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Erschienen in: Journal of Digital Imaging 3/2010

01.06.2010

Detection of the Optic Nerve Head in Fundus Images of the Retina Using the Hough Transform for Circles

verfasst von: Xiaolu Zhu, Rangaraj M. Rangayyan, Anna L. Ells

Erschienen in: Journal of Imaging Informatics in Medicine | Ausgabe 3/2010

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Abstract

Detection of the optic nerve head (ONH) is a key preprocessing component in algorithms for the automatic extraction of the anatomical structures of the retina. We propose a method to automatically locate the ONH in fundus images of the retina. The method includes edge detection using the Sobel operators and detection of circles using the Hough transform. The Hough transform assists in the detection of the center and radius of a circle that approximates the margin of the ONH. Forty images of the retina from the Digital Retinal Images for Vessel Extraction (DRIVE) dataset were used to test the performance of the proposed method. The center and boundary of the ONH were independently marked by an ophthalmologist for evaluation. Free-response receiver operating characteristics (FROC) analysis as well as measures of distance and overlap were used to evaluate the performance of the proposed method. The centers of the ONH were detected with an average distance of 0.36 mm to the corresponding centers marked by the ophthalmologist; the detected circles had an average overlap of 0.73 with the boundaries of the ONH drawn by the ophthalmologist. FROC analysis indicated a sensitivity of detection of 92.5% at 8.9 false-positives per image. With an intensity-based criterion for the selection of the circle and a limit of 40 pixels (0.8 mm) on the distance between the center of the detected circle and the manually identified center of the ONH, a successful detection rate of 90% was obtained with the DRIVE dataset.
Literatur
1.
Zurück zum Zitat Fleming AD, Goatman KA, Philip S, Olson JA, Sharp PF: Automatic detection of retinal anatomy to assist diabetic retinopathy screening. Phys Med Biol 52:331–345, 2007CrossRefPubMed Fleming AD, Goatman KA, Philip S, Olson JA, Sharp PF: Automatic detection of retinal anatomy to assist diabetic retinopathy screening. Phys Med Biol 52:331–345, 2007CrossRefPubMed
2.
Zurück zum Zitat Park M, Jin JS, Luo S: Locating the optic disc in retinal images. In Proceedings of the International Conference on Computer Graphics, Imaging and Visualisation, IEEE, Sydney, QLD, Australia, July, 2006, p 5 Park M, Jin JS, Luo S: Locating the optic disc in retinal images. In Proceedings of the International Conference on Computer Graphics, Imaging and Visualisation, IEEE, Sydney, QLD, Australia, July, 2006, p 5
3.
Zurück zum Zitat Michaelson IC, Benezra D: Textbook of the Fundus of the Eye, 3rd edition. Edinburgh, UK: Churchill Livingstone, 1980 Michaelson IC, Benezra D: Textbook of the Fundus of the Eye, 3rd edition. Edinburgh, UK: Churchill Livingstone, 1980
4.
Zurück zum Zitat Ells A, Holmes JM, Astle WF, Williams G, Leske DA, Fielden M, Uphill B, Jennett P, Hebert M: Telemedicine approach to screening for severe retinopathy of prematurity: a pilot study. Ophthalmology 110(11):2113–2117, 2003CrossRefPubMed Ells A, Holmes JM, Astle WF, Williams G, Leske DA, Fielden M, Uphill B, Jennett P, Hebert M: Telemedicine approach to screening for severe retinopathy of prematurity: a pilot study. Ophthalmology 110(11):2113–2117, 2003CrossRefPubMed
5.
Zurück zum Zitat Patton N, Aslam TM, MacGillivray T, Deary IJ, Dhillon B, Eikelboom RH, Yogesan K, Constable IJ: Retinal image analysis: concepts, applications and potential. Progr Retin Eye Res 25(1):99–127, 2006CrossRef Patton N, Aslam TM, MacGillivray T, Deary IJ, Dhillon B, Eikelboom RH, Yogesan K, Constable IJ: Retinal image analysis: concepts, applications and potential. Progr Retin Eye Res 25(1):99–127, 2006CrossRef
6.
Zurück zum Zitat Acharya R, Tan W, Yun WL, Ng EYK, Min LC, Chee C, Gupta M, Nayak J, Suri JS: The human eye. In: Acharya R, Ng EYK, Suri JS Eds. Image Modeling of the Human Eye. Norwood, MA: Artech House, 2008, pp. 1–35 Acharya R, Tan W, Yun WL, Ng EYK, Min LC, Chee C, Gupta M, Nayak J, Suri JS: The human eye. In: Acharya R, Ng EYK, Suri JS Eds. Image Modeling of the Human Eye. Norwood, MA: Artech House, 2008, pp. 1–35
7.
Zurück zum Zitat Staal J, Abràmoff MD, Niemeijer M, Viergever MA, van Ginneken B: Ridge-based vessel segmentation in color images of the retina. IEEE Trans Med Imag 23(4):501–509, 2004CrossRef Staal J, Abràmoff MD, Niemeijer M, Viergever MA, van Ginneken B: Ridge-based vessel segmentation in color images of the retina. IEEE Trans Med Imag 23(4):501–509, 2004CrossRef
9.
Zurück zum Zitat Barrett SF, Naess E, Molvik T: Employing the Hough transform to locate the optic disk. Biomed Sci Instrum 37:81–86, 2001PubMed Barrett SF, Naess E, Molvik T: Employing the Hough transform to locate the optic disk. Biomed Sci Instrum 37:81–86, 2001PubMed
10.
Zurück zum Zitat ter Haar F: Automatic localization of the optic disc in digital colour images of the human retina. Master’s thesis, Utrecht University, Utrecht, The Netherlands, 2005 ter Haar F: Automatic localization of the optic disc in digital colour images of the human retina. Master’s thesis, Utrecht University, Utrecht, The Netherlands, 2005
11.
Zurück zum Zitat Chrástek R, Skokan M, Kubecka L, Wolf M, Donath K, Jan J, Michelson G, Niemann H: Multimodal retinal image registration for optic disk segmentation. In Methods of Information in Medicine, German BVM-Workshop on Medical Image Processing, Schattauer GmbH, Germany, volume 43, 2004, pp 336–342 Chrástek R, Skokan M, Kubecka L, Wolf M, Donath K, Jan J, Michelson G, Niemann H: Multimodal retinal image registration for optic disk segmentation. In Methods of Information in Medicine, German BVM-Workshop on Medical Image Processing, Schattauer GmbH, Germany, volume 43, 2004, pp 336–342
12.
Zurück zum Zitat Chrástek R, Wolf M, Donath K, Niemann H, Paulus D, Hothorn T, Lausen B, Lämmer R, Mardin CY, Michelson G: Automated segmentation of the optic nerve head for diagnosis of glaucoma. Med Image Anal 9(4):297–314, 2005CrossRefPubMed Chrástek R, Wolf M, Donath K, Niemann H, Paulus D, Hothorn T, Lausen B, Lämmer R, Mardin CY, Michelson G: Automated segmentation of the optic nerve head for diagnosis of glaucoma. Med Image Anal 9(4):297–314, 2005CrossRefPubMed
13.
Zurück zum Zitat Sinthanayothin C, Boyce JF, Cook HL, Williamson TH: Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images. Br J Ophthalmol 83(4):902–910, 1999CrossRefPubMed Sinthanayothin C, Boyce JF, Cook HL, Williamson TH: Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images. Br J Ophthalmol 83(4):902–910, 1999CrossRefPubMed
14.
Zurück zum Zitat Osareh A, Mirmehd M, Thomas B, Markham R. Comparison of colour spaces for optic disc localisation in retinal images. In Proceedings 16th International Conference on Pattern Recognition, Quebec City, Quebec, Canada, 2002, pp 743–746 Osareh A, Mirmehd M, Thomas B, Markham R. Comparison of colour spaces for optic disc localisation in retinal images. In Proceedings 16th International Conference on Pattern Recognition, Quebec City, Quebec, Canada, 2002, pp 743–746
15.
Zurück zum Zitat Youssif AAHAR, Ghalwash AZ, Ghoneim AASAR: Optic disc detection from normalized digital fundus images by means of a vessels’ direction matched filter. IEEE Trans Med Imag 27(1):11–18, 2008CrossRef Youssif AAHAR, Ghalwash AZ, Ghoneim AASAR: Optic disc detection from normalized digital fundus images by means of a vessels’ direction matched filter. IEEE Trans Med Imag 27(1):11–18, 2008CrossRef
16.
Zurück zum Zitat Hoover A, Goldbaum M: Locating the optic nerve in a retinal image using the fuzzy convergence of the blood vessels. IEEE Trans Med Imag 22(8):951–958, 2003CrossRef Hoover A, Goldbaum M: Locating the optic nerve in a retinal image using the fuzzy convergence of the blood vessels. IEEE Trans Med Imag 22(8):951–958, 2003CrossRef
18.
Zurück zum Zitat Lalonde M, Beaulieu M, Gagnon L: Fast and robust optic disc detection using pyramidal decomposition and Hausdorff-based template matching. IEEE Trans Med Imag 20(11):1193–1200, 2001CrossRef Lalonde M, Beaulieu M, Gagnon L: Fast and robust optic disc detection using pyramidal decomposition and Hausdorff-based template matching. IEEE Trans Med Imag 20(11):1193–1200, 2001CrossRef
19.
Zurück zum Zitat Foracchia M, Grisan E, Ruggeri A: Detection of optic disc in retinal images by means of a geometrical model of vessel structure. IEEE Trans Med Imag 23(10):1189–1195, 2004CrossRef Foracchia M, Grisan E, Ruggeri A: Detection of optic disc in retinal images by means of a geometrical model of vessel structure. IEEE Trans Med Imag 23(10):1189–1195, 2004CrossRef
20.
Zurück zum Zitat Ying H, Zhang M, Liu JC: Fractal-based automatic localization and segmentation of optic disc in retinal images. In Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE, Lyon, France, August 23–26, 2007, pp 4139–4141 Ying H, Zhang M, Liu JC: Fractal-based automatic localization and segmentation of optic disc in retinal images. In Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE, Lyon, France, August 23–26, 2007, pp 4139–4141
21.
Zurück zum Zitat Kim SK, Kong HJ, Seo JM, Cho BJ, Park KH, Hwang JM, Kim DM, Chung H, Kim HC: Segmentation of optic nerve head using warping and RANSAC. In Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE, Lyon, France, August 23–26, 2007, pp 900–903 Kim SK, Kong HJ, Seo JM, Cho BJ, Park KH, Hwang JM, Kim DM, Chung H, Kim HC: Segmentation of optic nerve head using warping and RANSAC. In Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE, Lyon, France, August 23–26, 2007, pp 900–903
22.
Zurück zum Zitat Park J, Kien NT, Lee G: Optic disc detection in retinal images using tensor voting and adaptive mean-shift. In IEEE 3rd International Conference on Intelligent Computer Communication and Processing, ICCP, Cluj-Napoca, Romania, 2007, pp 237–241 Park J, Kien NT, Lee G: Optic disc detection in retinal images using tensor voting and adaptive mean-shift. In IEEE 3rd International Conference on Intelligent Computer Communication and Processing, ICCP, Cluj-Napoca, Romania, 2007, pp 237–241
23.
Zurück zum Zitat Carmona EJ, Rincon M, García-Feijoó J, Martínez de-la Casa JM: Identification of the optic nerve head with genetic algorithms. Artif Intell Med 43(3):243–259, 2008CrossRefPubMed Carmona EJ, Rincon M, García-Feijoó J, Martínez de-la Casa JM: Identification of the optic nerve head with genetic algorithms. Artif Intell Med 43(3):243–259, 2008CrossRefPubMed
24.
Zurück zum Zitat Hussain AR: Optic nerve head segmentation using genetic active contours. In Proceeding International Conference on Computer and Communication Engineering, IEEE, Kuala Lumpur, Malaysia, May 13–15, 2008, pp 783–787 Hussain AR: Optic nerve head segmentation using genetic active contours. In Proceeding International Conference on Computer and Communication Engineering, IEEE, Kuala Lumpur, Malaysia, May 13–15, 2008, pp 783–787
25.
Zurück zum Zitat Zhu X, Rangayyan RM: Detection of the optic disc in images of the retina using the Hough transform. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE, Vancouver, BC, Canada, August 20–24, 2008, pp 3546–3549 Zhu X, Rangayyan RM: Detection of the optic disc in images of the retina using the Hough transform. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE, Vancouver, BC, Canada, August 20–24, 2008, pp 3546–3549
27.
Zurück zum Zitat Gonzalez RC, Woods RE: Digital Image Processing, 2nd edition. Upper Saddle River, NJ: Prentice Hall, 2002 Gonzalez RC, Woods RE: Digital Image Processing, 2nd edition. Upper Saddle River, NJ: Prentice Hall, 2002
28.
Zurück zum Zitat Soares JVB, Leandro JJG, Cesar Jr., RM, Jelinek HF, Cree MJ: Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification. IEEE Trans Med Imag 25(9):1214–1222, 2006CrossRef Soares JVB, Leandro JJG, Cesar Jr., RM, Jelinek HF, Cree MJ: Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification. IEEE Trans Med Imag 25(9):1214–1222, 2006CrossRef
29.
Zurück zum Zitat Rangayyan RM, Ayres FJ, Oloumi F, Oloumi F, Eshghzadeh-Zanjani P: Detection of blood vessels in the retina with multiscale Gabor filters. J Electron Imaging 17(2):023018, 2008CrossRef Rangayyan RM, Ayres FJ, Oloumi F, Oloumi F, Eshghzadeh-Zanjani P: Detection of blood vessels in the retina with multiscale Gabor filters. J Electron Imaging 17(2):023018, 2008CrossRef
30.
Zurück zum Zitat Rangayyan RM: Biomedical Image Analysis, Boca Raton, FL: CRC, 2005 Rangayyan RM: Biomedical Image Analysis, Boca Raton, FL: CRC, 2005
32.
Zurück zum Zitat Canny J: A computational approach to edge detection. IEEE Trans Pattern Anal Mach Intell PAMI-8(6):670–698, 1986CrossRef Canny J: A computational approach to edge detection. IEEE Trans Pattern Anal Mach Intell PAMI-8(6):670–698, 1986CrossRef
33.
Zurück zum Zitat Hough PVC: Method and means for recognizing complex patterns. US Patent 3,069,654, December 18, 1962 Hough PVC: Method and means for recognizing complex patterns. US Patent 3,069,654, December 18, 1962
34.
Zurück zum Zitat Duda RO, Hart PE: Use of the Hough transformation to detect lines and curves in pictures. Commun ACM 15(1):11–15, 1972CrossRef Duda RO, Hart PE: Use of the Hough transformation to detect lines and curves in pictures. Commun ACM 15(1):11–15, 1972CrossRef
35.
Zurück zum Zitat Egan JP, Greenberg GZ, Schulman AI: Operating characteristics, signal detectability, and the method of free response. J Acoust Soc Am 33(8):993–1007, 1961CrossRef Egan JP, Greenberg GZ, Schulman AI: Operating characteristics, signal detectability, and the method of free response. J Acoust Soc Am 33(8):993–1007, 1961CrossRef
36.
Zurück zum Zitat Ayres FJ, Rangayyan RM: Design and performance analysis of oriented feature detectors. J Electron Imaging 16(2):023007, 2007CrossRef Ayres FJ, Rangayyan RM: Design and performance analysis of oriented feature detectors. J Electron Imaging 16(2):023007, 2007CrossRef
37.
Zurück zum Zitat Rangayyan RM, Ayres FJ: Gabor filters and phase portraits for the detection of architectural distortion in mammograms. Med Biol Eng Comput 44(10):883–894, 2006CrossRefPubMed Rangayyan RM, Ayres FJ: Gabor filters and phase portraits for the detection of architectural distortion in mammograms. Med Biol Eng Comput 44(10):883–894, 2006CrossRefPubMed
38.
Zurück zum Zitat Rangayyan RM, Zhu X, Ayres FJ: Detection of the optic disc in images of the retina using Gabor filters and phase portrait analysis. In Proceedings of 4th European Congress for Medical and Biomedical Engineering, IEEE, Antwerp, Belgium, November 23–27, 2008, pp 468–471 Rangayyan RM, Zhu X, Ayres FJ: Detection of the optic disc in images of the retina using Gabor filters and phase portrait analysis. In Proceedings of 4th European Congress for Medical and Biomedical Engineering, IEEE, Antwerp, Belgium, November 23–27, 2008, pp 468–471
Metadaten
Titel
Detection of the Optic Nerve Head in Fundus Images of the Retina Using the Hough Transform for Circles
verfasst von
Xiaolu Zhu
Rangaraj M. Rangayyan
Anna L. Ells
Publikationsdatum
01.06.2010
Verlag
Springer-Verlag
Erschienen in
Journal of Imaging Informatics in Medicine / Ausgabe 3/2010
Print ISSN: 2948-2925
Elektronische ISSN: 2948-2933
DOI
https://doi.org/10.1007/s10278-009-9189-5

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