Fig. 2
Clinical Pharmacokinetics of NEO-201 A. NEO-201 serum concentrations averaged for each dose level and plotted over time. B. Noncompartmental analysis of first dose of NEO-201 including the mean estimates for relevant PK parameters during dense PK sampling following the first dose given on C1D1. *Data presented as arithmetic means (%CV) due to low numbers in each group. 1 Two patients had inaccurate estimates of C1D1 clearance and volume due to an overestimation of AUCinf. 2 One patient had insufficient terminal data to accurately estimate a half-life, thus clearance and volume too. 3 Four patients had inaccurate estimates of C1D1 clearance and volume due to an overestimation of AUCinf. 4 One patient had insufficient terminal data to accurately estimate a half-life, thus clearance and volume too. 5 Two patients had inaccurate estimates of C1D1 clearance and volume due to an overestimation of AUCinf. C. Individual NEO-201 serum concentration–time profiles of 1.0 mg/kg cohort. D-E. Individual NEO-201 serum concentration–time profiles of patients in 1.5 mg/kg cohort (D) and 2.0 mg/kg cohort (E). F-G. Differences in NEO-201 distribution volume by sex (F) and body size (G)
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