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Skeletal Radiology

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30.03.2020 | Scientific Article

CT-guided bone marrow aspirations and biopsies: retrospective study and comparison with blind procedures

verfasst von: C. Y. Chang, J. S. Husseini, A. Moreira, F. J. Simeone, A. J. Yee, M. A. Bredella, R. Hasserjian

Erschienen in: Skeletal Radiology | Ausgabe 8/2020

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Abstract

Purpose

To compare the pathology results of CT-guided and blind bone marrow aspirations and biopsies.

Methods

Ninety-eight consecutive CT-guided biopsies and 98 age- and gender-matched blind (non-CT-guided) posterior iliac crest bone marrow aspirations and biopsies performed in 2017 were reviewed for adequacy of core biopsies and aspirate smears. CT procedure images and CT abdomen/pelvis images were reviewed to evaluate anatomic features of the posterior ilium and soft tissues. Statistical analysis was performed using a T test, Fisher exact test, and Kruskal-Wallis test.

Results

There was no significant difference in the age and gender of the two groups (p > 0.05). However, the CT-guided group had a higher BMI (p = 0.0049) and posterior soft tissue thickness (p = 0.0016). More CT-guided biopsy samples (CT 93 (95%); blind 77 (79%); p = 0.0006) and aspirate smears (CT 90 (92%); blind 78 (80%); p = 0.042) were categorized as adequate. The CT-guided group had longer core lengths (CT 1.4 ± 0.6 (range 0.3–3.5) cm; blind 1.0 ± 0.60 (range 0–2.6) cm; p = 0.0001). Overall, 131/164 (80%) of the cases had at least one of the described features (slanted posterior ilium (angle > 30°), 30%; rounded posterior ilium, 20%; thick posterior ilium cortex, 13%; focal lesion in posterior ilium, 12%; prior procedure in posterior ilium, 5%; posterior soft tissue thickness > 3 cm, 40%).

Conclusion

CT-guided bone marrow procedures were more likely to result in both adequate aspirate smears and biopsy samples and longer core lengths when compared with blind procedures.

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Titel: CT-guided bone marrow aspirations and biopsies: retrospective study and comparison with blind procedures
verfasst von: C. Y. Chang
J. S. Husseini
A. Moreira
F. J. Simeone
A. J. Yee
M. A. Bredella
R. Hasserjian
Publikationsdatum: 30.03.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Skeletal Radiology / Ausgabe 8/2020
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-020-03423-x

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CT-guided bone marrow aspirations and biopsies: retrospective study and comparison with blind procedures