Skip to main content
Erschienen in: Neuroradiology 6/2017

27.03.2017 | Paediatric Neuroradiology

CT reconstruction and MRI fusion of 3D rotational angiography in the evaluation of pediatric cerebrovascular lesions

verfasst von: Prakash Muthusami, Nicholas Shkumat, Vanessa Rea, Albert H. Chiu, Manohar Shroff

Erschienen in: Neuroradiology | Ausgabe 6/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Complex neurovascular lesions in children require precise anatomic understanding for treatment planning. Although 3DRA is commonly employed for volumetric reformation in neurointerventional procedures, the ability to reconstruct this data into CT-like images (3DRA-CT) is not widely utilized. This study demonstrates the feasibility and usefulness of 3DRA-CT and subsequent MRI fusion for problem solving in pediatric neuroangiography.

Methods

This retrospective study includes 18 3DRA-CT studies in 16 children (age 9.6 ± 3.8 years, range 2–16 years) over 1 year. After biplane 2D-digital subtraction angiography (DSA), 5-second 3DRA was performed with selective vessel injection either with or without subtraction. Images were reconstructed into CT sections which were post-processed to generate multiplanar reformation (MPR) and maximum intensity projection (MIP) images. Fusion was performed with 3D T1 MRI images to precisely demonstrate neurovascular relationships. Quantitative radiation metrics were extracted and compared against those for the entire examination and for corresponding biplane 2D-DSA acquisitions.

Results

In all 18 cases, the 3DRA procedure and MRI fusion were technically successful and provided clinically useful information relevant to management. The unsubtracted and subtracted 3DRA acquisitions were measured to deliver 5.9 and 132.2%, respectively, of the mean radiation dose of corresponding biplane 2D-DSA acquisitions and contributed 1.2 and 12.5%, respectively, to the total procedure dose.

Conclusion

Lower radiation doses, high spatial resolution, and multiplanar reformatting capability make 3DRA-CT a useful adjunct to evaluate neurovascular lesions in children. Fusing 3DRA-CT data with MRI is an additional capability that can further enhance diagnostic information.
Literatur
1.
Zurück zum Zitat Honarmand AR, Gemmete JJ, Hurley MC, Shaibani A, Chaudhary N, Pandey AS et al (2015) Adjunctive value of intra-arterial cone beam CT angiography relative to DSA in the evaluation of cranial and spinal arteriovenous fistulas. J Neuro Interventional Surg 7(7):517–523 Honarmand AR, Gemmete JJ, Hurley MC, Shaibani A, Chaudhary N, Pandey AS et al (2015) Adjunctive value of intra-arterial cone beam CT angiography relative to DSA in the evaluation of cranial and spinal arteriovenous fistulas. J Neuro Interventional Surg 7(7):517–523
2.
Zurück zum Zitat Safain MG, Rahal JP, Patel S, Lauric A, Feldmann E, Malek AM (2014) Superior performance of cone-beam CT angiography in characterization of intracranial atherosclerosis. J Neurosurg 121(2):441–449CrossRefPubMed Safain MG, Rahal JP, Patel S, Lauric A, Feldmann E, Malek AM (2014) Superior performance of cone-beam CT angiography in characterization of intracranial atherosclerosis. J Neurosurg 121(2):441–449CrossRefPubMed
3.
Zurück zum Zitat Eesa M, Sharma P, Mitha AP, Sutherland GR, Goyal M (2009) Angiographic computed tomography with selective microcatheterization in delineating surgical anatomy in the case of a dural arteriovenous fistula. Technical note J Neurosurg 111(5):916–918CrossRefPubMed Eesa M, Sharma P, Mitha AP, Sutherland GR, Goyal M (2009) Angiographic computed tomography with selective microcatheterization in delineating surgical anatomy in the case of a dural arteriovenous fistula. Technical note J Neurosurg 111(5):916–918CrossRefPubMed
4.
Zurück zum Zitat Schulz CJ, Schmitt M, Böckler D, Geisbüsch P (2016) Intraoperative contrast-enhanced cone beam computed tomography to assess technical success during endovascular aneurysm repair. J Vasc Surg 64(3):577–584CrossRefPubMed Schulz CJ, Schmitt M, Böckler D, Geisbüsch P (2016) Intraoperative contrast-enhanced cone beam computed tomography to assess technical success during endovascular aneurysm repair. J Vasc Surg 64(3):577–584CrossRefPubMed
5.
Zurück zum Zitat Patel NV, Gounis MJ, Wakhloo AK, Noordhoek N, Blijd J, Babic D et al (2011) Contrast-enhanced angiographic cone-beam CT of cerebrovascular stents: experimental optimization and clinical application. AJNR Am J Neuroradiol 32(1):137–144PubMed Patel NV, Gounis MJ, Wakhloo AK, Noordhoek N, Blijd J, Babic D et al (2011) Contrast-enhanced angiographic cone-beam CT of cerebrovascular stents: experimental optimization and clinical application. AJNR Am J Neuroradiol 32(1):137–144PubMed
6.
Zurück zum Zitat Clarençon F, Piotin M, Pistocchi S, Babic D, Blanc R (2012) Evaluation of stent visibility by flat panel detector CT in patients treated for intracranial aneurysms. Neuroradiology 54(10):1121–1125CrossRefPubMed Clarençon F, Piotin M, Pistocchi S, Babic D, Blanc R (2012) Evaluation of stent visibility by flat panel detector CT in patients treated for intracranial aneurysms. Neuroradiology 54(10):1121–1125CrossRefPubMed
7.
Zurück zum Zitat Heran NS, Song JK, Namba K, Smith W, Niimi Y, Berenstein A (2006) The utility of Dyna CT in neuroendovascular procedures. Am J Neuroradiol 27(2):330–332PubMed Heran NS, Song JK, Namba K, Smith W, Niimi Y, Berenstein A (2006) The utility of Dyna CT in neuroendovascular procedures. Am J Neuroradiol 27(2):330–332PubMed
8.
Zurück zum Zitat Shinohara Y, Sakamoto M, Takeuchi H, Uno T, Watanabe T, Kaminou T et al (2013) Subarachnoid hyperattenuation on flat panel detector-based conebeam CT immediately after uneventful coil embolization of unruptured intracranial aneurysms. AJNR Am J Neuroradiol 34(3):577–582CrossRefPubMed Shinohara Y, Sakamoto M, Takeuchi H, Uno T, Watanabe T, Kaminou T et al (2013) Subarachnoid hyperattenuation on flat panel detector-based conebeam CT immediately after uneventful coil embolization of unruptured intracranial aneurysms. AJNR Am J Neuroradiol 34(3):577–582CrossRefPubMed
9.
Zurück zum Zitat Orth RC, Wallace MJ, Kuo MD (2009) C-arm cone-beam CT: general principles and technical considerations for use in interventional radiology. J Vasc Interv Radiol 20(7):S538–S544CrossRef Orth RC, Wallace MJ, Kuo MD (2009) C-arm cone-beam CT: general principles and technical considerations for use in interventional radiology. J Vasc Interv Radiol 20(7):S538–S544CrossRef
10.
Zurück zum Zitat Bai M, Liu B, Mu H, Liu X, Jiang Y (2012) The comparison of radiation dose between C-arm flat-detector CT (Dyna CT) and multi-slice CT (MSCT): a phantom study. Eur J Radiol 81(11):3577–3580CrossRefPubMed Bai M, Liu B, Mu H, Liu X, Jiang Y (2012) The comparison of radiation dose between C-arm flat-detector CT (Dyna CT) and multi-slice CT (MSCT): a phantom study. Eur J Radiol 81(11):3577–3580CrossRefPubMed
11.
Zurück zum Zitat van Rooij WJ, Sprengers ME, de Gast AN, Peluso JPP, Sluzewski M (2008) 3D rotational angiography: the new gold standard in the detection of additional intracranial aneurysms. Am J Neuroradiol 29(5):976–979CrossRefPubMed van Rooij WJ, Sprengers ME, de Gast AN, Peluso JPP, Sluzewski M (2008) 3D rotational angiography: the new gold standard in the detection of additional intracranial aneurysms. Am J Neuroradiol 29(5):976–979CrossRefPubMed
12.
Zurück zum Zitat Bechan RS, van Rooij SB, Sprengers ME, Peluso JP, Sluzewski M, Majoie CB et al (2015) CT angiography versus 3D rotational angiography in patients with subarachnoid hemorrhage. Neuroradiology 57(12):1239–1246CrossRefPubMed Bechan RS, van Rooij SB, Sprengers ME, Peluso JP, Sluzewski M, Majoie CB et al (2015) CT angiography versus 3D rotational angiography in patients with subarachnoid hemorrhage. Neuroradiology 57(12):1239–1246CrossRefPubMed
13.
Zurück zum Zitat Shi W-Y, Li Y-D, Li M-H, Gu B-X, Chen S-W, Wang W et al (2010) 3D rotational angiography with volume rendering: the utility in the detection of intracranial aneurysms. Neurol India 58(6):908–913CrossRefPubMed Shi W-Y, Li Y-D, Li M-H, Gu B-X, Chen S-W, Wang W et al (2010) 3D rotational angiography with volume rendering: the utility in the detection of intracranial aneurysms. Neurol India 58(6):908–913CrossRefPubMed
14.
Zurück zum Zitat Ruijters D, Homan R, Mielekamp P, van de Haar P, Babic D (2011) Validation of 3D multimodality roadmapping in interventional neuroradiology. Phys Med Biol 56(16):5335–5354CrossRefPubMed Ruijters D, Homan R, Mielekamp P, van de Haar P, Babic D (2011) Validation of 3D multimodality roadmapping in interventional neuroradiology. Phys Med Biol 56(16):5335–5354CrossRefPubMed
15.
Zurück zum Zitat Hiu T, Kitagawa N, Morikawa M, Hayashi K, Horie N, Morofuji Y et al (2009) Efficacy of Dyna CT digital angiography in the detection of the fistulous point of dural arteriovenous fistulas. Am J Neuroradiol 30(3):487–491CrossRefPubMed Hiu T, Kitagawa N, Morikawa M, Hayashi K, Horie N, Morofuji Y et al (2009) Efficacy of Dyna CT digital angiography in the detection of the fistulous point of dural arteriovenous fistulas. Am J Neuroradiol 30(3):487–491CrossRefPubMed
16.
Zurück zum Zitat Kakeda S, Korogi Y, Miyaguni Y, Moriya J, Ohnari N, Oda N et al (2007) A cone-beam volume CT using a 3D angiography system with a flat panel detector of direct conversion type: usefulness for superselective intra-arterial chemotherapy for head and neck tumors. Am J Neuroradiol 28(9):1783–1788CrossRefPubMed Kakeda S, Korogi Y, Miyaguni Y, Moriya J, Ohnari N, Oda N et al (2007) A cone-beam volume CT using a 3D angiography system with a flat panel detector of direct conversion type: usefulness for superselective intra-arterial chemotherapy for head and neck tumors. Am J Neuroradiol 28(9):1783–1788CrossRefPubMed
18.
Zurück zum Zitat Aadland TD, Thielen KR, Kaufmann TJ, Morris JM, Lanzino G, Kallmes DF et al (2010) 3D C—arm conebeam CT angiography as an adjunct in the precise anatomic characterization of spinal dural arteriovenous fistulas. Am J Neuroradiol 31(3):476–480CrossRefPubMed Aadland TD, Thielen KR, Kaufmann TJ, Morris JM, Lanzino G, Kallmes DF et al (2010) 3D C—arm conebeam CT angiography as an adjunct in the precise anatomic characterization of spinal dural arteriovenous fistulas. Am J Neuroradiol 31(3):476–480CrossRefPubMed
19.
Zurück zum Zitat Wang C, Nguyen G, Toncheva G, Jiang X, Ferrell A, Smith T et al (2014) Evaluation of patient effective dose of neurovascular imaging protocols for C-arm cone-beam CT. AJR Am J Roentgenol 202(5):1072–1077CrossRefPubMed Wang C, Nguyen G, Toncheva G, Jiang X, Ferrell A, Smith T et al (2014) Evaluation of patient effective dose of neurovascular imaging protocols for C-arm cone-beam CT. AJR Am J Roentgenol 202(5):1072–1077CrossRefPubMed
20.
Zurück zum Zitat Seguchi S, Saijou T, Ishikawa Y, Koyama S (2014) Radiation dose evaluation in 3D rotation angiography and cone-beam computed tomography with a flat panel detector. Nihon Hōshasen Gijutsu Gakkai Zasshi 70(7):646–652CrossRefPubMed Seguchi S, Saijou T, Ishikawa Y, Koyama S (2014) Radiation dose evaluation in 3D rotation angiography and cone-beam computed tomography with a flat panel detector. Nihon Hōshasen Gijutsu Gakkai Zasshi 70(7):646–652CrossRefPubMed
21.
Zurück zum Zitat Guberina N, Lechel U, Forsting M, Mönninghoff C, Dietrich U, Ringelstein A (2016) Dose comparison of classical 2-plane DSA and 3D rotational angiography for the assessment of intracranial aneurysms. Neuroradiology 12 Guberina N, Lechel U, Forsting M, Mönninghoff C, Dietrich U, Ringelstein A (2016) Dose comparison of classical 2-plane DSA and 3D rotational angiography for the assessment of intracranial aneurysms. Neuroradiology 12
22.
Zurück zum Zitat Abe T, Hirohata M, Tanaka N, Uchiyama Y, Kojima K, Fujimoto K et al (2002) Clinical benefits of rotational 3D angiography in endovascular treatment of ruptured cerebral aneurysm. AJNR Am J Neuroradiol 23(4):686–688PubMed Abe T, Hirohata M, Tanaka N, Uchiyama Y, Kojima K, Fujimoto K et al (2002) Clinical benefits of rotational 3D angiography in endovascular treatment of ruptured cerebral aneurysm. AJNR Am J Neuroradiol 23(4):686–688PubMed
Metadaten
Titel
CT reconstruction and MRI fusion of 3D rotational angiography in the evaluation of pediatric cerebrovascular lesions
verfasst von
Prakash Muthusami
Nicholas Shkumat
Vanessa Rea
Albert H. Chiu
Manohar Shroff
Publikationsdatum
27.03.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Neuroradiology / Ausgabe 6/2017
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-017-1818-y

Weitere Artikel der Ausgabe 6/2017

Neuroradiology 6/2017 Zur Ausgabe

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Frühe Alzheimertherapie lohnt sich

25.04.2024 AAN-Jahrestagung 2024 Nachrichten

Ist die Tau-Last noch gering, scheint der Vorteil von Lecanemab besonders groß zu sein. Und beginnen Erkrankte verzögert mit der Behandlung, erreichen sie nicht mehr die kognitive Leistung wie bei einem früheren Start. Darauf deuten neue Analysen der Phase-3-Studie Clarity AD.

Viel Bewegung in der Parkinsonforschung

25.04.2024 Parkinson-Krankheit Nachrichten

Neue arznei- und zellbasierte Ansätze, Frühdiagnose mit Bewegungssensoren, Rückenmarkstimulation gegen Gehblockaden – in der Parkinsonforschung tut sich einiges. Auf dem Deutschen Parkinsonkongress ging es auch viel um technische Innovationen.

Demenzkranke durch Antipsychotika vielfach gefährdet

23.04.2024 Demenz Nachrichten

Wenn Demenzkranke aufgrund von Symptomen wie Agitation oder Aggressivität mit Antipsychotika behandelt werden, sind damit offenbar noch mehr Risiken verbunden als bislang angenommen.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.