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01.10.2011 | Gynecologic Oncology

Correlation between breast arterial calcification detected on mammography and cerebral artery disease

verfasst von: Kook Jin Ahn, Young Joo Kim, Hang Joo Cho, Hyeon Woo Yim, Bong Joo Kang, Sung Hun Kim, Hyun Suk Kim, Ki Tae Kim, Jae Hee Lee, In Yong Whang

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 4/2011

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Abstract

Purpose

This study was carried out to determine the relationship between breast arterial calcification (BAC) and cerebral artery disease.

Materials and methods

We investigated the relationship between BAC on mammography and cerebral artery-origin T2-hyperintensity on brain MRI and which is associated with an increased risk for stroke. A total of 168 women, ages 40–78 years, who underwent both mammography and brain MRI, were enrolled in this study. BAC was counted as positive if it was found on more than one view a breast. The T2-hyperintensity was systemically defined and graded as follows: punctuate; patchy; and confluent white-matter hyperintensity (WMH); caps; bands; and irregular periventricular hyperintensity (PVH). Patchy and confluent WMH and irregular PVH were considered as positive findings for cerebral artery disease. We also obtained data regarding cardiovascular risk factors that might function as confounding factors. Statistical analysis was performed for association of the BAC and positive MRI findings.

Result

The presence of BAC showed a strong correlation with the positive MRI findings (Odds ratios, adjusted with statically significant cardiovascular factors of 6.86 for positive WMH and 9.04 for positive PVH, p < 0.05).

Conclusion

The mammographic finding of BAC, which may be a useful marker of women at higher risk for stroke, should receive more of clinicians’ attention and its presence should never be omitted from the report.

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Titel: Correlation between breast arterial calcification detected on mammography and cerebral artery disease
verfasst von: Kook Jin Ahn
Young Joo Kim
Hang Joo Cho
Hyeon Woo Yim
Bong Joo Kang
Sung Hun Kim
Hyun Suk Kim
Ki Tae Kim
Jae Hee Lee
In Yong Whang
Publikationsdatum: 01.10.2011
Verlag: Springer-Verlag
Erschienen in: Archives of Gynecology and Obstetrics / Ausgabe 4/2011
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-010-1742-4

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Correlation between breast arterial calcification detected on mammography and cerebral artery disease