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Journal of Nuclear Cardiology

Erschienen in:

13.01.2021 | EDITORIAL

Deriving myocardial blood flow reserve from perfusion datasets: Dream or reality?

verfasst von: Alexis Poitrasson-Rivière, PhD, Venkatesh L. Murthy, MD, PhD

Erschienen in: Journal of Nuclear Cardiology | Ausgabe 3/2021

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Excerpt

Although quantitative estimates of myocardial blood flow (MBF) and flow reserve (MFR) from positron emission tomography (PET) myocardial perfusion imaging (MPI) have widely recognized value,1-3 accurate estimates require high-quality scanners, as well as rigorous injection and optimized acquisition protocols.4 Dynamic series used for computation of MBF and MFR are prone to numerous quality issues including patient motion and scanner saturation. Although the former can be readily recognized and corrected,5-7 identification of saturation by inspection of dynamic series is not straightforward or reliable.8 Furthermore, obtaining data without saturation is near impossible with certain older scanners. Consequently, there is great interest in simpler alternatives to standard kinetic modeling approaches,9,10 which are robust to these issues. Toward this end, work by Juneau et al in the present issue of the Journal of Nuclear Cardiology investigates the estimation of MFR from the myocardial activity ratio (MAR) from static images.11 …

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Poitrasson-Rivière A, Moody JB, Hagio T, Weinberg RL, Corbett JR, Murthy VL, et al. Reducing motion-correction-induced variability in ⁸²rubidium myocardial blood-flow quantification. J Nucl Cardiol 2020;27:1104-13. https://doi.org/10.1007/s12350-019-01911-9.CrossRefPubMed

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Juneau D, Wu KY, Kaps N, Yao J, Renaud JM, Beanlands RSB, et al. Internal validation of myocardial flow reserve PET imaging using stress/rest myocardial activity ratios with Rb-82 and N-13-ammonia. J Nucl Cardiol 2021. https://doi.org/10.1007/s12350-020-02464-y.CrossRefPubMed

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Titel: Deriving myocardial blood flow reserve from perfusion datasets: Dream or reality?
verfasst von: Alexis Poitrasson-Rivière, PhD
Venkatesh L. Murthy, MD, PhD
Publikationsdatum: 13.01.2021
Verlag: Springer International Publishing
Erschienen in: Journal of Nuclear Cardiology / Ausgabe 3/2021
Print ISSN: 1071-3581
Elektronische ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-020-02488-4

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