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Erschienen in: Current Heart Failure Reports 6/2018

06.11.2018 | Comorbidities of Heart Failure (C Angermann, Section Editor)

Depression, Anxiety, and Cognitive Impairment

Comorbid Mental Health Disorders in Heart Failure

verfasst von: Christiane E. Angermann, Georg Ertl

Erschienen in: Current Heart Failure Reports | Ausgabe 6/2018

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Abstract

Purpose of Review

Depression, anxiety, and cognitive impairment constitute established risk markers for incident cardiovascular disease (CVD) and are associated with impaired life expectancy and quality of life and high hospitalization rates and healthcare expenditure. This review summarizes current knowledge about mental health disorders in patients with CVD and heart failure (HF).

Recent Findings

Emerging evidence suggests various shared pathophysiological mechanisms between psychological comorbidities and CVD (e.g., systemic inflammation and autonomic dysfunction). Bi-directional interactions involving the central nervous and cardiovascular systems may help explain the rising prevalence of comorbid mood disorders with increasing CVD severity and support the concept of alternative pathophysiological mechanisms in the presence of severe somatic illness, making symptoms less responsive or unresponsive to psychotropic pharmacotherapy.

Summary

Considering high prevalence and negative impact of psychological comorbidities in CVD and HF, routine care should integrate screening for these conditions. Multidisciplinary treatment approaches with active patient participation in disease management were shown to improve outcomes. However, better understanding of factors mediating the adverse prognostic effects of mood disorders is needed. This might enable more targeted treatment and possibly also facilitate better understanding of the pathophysiological mechanisms driving CVD.
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Metadaten
Titel
Depression, Anxiety, and Cognitive Impairment
Comorbid Mental Health Disorders in Heart Failure
verfasst von
Christiane E. Angermann
Georg Ertl
Publikationsdatum
06.11.2018
Verlag
Springer US
Erschienen in
Current Heart Failure Reports / Ausgabe 6/2018
Print ISSN: 1546-9530
Elektronische ISSN: 1546-9549
DOI
https://doi.org/10.1007/s11897-018-0414-8

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