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Journal of Hematopathology

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05.03.2020 | Letter to the editor

Does the order of mutational acquisition in myeloproliferative neoplasms matter? Evidence from JAK2 exon 12 and DNMT3A co-mutant polycythemia vera

verfasst von: Rumyana Todorova, Jakob Passweg, Pontus Lundberg, Alexandar Tzankov

Erschienen in: Journal of Hematopathology | Ausgabe 2/2020

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Excerpt

Myeloproliferative neoplasms (MPN) have in common an abnormal clonal expansion of differentiated hematopoietic cells in the bone marrow (BM), usually accompanied by excessive production of progenies leading to numeric blood cell increase. Three classical MPN types are recognized—polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). …

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Titel: Does the order of mutational acquisition in myeloproliferative neoplasms matter? Evidence from JAK2 exon 12 and DNMT3A co-mutant polycythemia vera
verfasst von: Rumyana Todorova
Jakob Passweg
Pontus Lundberg
Alexandar Tzankov
Publikationsdatum: 05.03.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Journal of Hematopathology / Ausgabe 2/2020
Print ISSN: 1868-9256
Elektronische ISSN: 1865-5785
DOI: https://doi.org/10.1007/s12308-020-00392-x

Springer Medizin

Does the order of mutational acquisition in myeloproliferative neoplasms matter? Evidence from JAK2 exon 12 and DNMT3A co-mutant polycythemia vera

Excerpt

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Excerpt

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