Methods
Identification of domains and formulation of questions
Identification of experts to address questions
Topic | Leader | Experts |
---|---|---|
General introduction | Catalin Copaescu | Emina Letić, Silviu Daniel Preda, Alice Tsai, Ewelina Malanowska, Dusan Lesko, Wlodzimierz Majewski, Ludovica Baldari |
Hepatobiliary | Nicolò de Manzini | Luca Morelli, Andreas Shamiyeh, Gil Faria |
Bariatrics | Nicola Di Lorenzo | Francesco Maria Carrano, Piotr Mysliwiec, Gunnar Ahlberg |
Abdominal Wall | Stavros Antoniou | Elisa Cassinotti, Samir Delibegović, Lubomír Martinek |
Endocrine | Nicole Bouvy | Eugenia Yiannakopoulou, Marguerite Gorter-Stam, Hendrik Jaap Bonjer |
Upper GI | Beat P. Müller-Stich | George Hanna, Hans Fuchs, Miloš Bjelovic, Sheraz Markar, Philip Wai Yan, Chiu, Bang Wool Eom, Young-Woo Kim, Carmen Balagué Ponz, Marlies Schijven |
Lower GI | Michel Adamina | Luigi Boni, Thomas Carus, George Theodoropoulos, Antonello Forgione, Marco Milone, Wanda Luisa Rita Petz, Predag Andrejevic, Dejan Ignjatovic, Thanjakumar Arulampalam, Kenneth Campbell, Manish Chand, Mark Coleman, Christos Kontovounisios |
Technology & Research | Felix Nickel | Chen Sagiv, Fanny Ficuciello, Stefania Marconi, Pietro Mascagni, Kiyokazu Nakajima, Francisco Miguel Sánchez Margallo, Tim Horeman, George Mylonas, Pietro Valdastri |
Search methods and inclusion criteria
Formulation of questions and statements
Voting and data analysis
Results
Topics | Questions | Statement | 1st round % YES | 2nd round % YES |
---|---|---|---|---|
Introductory questions | 1. What are the appropriate measures to mitigate the risks of general anaesthesia in patients during COVID- 19 pandemic? | 1. All patients requiring surgery under general anaesthesia should be tested for COVID-19 by means of RT-PCR | 79% | |
Patient safety | a. Asymptomatic | 2. In case of PCR testing not available, imaging modalities such as CT or US lung scan can be used as a diagnostic tool before general anaesthesia | 90% | |
b. Symptomatic | 3. Surgical procedures should be carefully prioritized based on local resources, the regional control of the COVID-19 pandemic and the patients’ medical condition | 65% | 98% | |
4. When indicated, emergency surgery should be performed in all patients regardless of their COVID-19 status | 94% | |||
5. In COVID-19 positive patients, elective surgery for cancer and progressive diseases should be considered only after a negative PCR COVID-19 test | 80% | |||
6. In case of overutilization of hospital resources alternative/holding oncological therapies could be proposed to treat cancer in COVID-19 negative patients | 80% | |||
7. In case of symptomatic patients either suspected or confirmed COVID-19 positive, regional anaesthesia techniques should be considered when possible | 92% | |||
Introductory questions | 2. What is the optimal surgical approach during COVID- 19 pandemic in COVID + o symptomatic? | 94% | ||
Surgical approach | a. In elective vs. emergency cases | |||
b. in patients with moderately to severely compromised respiratory function (CPAP or endotracheal intubation) | ||||
c. in patients with mild to moderately compromised respiratory function (requiring mask oxygen therapy only) | ||||
d. in patients with normal respiratory function—Patients with either no symptoms or mild symptoms, without interstitial pneumonia or other pulmonary complications | ||||
3. What is the optimal surgical approach during COVID- 19 pandemic in COVID – or unknow but not suspected? | 8. General preference for minimal invasive surgery (MIS) according to guidelines should not change both in COVID-19 negative and positive patients as well as in elective and emergency settings, unless otherwise contraindicated, if adequate equipment and expertise are available | |||
a. In elective vs. emergency cases | 9. No a priori contraindication to a minimally invasive approach should be stated in COVID-19 positive patients with normal, mild or moderately compromised respiratory function | 92% | ||
Staff protection in OR | 4. What is the optimal personal protection equipment (PPE) that should be used during abdominal surgery in? | 10. The OR personnel should use standard PPE when operating on a tested COVID-19 negative patient | 80% | |
a. asymptomatic patients during COVID- 19 pandemic | ||||
b. symptomatic patients during COVID- 19 pandemic | ||||
c. positive patients during COVID- 19 pandemic | 11. When any aerosol generating procedure is indicated on a suspected or confirmed COVID-19 positive patient, symptomatic or asymptomatic, the OR staff should be reduced to minimum and should all wear high level of PPE, consisting of: medical hood, FFP2/FFP3 mask, eye protection/full-face shield, long sleeved fluid repellent gown / medical protecting coverall (ANSI/AAMI level 3–4), double disposable gloves, long waterproof leg cover | 94% | ||
d. in symptomatic or positive patients and Aerosol Generating Procedures (Laparoscopy/Endoscopy) during COVID- 19 pandemic | 12. It is of major importance that donning and doffing is performed under self-control or direct control of a colleague | 85% | ||
Specific measures in OR | 5. Which Specific Operative Risk Issues to consider during abdominal surgery in symptomatic or positive patients during COVID- 19 pandemic regarding? | 13. The risk of infection during laparoscopic surgery should be controlled by reducing gas leaks, the generation of smoke and by the application of surgical smoke evacuating systems | 98% | |
a. Reduce the risk of aerosol contamination during laparoscopy | 14. In order to control gas leaks, surgeons should: use low CO2 intraabdominal pressure, perform small incisions for the access ports, limit the exchange of surgical instruments and evacuate CO2 before any abdominal wall incision | 94% | ||
b. Minimizing Staff personnel | 15. In order to reduce the smoke generation during surgery in COVID-19 positive or suspected patients, the application of energy devices should be minimized, whereas ligatures/clips and/or stapling devices should be considered instead | 65% | 87% | |
c. Type of OR – COVID + OR/cleaning OR after surgery/negative pressure OR | 16. COVID-19 positive or suspected patients should be operated in a dedicated OR equipped with laminar air flow, negative pressure and downward evacuation system which should be cleaned by a dedicated specifically trained 24/7 team | 90% | ||
6. How should we change the design of the OR block to adapt to the risks of infections in the era of COVID- 19 pandemic? | 17. Disposable devices (instruments, trocars, etc.) should be preferred in COVID-19 positive or suspected patients | 76% | ||
a. Negative pressure | 18. All patients admitted should follow an initial screening triage, considering history of the patient, temperature, nasal swab and chest radiogram to detect COVID-19 status | 73% | ||
b. Distinct paths for COVID + and – patients | 19. Based on screening at admission, patients should be addressed to the COVID-19 positive, COVID-19 negative or suspected unit, as for local organization | 94% | ||
c. Design of equipment easily disinfected or disposable covers | 20. Distinct and separated paths should be created in any hospital for COVID-19 positive, COVID-19 negative or suspected patients | 98% | ||
Specific emergency operations in the immediate post-COVID-19 pandemic | ||||
Hepatobiliary | 7. What are specific measures in hepatobiliary disorders that should be considered during COVID-19 pandemic regarding? | 21. Antibiotics should be attempted as the only treatment for COVID positive/ suspected patients with severe cholecystitis and the response to treatment should be reassessed rapidly (24 h) | 83% | |
a. Role of a non-operative approach (antibiotics) in cholecystitis | 22. Transhepatic drainage should be proposed for compromised patients with severe cholecystitis, refractory to medical treatment at 24 h in COVID-19 positive patients | 78% | ||
b. Role of a non-operative approach (transhepatic drainage) in cholecystitis | 23. In COVID-19 positive patients with common bile duct and gall bladder stones a sequential approach (ERCP followed by Laparoscopy) should be preferred to a Laparo-Endoscopic Rendez-Vous (LERV) approach to reduce the risk of a prolonged anaesthesia | 84% | ||
c. Role of a Laparo-Endoscopic Rendez-Vous (LERV) approach (orotracheal intubation) in Jaundice for CBD obstruction | 24. Patients with obstructive common bile duct stones should be treated according to the severity of cholangitis regardless of the COVID-19 status, favouring medical treatment | 77% | ||
d. Role of non-surgical/ non-endoscopic approach (only ERCP) in Jaundiced patients | 25. Patients with a non-calcular obstructive jaundice should be referred to tertiary centres in order to choose the best treatment (PTBD-ERCP-upfront surgery) | 84% | ||
26. Upfront surgery should not be offered to COVID-19 positive patients with non-calcular obstructive jaundice | 80% | |||
27. Cholecystectomy should be indicated in severe cholecystitis that is not responsive to conservative or interventional treatment, even COVID-19 positive patients | 89% | |||
Abdominal wall hernias | 8. What are specific measures in abdominal wall hernia surgery that should be considered during COVID-19 pandemic regarding? | 28. Laparoscopic approach to incarcerated ventral and inguinal hernia may be safe in COVID-19 positive patients if laparoscopy is not otherwise contraindicated | 80% | |
a. Laparoscopy in incarcerated ventral/incisional hernia | ||||
b. Laparoscopy in incarcerated inguinal hernia | ||||
c. Role of meshes in emergency | 29. In COVID-19 unknown patients, delaying surgery of an incarcerated ventral and inguinal hernia to obtain test results may not be justified | 89% | ||
d. Role of techniques that might increase intraabdominal pressure | 30. The use of mesh for hernia repair may not increase the risk of complications in COVID-19 positive patients | 89% | ||
e. Surgical approach if a bowel resection is needed | 31. Laparoscopic approach to incarcerated hernia requiring bowel resection may be safe for COVID-19 positive patients if not otherwise contraindicated | 80% | ||
Upper GI | 9. What is the role for flexible endoscopy mitigating the risk of surgery during COVID-19 pandemic in the following situations? | 32. Flexible endoscopic therapy should be the first attempt to treat upper GI bleeding even in patients affected by COVID-19 | 93% | |
a. Acute gastric volvulus | ||||
b. Obstructing gastric cancer | ||||
c. Obstructing esophageal cancer | ||||
d. Esophageal perforation | ||||
e. Surgical leaks | ||||
f. Bleeding | 33. COVID-19 positive patients with an obstructing esophageal or gastric cancer should be treated first by endoscopic stenting if possible, in order to delay surgery until conditions are more favourable to operate | 81% | ||
10. What is the role for surgical endoscopy during COVID-19 pandemic in the following situations? | 34. COVID-19 positive patients with an immediate presentation of benign esophageal perforation (of less than 24 h) should be treated first by flexible endoscopy means, while those perforated present after 24 h should undergo immediate surgery | 83% | ||
a. Esophageal perforation | 35. In patients suffering from an upper GI anastomotic leak, initial endoscopic therapy should be attempted regardless the COVID-19 status | 88% | ||
b. Gastroduodenal perforation | 36. Emergency surgery should be recommended after failure of conservative/endoscopic management in symptomatic upper GI perforation or leak in COVID-19 positive patients | 98% | ||
c. Bleeding | 37. Laparoscopy should be the preferred approach in patients with perforated gastroduodenal ulcer if not otherwise contraindicated in COVID-19 positive patients | 84% | ||
Lower GI | 11. What is the role for flexible endoscopy mitigating the risk of surgery during COVID-19 pandemic in the following situations? | 38. Endoscopic stenting for obstructing colorectal carcinoma should be considered for palliation in malignant obstruction regardless of the COVID-19 status | 67% | 87% |
a. Stenting for obstructing colorectal carcinoma | ||||
b. Decompression of acute sigmoid volvulus | ||||
c. Management of acute perforation | 39. Endoscopic decompression should be the first line of treatment of uncomplicated sigmoid volvulus, regardless the COVID-19 status | 91% | ||
d. Management of anastomotic leaks | 40. In patients suffering from a leak of a low rectal anastomosis, all endoscopic means which proved effective should be attempted regardless the COVID-19 status | 81% | ||
12. What is the role for laparoscopy during COVID-19 pandemic in the following situations? | 41. Emergency surgery should be recommended after failure of conservative/endoscopic management in symptomatic lower GI perforation or leak in COVID-19 positive patients | 93% | ||
a. Acute diverticulitis (lavage/HP/Primary Resection anastomosis with stoma) | 42. The indication for laparoscopic lavage for Diverticular Disease can be considered in COVID-19 positive patients when local expertise and protective measures are available | 65% | 87% | |
b. Small bowel obstruction | 43. Primary resection with or without anastomosis can be considered in COVID-19 positive patients with acute diverticulitis, providing that this is performed by an experienced surgeon | 86% | ||
c. Appendicitis (with/without abscess/abdominal collection) | 44. Percutaneous drainage and/or targeted defunctioning stoma can be considered in unstable COVID-19 positive patients with acute diverticulitis | 88% | ||
13. Should damage control surgery be performed in COVID + / suspected COVID-19 patients? | 45. Laparoscopic approach should be considered in COVID-19 positive patients with virgin abdomen and acute small bowel obstruction that is likely due to a single adhesion band, which is suspected at CT scan | 91% | ||
a. In Upper GI | 46. Non-surgical approaches such as percutaneous drainage with antibiotic treatment should be considered as the first line of treatment of acute appendicitis with peri-appendicular abscess in COVID-19 positive patients | 81%% | ||
b. In Lower GI | 47. In case of failed non-surgical approach for acute appendicitis in COVID-19 positive patients, laparoscopic surgery should be considered | 91% | ||
c. In Pancreas surgery | 48. The principles of damage control surgery with adherence to optimal seal of temporary abdominal closure should remain unchanged in COVID-19 positive/suspected patients | 98% | ||
Specific elective operations in the immediate post-COVID-19 pandemic | ||||
Hepatobiliary | 14. What indications for laparoscopic surgery in hepatobiliary disorders should be considered during COVID-19 pandemic regarding? | 49. Elective cholecystectomy in patients COVID-19 negative may be performed if hospital setting allows a safe pathway for COVID-19 negative patients and local resources are sufficient | 98% | |
a. Cholelithiasis/choledocholithiasis and adenomyoma | 50. Elective cholecystectomy in patients COVID-19 positive should be delayed until the post-pandemic period | 81% | ||
b. Hepatic cancer | 51. Elective liver resection for primary or secondary cancer in COVID-19 negative patients should not be delayed | 86% | ||
c. Liver metastases | 52. Elective liver resection for primary or secondary cancer in COVID-19 positive patients should be delayed until patients fully recover from COVID. Jaundice or infection should be first treated with PTBD or ERCP as a bridge therapy | 93% | ||
d. Pancreatic cancer | 53. Patients affected by unproven pancreatic lesion could be observed and intervention can be delayed until the post-pandemic period | 69% | 73% | |
e. Other indications | 54. Elective pancreatic resection for cancer in COVID-19 negative patients should not be delayed | 90% | ||
55. Elective liver resection for cancer in COVID-19 positive patients should be delayed until patients fully recover from COVID. Jaundice or infection should be first treated with PTBD or ERCP as a bridge therapy | 90% | |||
Bariatrics | 15. What is the role for flexible endoscopy mitigating the risk of surgery during COVID-19 pandemic in bariatrics? | 56. In order to mitigate the risk of surgery during the recovery plan after the COVID-19 pandemic, all endoscopic techniques for morbid obesity should be preferred as bridge to surgery | 70% | |
a. Should bariatric procedure be postponed? | ||||
b. Role of bridging procedures (balloons and others) | ||||
c. Treatment of complications of bariatric surgery | 57. Intragastric Balloon placement can be a valid alternative to endoscopic sleeve gastroplasty in order to reduce procedure times and resources usage during the COVID pandemic | 68% | 76% | |
16. Is there a different timing for surgery during COVID-19 pandemic in bariatrics? | 58. In patients experiencing a complication (bleeding or leak) following a bariatric procedure, all endoscopic means which proved effective should be put in place regardless of COVID-19 status | 98% | ||
a. Should bariatric procedure be postponed? | 59. During the recovery plan after the COVID-19 pandemic, bariatric surgery should not be postponed further, nor the indications limited in areas with a low incidence of SARS-CoV-2 infections | 77% | ||
b. When should a redo procedure be performed? | 60. In case local regulatory authorities impose a reduction of bariatric weekly case load, more complex metabolic patients should be prioritized | 98% | ||
Abdominal wall | 17. What indications to surgery and what anaesthesia in abdominal wall disorders should be considered during COVID-19 pandemic regarding? | 61. Elective laparoscopic treatment for ventral and inguinal hernias in COVID-19 negative asymptomatic or poorly symptomatic patients may need to be postponed | 90% | |
a. Ventral hernias | ||||
b. Inguinal hernias | ||||
c. Role of watch&wait policy | 62. A watchful waiting management may be safe in asymptomatic patients and patients with abdominal wall hernia and minimal symptoms that do not substantially affect quality of life | 90% | ||
d. Should Spinal anaesthesia always be preferred? what will be the indications? | 63. Both general and spinal anaesthesia for hernia repair should be considered safe in COVID-19 negative patients. The choice should follow local guidelines and patient’s preference | 95% | ||
Endocrine | 18. What indications to laparoscopic surgery in endocrine disorders should be considered during COVID-19 pandemic regarding? | 64. In the recovery plan after COVID-19 Pandemic indications to laparoscopic surgery and priorities in endocrine disorders should not change | 95% | |
a. Functional adrenal tumour | 65. Elective adrenal resection for primary or secondary cancer in COVID-19 negative patients should not be delayed | 98% | ||
b. Adrenal cancer | 66. Elective adrenal resection for primary or secondary cancer in COVID-19 positive patients should be delayed until patients fully recover from COVID | 93% | ||
c. Adrenal metastases | 67. Elective adrenal resection for functional tumours (pheochromocytoma and severe Cushing) in COVID-19 negative patients should not be delayed | 93% | ||
d. Thyroid goiter | 68. Elective adrenal resection for functional tumours (pheochromocytoma and severe Cushing) in COVID-19 positive patients should be delayed until patients fully recover from COVID | 93% | ||
e. Thyroid cancer (or suspected) | 69. Elective surgery for thyroid nodules Bethesda V and TIRADS 5 or higher in COVID-19 negative patients should not be delayed | 95% | ||
f. P-Nets | 70. Elective surgery for thyroid nodules Bethesda V and TIRADS 5 or higher in COVID-19 positive patients should be delayed until patients fully recover from COVID | 95% | ||
71. Patients affected by thyroid goiter severely symptomatic for dyspnea should not have surgery delayed regardless of the COVID status | 93% | |||
Upper GI | 19. When and how should surgery for Upper GI disorders be postponed during COVID-19 pandemic? | 72. In COVID-19 positive patients who suffer from early esophageal or gastric cancer surgery should be delayed and neoadjuvant treatment should be considered even if not normally indicated | 71% | |
a. Should we extend the indications for neoadjuvant treatment to early esophageal cancer? | ||||
b. Should we extend the duration (cycles) of neoadjuvant treatment to esophageal cancer? | ||||
20. What is the role for flexible endoscopy mitigating the risk of surgery during COVID-19 pandemic in upper GI functional diseases? | ||||
a. Achalasia (including POEM)? | ||||
b. Anti-reflux procedures (Esophyx/MUSE)? | ||||
21. Does surgical endoscopy still have a role during COVID-19 pandemic in the treatment of the following diseases? | ||||
a. Esophageal cancer | 73. Patients affected by benign Upper GI functional disorders such as achalasia and GERD should be considered for flexible endoscopic intervention if not responding to medical treatment, after the COVID pandemic | 59% | 93% | |
b. Gastric cancer (total / subtotal gastrectomy) | 74. Patients affected by neoplastic disease of the upper GI for whom surgery is indicated, should be considered for an MIS approach, if not otherwise contraindicated, after the COVID pandemic | 81% | ||
c. Hiatal hernia & reflux disease | 75. In COVID-19 positive patients with a surgical indication for GERD, hiatal hernia or achalasia surgery should be delayed | 88% | ||
Lower GI | 22. When and how should surgery for Lower GI disorders be postponed during COVID-19 pandemic? | 76. Prioritization of elective surgery for benign colorectal pathologies should be made taking into account the patient and disease characteristics, local COVID-19 burden and institutional and staff resources | 95% | |
a. Should we extend the indications for neoadjuvant treatment to early rectal cancer? | ||||
b. Should be opt for total neoadjuvant radiochemotherapy including upfront chemotherapy, for rectal cancer? | ||||
c. How much should we wait after CRT? | ||||
d. Role of watch&wait policy for rectal cancer with complete response | ||||
e. Should we propose total neoadjuvant chemotherapy for colon cancer? | ||||
f. Should we extend the indications for “liver first” and postpone rectal resection? | ||||
23. What is the risk in performing colorectal anastomoses during COVID-19 pandemic? | 77. Neoadjuvant therapy could be considered in early rectal cancer in order to postpone surgery after the COVID pandemic, within registered studies | 66% | 82% | |
a. Should we avoid anastomosis (HP?) | 78. Patients with rectal cancer should not be offered chemoradiotherapy including upfront chemotherapy as a sole treatment outside clinical trials | 83% | ||
b. Should always protect anastomosis with stoma? | 79. Surgery for rectal cancer in patients COVID-19 positive should be delayed beyond the standard 12 weeks following neoadjuvant chemoradiotherapy | 78% | ||
24. What is the role for transanal surgery during COVID-19 pandemic? | 80. A watch and wait policy for neoadjuvant treated rectal cancer should be proposed only in the setting of clinical trials and/or when surgery is contraindicated | 82% | ||
a. Cost/effectiveness of transanal surgery compared to flexible endoscopy in terms of risk for patient and operators? | 81. During the COVID-19 pandemic and the recovery plan, neoadjuvant chemotherapy can be proposed to patients affected by stage II and III colon cancers | 78% | ||
b. Role of TaTME and ultra-low anastomosis? | 82. A liver first approach in locally advanced rectal cancer and synchronous liver metastases cannot be recommended solely based on the pandemic situation | 95% | ||
25. What is the optimal surgical approach during COVID- 19 pandemic for? | 83. In COVID-19 negative patients undergoing elective colorectal resection, anastomosis should be considered if not otherwise contraindicated | 98% | ||
a. Colon cancer | 84. Stoma formation should be preferred to an anastomosis in all patients medically unfit or COVID-19 positive | 83% | ||
b. Symptomatic chronic diverticulitis | 85. Alternative strategies to TEMS/TAMIS for low rectal lesions, such as endoscopic mucosal resection and endoscopic submucosal dissection, should be considered in COVID-19 positive | 72% | ||
c. Inflammatory Bowel Disease | 86. Overall, taTME and ultra-low anastomosis are procedures at higher risk of complications and should only be performed selectively in expert centres to minimize resource consumption during the pandemic | 93% | ||
d. Rectal prolapse (laparoscopy vs transanal approach) | 87. MIS approach should be considered to electively treat colon cancer as well as benign conditions such as inflammatory bowel diseases and recurrent diverticulitis, due to its well proved benefits of reducing morbidity, during the pandemic | 88% | ||
New technologies demanded | ||||
Technology | 26. Which specific Operative Risk Issues to consider in case of abdominal surgery in symptomatic or positive patients during COVID- 19 pandemic? | 88. Research activity on digital technology and robotics should be encouraged to focus on reducing personnel in wards, intensive care unit and OR | 98% | |
a. Use of active/passive smoke evacuator | ||||
b. Use of reusable/disposable trocars | ||||
c. Use specific type of reusable trocars (Ballon at the tip, bladeless, etc.…) | ||||
d. Use of reusable/disposable instruments | ||||
e. Use of advanced dissectors (Ultrasonic, Radiofrequency,…) vs standard mono & bipolar | ||||
f. Use of cold knifes, scissors and ligatures/sutures | ||||
27. Is it time to use robotics technology to reduce the employment of human beings and/or to keep social distance for… | ||||
a. OR surgical instrumentation | ||||
b. Scrub nurse and OR personnel | ||||
c. Ward personnel | ||||
d. Other… | ||||
28. In the era of attention to climate changes and pollution, how to deal with technology solutions to limit quantity of waste dispersal? | ||||
a. How to recycle PPE? | ||||
b. How to recycle the increasing disposable material? | ||||
c. How to be sure that reprocessing is effective? | ||||
29. While the COVID-19 pandemic is severely affecting educational programs in surgery, can we envision technology solutions for training, such as …? | ||||
a. Hands on courses on 3D printed organs / districts | ||||
b. Virtual Reality simulators | ||||
c. Consultation of selected Videolibrary | ||||
d. Attending of Online Congresses | ||||
e. Extensive webinar activity for education | 89. Practical technological solutions including sustainable materials and steam sterilization for PPE should be investigated in order to minimize production of waste | 96% | ||
f. Real time education via telesurgery for open and laparoscopic operations | 90. Innovative solutions for training such as video-based education in combination with box trainers should be promoted to mitigate the restrictions of face-to-face teaching | 96% | ||
Research | 30. Should clinical research restart? | 91. Non-COVID clinical research should restart as soon as possible in line with safety recommendations and procedures | 98% | |
92. Particular attention should be payed to research targeting preventive and mitigation strategies of aerosol contamination in the OR and safety of MIS | 96% |