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Erschienen in: European Radiology 7/2004

01.07.2004 | Hepatobiliary-Pancreas

Cross-sectional imaging of biliary tumors: current clinical status and future developments

verfasst von: Christoph J. Zech, Stefan O. Schoenberg, Maximilian Reiser, Thomas Helmberger

Erschienen in: European Radiology | Ausgabe 7/2004

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Abstract

Extrahepatic cholangiocarcinoma, including hilar cholangiocarcinoma, is a relatively rare diagnosis. However, it frequently has been associated with major problems in diagnostics and clinical management from its first comprehensive description by Klatskin up until today. In this article, cholangiocarcinoma, representing the most common biliary tumor, as well as the differential diagnoses of benign and malignant biliary obstruction, will be discussed. The latest improvements of cross-sectional imaging modalities (sonography, CT, MRI and PET) and their diagnostic values for detection and staging will be displayed. A practical imaging-based diagnostic approach to obstructive biliary disease will be proposed.
Literatur
1.
Zurück zum Zitat Klatskin G (1965) Adenocarcinoma of the hepatic duct at its bifurcation within the porta hepatis. An unusual tumor with distinctive clinical and pathological. Am J Med 38:241–256 Klatskin G (1965) Adenocarcinoma of the hepatic duct at its bifurcation within the porta hepatis. An unusual tumor with distinctive clinical and pathological. Am J Med 38:241–256
2.
Zurück zum Zitat Greenlee RT, Murray T, Bolden S, Wingo PA (2000) Cancer statistics (2000). CA Cancer J Clin 50:7–33PubMed Greenlee RT, Murray T, Bolden S, Wingo PA (2000) Cancer statistics (2000). CA Cancer J Clin 50:7–33PubMed
4.
Zurück zum Zitat Lim JH, Kim MH, Kim TK et al (2003) Papillary neoplasms of the bile duct that mimic biliary stone disease. Radiographics 23:447–455PubMed Lim JH, Kim MH, Kim TK et al (2003) Papillary neoplasms of the bile duct that mimic biliary stone disease. Radiographics 23:447–455PubMed
5.
Zurück zum Zitat Levy AD, Murakata LA, Abbott RM, Rohrmann CA Jr (2002) From the archives of the AFIP. Benign tumors and tumorlike lesions of the gallbladder and extrahepatic bile ducts: radiologic-pathologic correlation. Radiographics 22:387–413PubMed Levy AD, Murakata LA, Abbott RM, Rohrmann CA Jr (2002) From the archives of the AFIP. Benign tumors and tumorlike lesions of the gallbladder and extrahepatic bile ducts: radiologic-pathologic correlation. Radiographics 22:387–413PubMed
6.
Zurück zum Zitat Knoefel WT, Prenzel KL, Peiper M et al (2003) Klatskin tumors and Klatskin mimicking lesions of the biliary tree. Eur J Surg Oncol 29:658–661CrossRefPubMed Knoefel WT, Prenzel KL, Peiper M et al (2003) Klatskin tumors and Klatskin mimicking lesions of the biliary tree. Eur J Surg Oncol 29:658–661CrossRefPubMed
7.
Zurück zum Zitat Inaba K, Suzuki S, Yokoi Y et al (2003) Hepatic inflammatory pseudotumor mimicking intrahepatic cholangiocarcinoma: report of a case. Surg Today 33:714–717CrossRefPubMed Inaba K, Suzuki S, Yokoi Y et al (2003) Hepatic inflammatory pseudotumor mimicking intrahepatic cholangiocarcinoma: report of a case. Surg Today 33:714–717CrossRefPubMed
8.
Zurück zum Zitat Bismuth H, Corlette MB (1975) Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver. Surg Gynecol Obstet 140:170–178PubMed Bismuth H, Corlette MB (1975) Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver. Surg Gynecol Obstet 140:170–178PubMed
9.
Zurück zum Zitat Han JK, Choi BI, Kim AY et al (2002) Cholangiocarcinoma: pictorial essay of CT and cholangiographic findings. Radiographics 22:173–187PubMed Han JK, Choi BI, Kim AY et al (2002) Cholangiocarcinoma: pictorial essay of CT and cholangiographic findings. Radiographics 22:173–187PubMed
10.
Zurück zum Zitat Braga HJ, Imam K, Bluemke DA (2001) MR imaging of intrahepatic cholangiocarcinoma: use of ferumoxides for lesion localization and extension. Am J Roentgenol 177:111–114 Braga HJ, Imam K, Bluemke DA (2001) MR imaging of intrahepatic cholangiocarcinoma: use of ferumoxides for lesion localization and extension. Am J Roentgenol 177:111–114
11.
Zurück zum Zitat Maetani Y, Itoh K, Watanabe C et al (2001) MR imaging of intrahepatic cholangiocarcinoma with pathologic correlation. Am J Roentgenol 176:1499–1507 Maetani Y, Itoh K, Watanabe C et al (2001) MR imaging of intrahepatic cholangiocarcinoma with pathologic correlation. Am J Roentgenol 176:1499–1507
12.
Zurück zum Zitat Kim JH, Kim MJ, Chung JJ, Lee WJ, Yoo HS, Lee JT (2002) Differential diagnosis of periampullary carcinomas at MR imaging. Radiographics 22:1335–1352PubMed Kim JH, Kim MJ, Chung JJ, Lee WJ, Yoo HS, Lee JT (2002) Differential diagnosis of periampullary carcinomas at MR imaging. Radiographics 22:1335–1352PubMed
13.
Zurück zum Zitat Tannapfel A, Wittekind C (2001) Anatomy and pathology of intrahepatic and extrahepatic bile duct tumors. Pathologe 22:114–123CrossRefPubMed Tannapfel A, Wittekind C (2001) Anatomy and pathology of intrahepatic and extrahepatic bile duct tumors. Pathologe 22:114–123CrossRefPubMed
14.
Zurück zum Zitat Manfredi R, Masselli G, Maresca G, Brizi MG, Vecchioli A, Marano P (2003) MR imaging and MRCP of hilar cholangiocarcinoma. Abdom Imaging 28:319–325CrossRefPubMed Manfredi R, Masselli G, Maresca G, Brizi MG, Vecchioli A, Marano P (2003) MR imaging and MRCP of hilar cholangiocarcinoma. Abdom Imaging 28:319–325CrossRefPubMed
15.
Zurück zum Zitat Cha JH, Han JK, Kim TK et al (2000) Preoperative evaluation of Klatskin tumor: accuracy of spiral CT in determining vascular invasion as a sign of unresectability. Abdom Imaging 25:500–507CrossRefPubMed Cha JH, Han JK, Kim TK et al (2000) Preoperative evaluation of Klatskin tumor: accuracy of spiral CT in determining vascular invasion as a sign of unresectability. Abdom Imaging 25:500–507CrossRefPubMed
16.
Zurück zum Zitat Lygidakis NJ, Sgourakis GJ, Dedemadi GV, Vlachos L, Safioleas M (2001) Long-term results following resectional surgery for Klatskin tumors. A twenty-year personal experience. Hepatogastroenterology 48:95–101 Lygidakis NJ, Sgourakis GJ, Dedemadi GV, Vlachos L, Safioleas M (2001) Long-term results following resectional surgery for Klatskin tumors. A twenty-year personal experience. Hepatogastroenterology 48:95–101
17.
Zurück zum Zitat Bathe OF, Pacheco JT, Ossi PB et al (2001) Management of hilar bile duct carcinoma. Hepatogastroenterology 48:1289–1294 Bathe OF, Pacheco JT, Ossi PB et al (2001) Management of hilar bile duct carcinoma. Hepatogastroenterology 48:1289–1294
18.
Zurück zum Zitat Khan SA, Davidson BR, Goldin R et al (2002) Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document. Gut 51[Suppl 6]:VI 1–9 Khan SA, Davidson BR, Goldin R et al (2002) Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document. Gut 51[Suppl 6]:VI 1–9
19.
Zurück zum Zitat Sobin LH, Wittekind C (2002) TNM classification of malignant tumours, 6th edn. Wiley, New York Sobin LH, Wittekind C (2002) TNM classification of malignant tumours, 6th edn. Wiley, New York
20.
Zurück zum Zitat Weber SM, Jarnagin WR, Klimstra D, DeMatteo RP, Fong Y, Blumgart LH (2001) Intrahepatic cholangiocarcinoma: resectability, recurrence pattern, and outcomes. J Am Coll Surg 193:384–391CrossRefPubMed Weber SM, Jarnagin WR, Klimstra D, DeMatteo RP, Fong Y, Blumgart LH (2001) Intrahepatic cholangiocarcinoma: resectability, recurrence pattern, and outcomes. J Am Coll Surg 193:384–391CrossRefPubMed
21.
Zurück zum Zitat Courbiere M, Pilleul F, Henry L, Ponchon T, Touzet S, Valette PJ (2003) Value of magnetic resonance cholangiography in benign and malignant biliary stenosis: comparative study with direct cholangiography. J Comput Assist Tomogr 27:315–320 Courbiere M, Pilleul F, Henry L, Ponchon T, Touzet S, Valette PJ (2003) Value of magnetic resonance cholangiography in benign and malignant biliary stenosis: comparative study with direct cholangiography. J Comput Assist Tomogr 27:315–320
22.
Zurück zum Zitat Yeh TS, Jan YY, Tseng JH et al (2000) Malignant perihilar biliary obstruction: magnetic resonance cholangiopancreatographic findings. Am J Gastroenterol 95:432–440PubMed Yeh TS, Jan YY, Tseng JH et al (2000) Malignant perihilar biliary obstruction: magnetic resonance cholangiopancreatographic findings. Am J Gastroenterol 95:432–440PubMed
23.
Zurück zum Zitat Moon SG, Han JK, Kim (2003) Biliary obstruction in metastatic disease: thin-section helical CT findings. Abdom Imaging 28:45–52CrossRefPubMed Moon SG, Han JK, Kim (2003) Biliary obstruction in metastatic disease: thin-section helical CT findings. Abdom Imaging 28:45–52CrossRefPubMed
24.
Zurück zum Zitat Mulholland MW, Yahanda A, Yeo CJ (2001) Multidisciplinary management of perihilar bile duct cancer. J Am Coll Surg 193:440–447CrossRefPubMed Mulholland MW, Yahanda A, Yeo CJ (2001) Multidisciplinary management of perihilar bile duct cancer. J Am Coll Surg 193:440–447CrossRefPubMed
25.
Zurück zum Zitat Masci E, Toti G, Mariani A et al (2001) Complications of diagnostic and therapeutic ERCP: a prospective multicenter study. Am J Gastroenterol 96:417–423PubMed Masci E, Toti G, Mariani A et al (2001) Complications of diagnostic and therapeutic ERCP: a prospective multicenter study. Am J Gastroenterol 96:417–423PubMed
26.
Zurück zum Zitat Rosch T, Meining A, Fruhmorgen S et al (2002) A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT, and EUS in biliary strictures. Gastrointest Endosc 55:870–876CrossRefPubMed Rosch T, Meining A, Fruhmorgen S et al (2002) A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT, and EUS in biliary strictures. Gastrointest Endosc 55:870–876CrossRefPubMed
27.
Zurück zum Zitat Burtin P, Palazzo L, Canard JM, Person B, Oberti F, Boyer J (1997) Diagnostic strategies for extrahepatic cholestasis of indefinite origin: endoscopic ultrasonography or retrograde cholangiography? Results of a prospective study. Endoscopy 29:349–355PubMed Burtin P, Palazzo L, Canard JM, Person B, Oberti F, Boyer J (1997) Diagnostic strategies for extrahepatic cholestasis of indefinite origin: endoscopic ultrasonography or retrograde cholangiography? Results of a prospective study. Endoscopy 29:349–355PubMed
28.
Zurück zum Zitat Ponchon T (2000) Diagnostic endoscopic retrograde cholangiopancreatography. Endoscopy 32:200–208CrossRefPubMed Ponchon T (2000) Diagnostic endoscopic retrograde cholangiopancreatography. Endoscopy 32:200–208CrossRefPubMed
29.
Zurück zum Zitat Bloom CM, Langer B, Wilson SR (1999) Role of US in the detection, characterization, and staging of cholangiocarcinoma. Radiographics 19:1199–1218PubMed Bloom CM, Langer B, Wilson SR (1999) Role of US in the detection, characterization, and staging of cholangiocarcinoma. Radiographics 19:1199–1218PubMed
30.
Zurück zum Zitat Itoh S, Ikeda M, Ota T, Satake H, Takai K, Ishigaki T (2003) Assessment of the pancreatic and intrapancreatic bile ducts using 0.5-mm collimation and multiplanar reformatted images in multislice CT. Eur Radiol 13:277–285PubMed Itoh S, Ikeda M, Ota T, Satake H, Takai K, Ishigaki T (2003) Assessment of the pancreatic and intrapancreatic bile ducts using 0.5-mm collimation and multiplanar reformatted images in multislice CT. Eur Radiol 13:277–285PubMed
31.
Zurück zum Zitat Fletcher JG, Wiersema MJ, Farrell MA et al (2003) Pancreatic malignancy: value of arterial, pancreatic, and hepatic phase imaging with multi-detector row CT. Radiology 229:81–90PubMed Fletcher JG, Wiersema MJ, Farrell MA et al (2003) Pancreatic malignancy: value of arterial, pancreatic, and hepatic phase imaging with multi-detector row CT. Radiology 229:81–90PubMed
32.
Zurück zum Zitat Tillich M, Mischinger HJ, Preisegger KH, Rabl H, Szolar DH (1998) Multiphasic helical CT in diagnosis and staging of hilar cholangiocarcinoma. Am J Roentgenol 171:651–658PubMed Tillich M, Mischinger HJ, Preisegger KH, Rabl H, Szolar DH (1998) Multiphasic helical CT in diagnosis and staging of hilar cholangiocarcinoma. Am J Roentgenol 171:651–658PubMed
33.
Zurück zum Zitat Nesbit GM, Johnson CD, James EM, MacCarty RL, Nagorney DM, Bender CE (1988) Cholangiocarcinoma:diagnosis and evaluation of resectability by CT and sonography as procedures complementary to cholangiography. Am J Roentgenol 151:933–938 Nesbit GM, Johnson CD, James EM, MacCarty RL, Nagorney DM, Bender CE (1988) Cholangiocarcinoma:diagnosis and evaluation of resectability by CT and sonography as procedures complementary to cholangiography. Am J Roentgenol 151:933–938
34.
Zurück zum Zitat Gulliver DJ, Baker ME, Cheng CA, Meyers WC, Pappas TN (1992) Malignant biliary obstruction: efficacy of thin-section dynamic CT in determining resectability. Am J Roentgenol 159:503–507 Gulliver DJ, Baker ME, Cheng CA, Meyers WC, Pappas TN (1992) Malignant biliary obstruction: efficacy of thin-section dynamic CT in determining resectability. Am J Roentgenol 159:503–507
35.
Zurück zum Zitat Feydy A, Vilgrain V, Denys A et al (1999) Helical CT assessment in hilar cholangiocarcinoma: correlation with surgical and pathologic findings. Am J Roentgenol 172:73–77 Feydy A, Vilgrain V, Denys A et al (1999) Helical CT assessment in hilar cholangiocarcinoma: correlation with surgical and pathologic findings. Am J Roentgenol 172:73–77
36.
Zurück zum Zitat Campbell WL, Peterson MS, Federle MP et al (2001) Using CT and cholangiography to diagnose biliary tract carcinoma complicating primary sclerosing cholangitis. Am J Roentgenol 177:1095–1100 Campbell WL, Peterson MS, Federle MP et al (2001) Using CT and cholangiography to diagnose biliary tract carcinoma complicating primary sclerosing cholangitis. Am J Roentgenol 177:1095–1100
37.
Zurück zum Zitat Ochotorena IJ, Kiyosue H, Hori Y, Yokoyama S, Yoshida T, Mori H (2000) The local spread of lower bile duct cancer: evaluation by thin-section helical CT. Eur Radiol 10:1106–1113CrossRefPubMed Ochotorena IJ, Kiyosue H, Hori Y, Yokoyama S, Yoshida T, Mori H (2000) The local spread of lower bile duct cancer: evaluation by thin-section helical CT. Eur Radiol 10:1106–1113CrossRefPubMed
38.
Zurück zum Zitat Van Beers BE, Lacrosse M, Trigaux JP, de Canniere L, De Ronde T, Pringot J (1994) Noninvasive imaging of the biliary tree before or after laparoscopic cholecystectomy: use of three-dimensional spiral CT cholangiography. Am J Roentgenol 162:1331–1335 Van Beers BE, Lacrosse M, Trigaux JP, de Canniere L, De Ronde T, Pringot J (1994) Noninvasive imaging of the biliary tree before or after laparoscopic cholecystectomy: use of three-dimensional spiral CT cholangiography. Am J Roentgenol 162:1331–1335
39.
Zurück zum Zitat Greenberg M, Greenberg BM, Rubin JM, Greenberg IM (1982) Computed-tomographic cholangiography: a new technique for evaluating the head of the pancreas and distal biliary tree. Radiology 144:363–368PubMed Greenberg M, Greenberg BM, Rubin JM, Greenberg IM (1982) Computed-tomographic cholangiography: a new technique for evaluating the head of the pancreas and distal biliary tree. Radiology 144:363–368PubMed
40.
Zurück zum Zitat Zandrino F, Benzi L, Ferretti ML, Ferrando R, Reggiani G, Musante F (2002) Multislice CT cholangiography without biliary contrast agent: technique and initial clinical results in the assessment of patients with biliary obstruction. Eur Radiol 12:1155–1161CrossRefPubMed Zandrino F, Benzi L, Ferretti ML, Ferrando R, Reggiani G, Musante F (2002) Multislice CT cholangiography without biliary contrast agent: technique and initial clinical results in the assessment of patients with biliary obstruction. Eur Radiol 12:1155–1161CrossRefPubMed
41.
Zurück zum Zitat Maniatis P, Triantopoulou C, Sofianou E et al (2003) Virtual CT cholangiography in patients with choledocholithiasis. Abdom Imaging 28:536–544CrossRefPubMed Maniatis P, Triantopoulou C, Sofianou E et al (2003) Virtual CT cholangiography in patients with choledocholithiasis. Abdom Imaging 28:536–544CrossRefPubMed
42.
Zurück zum Zitat Caoili EM, Paulson EK, Heyneman LE, Branch MS, Eubanks WS, Nelson RC (2000) Helical CT cholangiography with three-dimensional volume rendering using an oral biliary contrast agent: feasibility of a novel technique. Am J Roentgenol 174:487–492 Caoili EM, Paulson EK, Heyneman LE, Branch MS, Eubanks WS, Nelson RC (2000) Helical CT cholangiography with three-dimensional volume rendering using an oral biliary contrast agent: feasibility of a novel technique. Am J Roentgenol 174:487–492
43.
Zurück zum Zitat Fulcher AS, Turner MA (1997) HASTE MR cholangiography in the evaluation of hilar cholangiocarcinoma. Am J Roentgenol 169:1501–1505 Fulcher AS, Turner MA (1997) HASTE MR cholangiography in the evaluation of hilar cholangiocarcinoma. Am J Roentgenol 169:1501–1505
44.
Zurück zum Zitat Hundt W, Petsch R, Scheidler J, Reiser M (2002) Clinical evaluation of further-developed MRCP sequences in comparison with standard MRCP sequences. Eur Radiol 12:1768–1777PubMed Hundt W, Petsch R, Scheidler J, Reiser M (2002) Clinical evaluation of further-developed MRCP sequences in comparison with standard MRCP sequences. Eur Radiol 12:1768–1777PubMed
45.
Zurück zum Zitat Prassopoulos P, Papanikolaou N, Maris T, Gogas C, Mouzas J, Gourtsoyiannis N (2002) Development of contrast-enhanced virtual MR cholangioscopy: a feasibility study. Eur Radiol 12:1438–1441PubMed Prassopoulos P, Papanikolaou N, Maris T, Gogas C, Mouzas J, Gourtsoyiannis N (2002) Development of contrast-enhanced virtual MR cholangioscopy: a feasibility study. Eur Radiol 12:1438–1441PubMed
46.
Zurück zum Zitat Ba-Ssalamah A, Heinz-Peer G, Schima W et al (2000) Detection of focal hepatic lesions: comparison of unenhanced and SHU 555 A-enhanced MR imaging versus biphasic helical CTAP. J Magn Reson Imaging 11:665–672PubMed Ba-Ssalamah A, Heinz-Peer G, Schima W et al (2000) Detection of focal hepatic lesions: comparison of unenhanced and SHU 555 A-enhanced MR imaging versus biphasic helical CTAP. J Magn Reson Imaging 11:665–672PubMed
47.
Zurück zum Zitat Lee SS, Kim MH, Lee SK et al (2002) MR cholangiography versus cholangioscopy for evaluation of longitudinal extension of hilar cholangiocarcinoma. Gastrointest Endosc 56:25–32PubMed Lee SS, Kim MH, Lee SK et al (2002) MR cholangiography versus cholangioscopy for evaluation of longitudinal extension of hilar cholangiocarcinoma. Gastrointest Endosc 56:25–32PubMed
48.
Zurück zum Zitat Lopera JE, Soto JA, Munera F (2001) Malignant hilar and perihilar biliary obstruction: use of MR cholangiography to define the extent of biliary ductal involvement and plan percutaneous interventions. Radiology 220:90–96PubMed Lopera JE, Soto JA, Munera F (2001) Malignant hilar and perihilar biliary obstruction: use of MR cholangiography to define the extent of biliary ductal involvement and plan percutaneous interventions. Radiology 220:90–96PubMed
49.
Zurück zum Zitat Pavone P, Laghi A, Catalano C, Panebianco V, Fabiano S, Passariello R (1999) MRI of the biliary and pancreatic ducts. Eur Radiol 9:1513–1522CrossRefPubMed Pavone P, Laghi A, Catalano C, Panebianco V, Fabiano S, Passariello R (1999) MRI of the biliary and pancreatic ducts. Eur Radiol 9:1513–1522CrossRefPubMed
50.
Zurück zum Zitat Holzknecht N, Gauger J, Sackmann M et al (1998) Breath-hold MR cholangiography with snapshot techniques: prospective comparison with endoscopic retrograde cholangiography. Radiology 206:657–664PubMed Holzknecht N, Gauger J, Sackmann M et al (1998) Breath-hold MR cholangiography with snapshot techniques: prospective comparison with endoscopic retrograde cholangiography. Radiology 206:657–664PubMed
51.
Zurück zum Zitat Wiedmann M, Caca K, Berr F et al (2003) Neoadjuvant photodynamic therapy as a new approach to treating hilar cholangiocarcinoma: a phase II pilot study. Cancer 97:2783–2790CrossRefPubMed Wiedmann M, Caca K, Berr F et al (2003) Neoadjuvant photodynamic therapy as a new approach to treating hilar cholangiocarcinoma: a phase II pilot study. Cancer 97:2783–2790CrossRefPubMed
52.
Zurück zum Zitat Lee MG, Park KB, Shin YM et al (2003) Preoperative evaluation of hilar cholangiocarcinoma with contrast-enhanced three-dimensional fast imaging with steady-state precession magnetic resonance angiography: comparison with intraarterial digital subtraction angiography. World J Surg 27:278–283CrossRefPubMed Lee MG, Park KB, Shin YM et al (2003) Preoperative evaluation of hilar cholangiocarcinoma with contrast-enhanced three-dimensional fast imaging with steady-state precession magnetic resonance angiography: comparison with intraarterial digital subtraction angiography. World J Surg 27:278–283CrossRefPubMed
53.
Zurück zum Zitat Smedby O, Riesenfeld V, Karlson B et al (1997) Magnetic resonance angiography in the resectability assessment of suspected pancreatic tumours. Eur Radiol 7:649–653PubMed Smedby O, Riesenfeld V, Karlson B et al (1997) Magnetic resonance angiography in the resectability assessment of suspected pancreatic tumours. Eur Radiol 7:649–653PubMed
54.
Zurück zum Zitat Catalano C, Pavone P, Laghi A et al (1998) Pancreatic adenocarcinoma: combination of MR imaging, MR angiography and MR cholangiopancreatography for the diagnosis and assessment of resectability. Eur Radiol 8:428–434PubMed Catalano C, Pavone P, Laghi A et al (1998) Pancreatic adenocarcinoma: combination of MR imaging, MR angiography and MR cholangiopancreatography for the diagnosis and assessment of resectability. Eur Radiol 8:428–434PubMed
55.
Zurück zum Zitat Fritscher-Ravens A, Bohuslavizki KH, Broering DC et al (2001) FDG PET in the diagnosis of hilar cholangiocarcinoma. Nucl Med Commun 22:1277–1285CrossRefPubMed Fritscher-Ravens A, Bohuslavizki KH, Broering DC et al (2001) FDG PET in the diagnosis of hilar cholangiocarcinoma. Nucl Med Commun 22:1277–1285CrossRefPubMed
56.
Zurück zum Zitat Keiding S, Hansen SB, Rasmussen HH et al (1998) Detection of cholangiocarcinoma in primary sclerosing cholangitis by positron emission tomography. Hepatology 28:700–706PubMed Keiding S, Hansen SB, Rasmussen HH et al (1998) Detection of cholangiocarcinoma in primary sclerosing cholangitis by positron emission tomography. Hepatology 28:700–706PubMed
57.
Zurück zum Zitat Kim YJ, Yun M, Lee WJ, Kim KS, Lee JD (2003) Usefulness of (18)F-FDG PET in intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging 30:1467–1472CrossRefPubMed Kim YJ, Yun M, Lee WJ, Kim KS, Lee JD (2003) Usefulness of (18)F-FDG PET in intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging 30:1467–1472CrossRefPubMed
Metadaten
Titel
Cross-sectional imaging of biliary tumors: current clinical status and future developments
verfasst von
Christoph J. Zech
Stefan O. Schoenberg
Maximilian Reiser
Thomas Helmberger
Publikationsdatum
01.07.2004
Erschienen in
European Radiology / Ausgabe 7/2004
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-004-2327-z

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